ID A0A212F7R6_DANPL Unreviewed; 850 AA.
AC A0A212F7R6;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Trachealess {ECO:0000313|EMBL:OWR49771.1, ECO:0000313|RefSeq:XP_032522358.1};
GN Name=LOC116773901 {ECO:0000313|RefSeq:XP_032522358.1};
GN ORFNames=KGM_212029 {ECO:0000313|EMBL:OWR49771.1};
OS Danaus plexippus plexippus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Nymphalidae; Danainae; Danaini; Danaina; Danaus; Danaus.
OX NCBI_TaxID=278856 {ECO:0000313|EMBL:OWR49771.1, ECO:0000313|Proteomes:UP000007151};
RN [1] {ECO:0000313|EMBL:OWR49771.1, ECO:0000313|Proteomes:UP000007151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F-2 {ECO:0000313|EMBL:OWR49771.1};
RX PubMed=22118469; DOI=10.1016/j.cell.2011.09.052;
RA Zhan S., Merlin C., Boore J.L., Reppert S.M.;
RT "The monarch butterfly genome yields insights into long-distance
RT migration.";
RL Cell 147:1171-1185(2011).
RN [2] {ECO:0000313|EMBL:OWR49771.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=F-2 {ECO:0000313|EMBL:OWR49771.1};
RA Zhan S., Reppert S.M.;
RT "MonarchBase: the monarch butterfly genome database.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:XP_032522358.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AGBW02009838; OWR49771.1; -; Genomic_DNA.
DR RefSeq; XP_032522358.1; XM_032666467.1.
DR STRING; 278856.A0A212F7R6; -.
DR EnsemblMetazoa; XM_032666467.1; XP_032522358.1; LOC116773901.
DR KEGG; dpl:KGM_212029; -.
DR eggNOG; KOG3558; Eukaryota.
DR OrthoDB; 5396877at2759; -.
DR Proteomes; UP000007151; Unassembled WGS sequence.
DR Proteomes; UP000596680; Chromosome 21.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR GO; GO:0048856; P:anatomical structure development; IEA:UniProt.
DR GO; GO:0045944; P:positive regulation of transcription by RNA polymerase II; IEA:UniProt.
DR CDD; cd19733; bHLH-PAS_trachealess_like; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR InterPro; IPR013655; PAS_fold_3.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR23043; HYPOXIA-INDUCIBLE FACTOR 1 ALPHA; 1.
DR PANTHER; PTHR23043:SF26; PROTEIN TRACHEALESS; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF08447; PAS_3; 1.
DR SMART; SM00353; HLH; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50888; BHLH; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000007151};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 76..129
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT DOMAIN 168..238
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 369..410
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT REGION 134..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 242..263
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 475..605
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 697..724
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 822..850
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 247..263
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 492..507
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 510..547
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 555..575
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 833..850
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 850 AA; 93174 MW; C17A36FC7C427B3D CRC64;
MLPYQTVAMD YAVASGFHHQ RPGLPGVMGL PGPGPGLNPG LNTAFTHSWF VQTSPDMCRQ
QQASNQSHLE PGILELRKEK SRDAARSRRG KENYEFYELA KMLPLPAAIT SQLDKASIIR
LTISYLKLRD FSGHGDPPWS RDTPPTSKTL KGTQNRRTPA GLAMELFEQH QGTHILQSLD
GFALSVAADG RFLYISETVS IYLGLSQVEM TGSSIFDYVH QADHAEIAEQ LGLSLAGRGG
AGLSSPASGS EEGSQHGTNN PDVSAQMTLA ASGALFRGMD RAFCVRMKST LTKRGCHFKS
SGYRVVLMLC RLRPQYTFSH SRKTPPTLLG MVALAIALPP PSVHEIRLES DMFVTRINFD
FRIAHCEPSR VSELLGYTAE ELTGKNLYAL CHGEDANKLR KCHVDLLNKG QVLTHYYRIM
NKLGGYTWMQ TCATVVCSSK NAEEQNIICV NYVISGREYP NTVMDCCQLE ESVQGVKREE
TTGDPENGPP DADSGGGPPP PRHPAERTEP PSNNDATSSA PPTSDVTHLT RLSDSQPLPL
HTTQERSSPM PRRLKKRKHT EDDDAERDEE RRKSSSNSTA ALSPVERDMT KANLSIPETS
DATSVRDLEN AMSKHLPSLD GKEISHRPTD FSTDALLKQQ QQKSTIQWIG AQNHHLNHLN
RQLPGNHTPT PASALLRQLY ANRESVIRSN FLGDGRTGGY YSSDGQSGPL PTPPGSEGSG
YGEQLGHKGT DIGSLAYAGY ADYHSAMTPP GSVSPRDKQQ YALPYDNSYS EALRHPYLGI
NSEAPLPLKP QAYSAVPGAL DYAQLDQSQF FHPSSSFHLY HPQAHAAHAS HSHQTDKSAP
PNTNWYSTSS
//
