ID A0A212FA75_DANPL Unreviewed; 468 AA.
AC A0A212FA75;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Coiled-coil domain-containing protein 49 {ECO:0000313|EMBL:OWR50628.1};
DE SubName: Full=Pre-mRNA-splicing factor CWC25 homolog {ECO:0000313|RefSeq:XP_032529494.1};
GN Name=LOC116779348 {ECO:0000313|RefSeq:XP_032529494.1};
GN ORFNames=KGM_211174 {ECO:0000313|EMBL:OWR50628.1};
OS Danaus plexippus plexippus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Nymphalidae; Danainae; Danaini; Danaina; Danaus; Danaus.
OX NCBI_TaxID=278856 {ECO:0000313|EMBL:OWR50628.1, ECO:0000313|Proteomes:UP000007151};
RN [1] {ECO:0000313|EMBL:OWR50628.1, ECO:0000313|Proteomes:UP000007151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F-2 {ECO:0000313|EMBL:OWR50628.1};
RX PubMed=22118469; DOI=10.1016/j.cell.2011.09.052;
RA Zhan S., Merlin C., Boore J.L., Reppert S.M.;
RT "The monarch butterfly genome yields insights into long-distance
RT migration.";
RL Cell 147:1171-1185(2011).
RN [2] {ECO:0000313|EMBL:OWR50628.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=F-2 {ECO:0000313|EMBL:OWR50628.1};
RA Zhan S., Reppert S.M.;
RT "MonarchBase: the monarch butterfly genome database.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:XP_032529494.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the CWC25 family.
CC {ECO:0000256|ARBA:ARBA00006695}.
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DR EMBL; AGBW02009514; OWR50628.1; -; Genomic_DNA.
DR RefSeq; XP_032529494.1; XM_032673603.1.
DR STRING; 278856.A0A212FA75; -.
DR EnsemblMetazoa; XM_032673603.1; XP_032529494.1; LOC116779348.
DR KEGG; dpl:KGM_211174; -.
DR eggNOG; KOG3869; Eukaryota.
DR OrthoDB; 12277at2759; -.
DR Proteomes; UP000007151; Unassembled WGS sequence.
DR Proteomes; UP000596680; Chromosome 5.
DR GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR InterPro; IPR019339; CIR_N_dom.
DR InterPro; IPR022209; CWC25.
DR PANTHER; PTHR16196; CELL CYCLE CONTROL PROTEIN CWF25; 1.
DR PANTHER; PTHR16196:SF0; PRE-MRNA-SPLICING FACTOR CWC25 HOMOLOG; 1.
DR Pfam; PF10197; Cir_N; 1.
DR Pfam; PF12542; CWC25; 1.
DR SMART; SM01083; Cir_N; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW mRNA processing {ECO:0000256|ARBA:ARBA00022664};
KW mRNA splicing {ECO:0000256|ARBA:ARBA00023187};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000007151};
KW Spliceosome {ECO:0000256|ARBA:ARBA00022728}.
FT DOMAIN 11..47
FT /note="CBF1-interacting co-repressor CIR N-terminal"
FT /evidence="ECO:0000259|SMART:SM01083"
FT REGION 1..69
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 209..468
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 27..55
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 224..241
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 242..256
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 265..325
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 332..389
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 404..418
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 427..443
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 444..468
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 468 AA; 54361 MW; 131CFB829DDEB77B CRC64;
MGGGDLNTKK AWHPSNLKNQ ERVWKAEQAA AAEKKRIEEL ERERAQERDR EELNALSRQN
VNTNTTQENR LHWMYDKPDK QVQQEDYLLG KAIDKNYDQG DKQDQNEIPA VSRRVVGSSM
MTAGGDVQVD LARKLREDPL LLVKERERAA RAALLNNPIQ RRKLTELLRK EQEKKILKKK
SKKSNIDELL ASKLSALAGE KSMNLAKLLD SDSSSSDSSS SSSRKKKTKK KKKKMSKHKS
KKHQGSDSDE KQEKSKKSKD KKKHKDRKDK NDDSDAGTIS KREKYHNDLK FDDKKYPSSM
KRKSHVDSDG EPQRKSRKSL KEVSPYQKRN ESYSQDRYRR SSGDRNRSRR ETENDDRRNS
DRRGPSRSRS RYDQKTPRDN QRSELSQDEK AAKLAAMVQA GAEREIQRGR RVAEQLAEKA
AEDTTTLPRS SHKNQARTLP DSLESRIHSN RHNIQRDKRH MNEHFARR
//
