ID A0A212F954_DANPL Unreviewed; 1433 AA.
AC A0A212F954;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=DE-cadherin like protein {ECO:0000313|EMBL:OWR50260.1};
DE Flags: Fragment;
GN ORFNames=KGM_216145B {ECO:0000313|EMBL:OWR50260.1};
OS Danaus plexippus plexippus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Nymphalidae; Danainae; Danaini; Danaina; Danaus; Danaus.
OX NCBI_TaxID=278856 {ECO:0000313|EMBL:OWR50260.1, ECO:0000313|Proteomes:UP000007151};
RN [1] {ECO:0000313|EMBL:OWR50260.1, ECO:0000313|Proteomes:UP000007151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F-2 {ECO:0000313|EMBL:OWR50260.1};
RX PubMed=22118469; DOI=10.1016/j.cell.2011.09.052;
RA Zhan S., Merlin C., Boore J.L., Reppert S.M.;
RT "The monarch butterfly genome yields insights into long-distance
RT migration.";
RL Cell 147:1171-1185(2011).
CC -!- FUNCTION: Cadherins are calcium-dependent cell adhesion proteins.
CC {ECO:0000256|RuleBase:RU004357}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU003318};
CC Single-pass type I membrane protein {ECO:0000256|RuleBase:RU003318}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00122}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWR50260.1}.
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DR EMBL; AGBW02009647; OWR50260.1; -; Genomic_DNA.
DR STRING; 278856.A0A212F954; -.
DR KEGG; dpl:KGM_216145B; -.
DR InParanoid; A0A212F954; -.
DR Proteomes; UP000007151; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0048513; P:animal organ development; IEA:UniProt.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR GO; GO:0001736; P:establishment of planar polarity; IEA:UniProt.
DR GO; GO:0007163; P:establishment or maintenance of cell polarity; IEA:UniProt.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 6.
DR CDD; cd00054; EGF_CA; 1.
DR CDD; cd00110; LamG; 1.
DR Gene3D; 2.60.120.200; -; 1.
DR Gene3D; 2.60.40.60; Cadherins; 7.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR Gene3D; 4.10.900.10; TCF3-CBD (Catenin binding domain); 1.
DR InterPro; IPR039808; Cadherin.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR000233; Cadherin_Y-type_LIR.
DR InterPro; IPR027397; Catenin-bd_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR001791; Laminin_G.
DR PANTHER; PTHR24027; CADHERIN-23; 1.
DR PANTHER; PTHR24027:SF422; NEURAL-CADHERIN 2-RELATED; 1.
DR Pfam; PF01049; CADH_Y-type_LIR; 1.
DR Pfam; PF00028; Cadherin; 6.
DR Pfam; PF02210; Laminin_G_2; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 7.
DR SMART; SM00282; LamG; 1.
DR SUPFAM; SSF49313; Cadherin-like; 8.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS00232; CADHERIN_1; 4.
DR PROSITE; PS50268; CADHERIN_2; 7.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50025; LAM_G_DOMAIN; 1.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell adhesion {ECO:0000256|RuleBase:RU003318};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007151};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU003318};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1263..1283
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 20..129
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 130..235
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 270..346
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 346..455
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 464..556
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 556..668
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 678..775
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 1059..1247
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:OWR50260.1"
SQ SEQUENCE 1433 AA; 160616 MW; E1FC97ACD49C846E CRC64;
FTPASPKLAV KDNHKPLFTE CLNYRPTLKE EQPVGTYVFT VHAEDRDPPE MGGTVTYKFV
STPGEKERFH VDPETGRITT ADIFDHDEPS REKEAYITVR ASDNGQPQLD DACTIKILIE
DINDNQPVFD KVSYSESVPQ DLPSGREVMR ISATDIDDGN NSIVHYSLDS NSPDQAYFYI
DPDNGVIFLN KTIDKVPGYK FKLSAIVKDM GDPPQQSSIT LDIQVVESNK KSPSFIEVPD
EPIRLKENYA DFNTPIATVR AVSNIPEEKK LQFELVMGQT EQTNKWHTFV LEPEADSAYI
KLGNHLDYEK ITDYTLTVRI QNNYKLAAET IIQIEIEDVN DNIPIFSEIR SGSVLENEPP
GTPVMQVRAF DADGTSANNQ VTYELGDPSD PFAIDSITGN ITTLKMFDRE ERSFYNIKII
ATDNSESALI PGKHNAGQQV FLIEIADKND NPPHFTQDTY VAESIAENAN INELVTQVTA
LDIDTASVVT YSIVAGNTYD AFVIRNFTGE IRVNNELDYE NITSYSLDVR AFDGLYEDYA
KVLIKIENLN DNPPVFLANY TKTIEEEKLY EGCIVKVEAY DPDLDRNEPQ NIVYSLVKHE
QKEFLQIDND GCLRLTKPLD RDQPSGFTRW QILIMAADHG GRLGSDSLRS TTEVILELTD
INDNAPFLTN TQPIIWYENE PPGQVVILTA KDYDSAENGP PFTFALNESA SFDIRSKFHI
QGNILSTLVS FDREQRKEYK IPVAITDSGT PRLTGVSILH IVIGDRNDNS MEPGHSDIFV
YNYKGEAPDT EIGRVFVNDP DDWDLPDKRF MWLPSYEQRS PYFDVHSNTG MITMKEGTPN
GTYMLRFNVT EVNEPLVPFH WVEATVNVTI KEIPEEAVDK SGSIRFLNIT AEEFIIPEAD
GTSKKDKLHR RLAELYNKSM DNVDVFTVFT KLTVKDAFLD VRFSAHGSPY FEAEKLDSMV
VGIQEKLEDE LGVRIYMVKI DECLIEKEQC EDSCRNVLIK NNVPLSVYTN TTSFVGVSAR
VESECTCDVE EPLICLNGGT PFADKCECPE GWNGPHCEQT SIGFHGDGWA MYPSPPACHE
GHVTLTVTSH TSNALVFYLG PLKFNPLLDV QDFMSLELVD GYPILLVNYG SGTTRLNNSV
VHVADGKPHL IEIVLMRSSI EMFVDRCKLS TCMSLAAPTG PREILNVNGP LQLGGASVDL
QSLARSFGWR YVPTNQHFMG CISNFTYNDY MYNLGKPSVE RNADPGCQKS VFTAVTFGID
TNFLVAILVC IAILIILLLA VVVHRKRADA WAEKELDDIR ENIIAYEDEG GGEGDAGYDL
HVLRQMYDGP PPDNEPAFMH VPVVGAAPDI SGFLDDKKSV LDRDPDINPY DDVRHYAYEG
DGNTSGSLSS LASCTDDEDL KFNYLSTFGP RFRKLADMYG DDGEDRQHEE SWC
//
