ID A0A212FDY0_DANPL Unreviewed; 1028 AA.
AC A0A212FDY0;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Multiple epidermal growth factor domains 10 {ECO:0000313|EMBL:OWR51934.1};
DE SubName: Full=Protein draper isoform X2 {ECO:0000313|RefSeq:XP_032512794.1};
GN Name=LOC116766796 {ECO:0000313|RefSeq:XP_032512794.1};
GN ORFNames=KGM_208973 {ECO:0000313|EMBL:OWR51934.1};
OS Danaus plexippus plexippus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Nymphalidae; Danainae; Danaini; Danaina; Danaus; Danaus.
OX NCBI_TaxID=278856 {ECO:0000313|EMBL:OWR51934.1, ECO:0000313|Proteomes:UP000007151};
RN [1] {ECO:0000313|EMBL:OWR51934.1, ECO:0000313|Proteomes:UP000007151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F-2 {ECO:0000313|EMBL:OWR51934.1};
RX PubMed=22118469; DOI=10.1016/j.cell.2011.09.052;
RA Zhan S., Merlin C., Boore J.L., Reppert S.M.;
RT "The monarch butterfly genome yields insights into long-distance
RT migration.";
RL Cell 147:1171-1185(2011).
RN [2] {ECO:0000313|EMBL:OWR51934.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=F-2 {ECO:0000313|EMBL:OWR51934.1};
RA Zhan S., Reppert S.M.;
RT "MonarchBase: the monarch butterfly genome database.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:XP_032512794.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
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DR EMBL; AGBW02008996; OWR51934.1; -; Genomic_DNA.
DR RefSeq; XP_032512794.1; XM_032656903.1.
DR STRING; 278856.A0A212FDY0; -.
DR EnsemblMetazoa; XM_032656903.1; XP_032512794.1; LOC116766796.
DR KEGG; dpl:KGM_208973; -.
DR eggNOG; KOG1218; Eukaryota.
DR Proteomes; UP000007151; Unassembled WGS sequence.
DR Proteomes; UP000596680; Chromosome 8.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0005044; F:scavenger receptor activity; IEA:InterPro.
DR GO; GO:0048513; P:animal organ development; IEA:UniProt.
DR GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR GO; GO:0048731; P:system development; IEA:UniProt.
DR CDD; cd00055; EGF_Lam; 2.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR Gene3D; 2.170.300.10; Tie2 ligand-binding domain superfamily; 4.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR011489; EMI_domain.
DR InterPro; IPR002049; LE_dom.
DR InterPro; IPR042635; MEGF10/SREC1/2-like.
DR PANTHER; PTHR24043:SF8; EGF-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR24043; SCAVENGER RECEPTOR CLASS F; 1.
DR Pfam; PF00053; Laminin_EGF; 6.
DR PRINTS; PR00011; EGFLAMININ.
DR SMART; SM00181; EGF; 15.
DR SMART; SM00180; EGF_Lam; 14.
DR PROSITE; PS00022; EGF_1; 11.
DR PROSITE; PS01186; EGF_2; 1.
DR PROSITE; PS50026; EGF_3; 9.
DR PROSITE; PS50027; EGF_LAM_2; 1.
DR PROSITE; PS51041; EMI; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Laminin EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00460};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007151};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..1028
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041057748"
FT TRANSMEM 793..817
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 20..97
FT /note="EMI"
FT /evidence="ECO:0000259|PROSITE:PS51041"
FT DOMAIN 139..169
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 177..212
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 260..295
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 303..338
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 392..427
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 435..470
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 443..490
FT /note="Laminin EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50027"
FT DOMAIN 483..513
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 565..600
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 696..731
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT REGION 987..1028
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1009..1028
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT DISULFID 159..168
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 202..211
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 285..294
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 328..337
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 417..426
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 460..469
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 503..512
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 590..599
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
FT DISULFID 721..730
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 1028 AA; 110843 MW; D1F8635FF196FB4E CRC64;
MLTAGVLVFL AASVSALLEG PNVCTKQESY TTVIRVSAQQ PYQVKEYAWC FNVPPRCSKY
NIKFKQVFKT QKLIKQRPIE QCCDGYAPDP EGRQCVPVCV EACVHGKCVA PNTCACAHRY
GGPACDISCP DGKWGRNCQN ECRCMHGGSC EPLTGDCACA VGWWGDACEK ACAPPTFGQN
CEQICACKNN GTCDPASGAC TCPREFTGPL CEKECPKNDI CPLSCLCQND AKCNLFTGDC
ECTPGWTGEV CANKCPAGRW GDKCSRTCEC WNGASCHHVT GQCQCEAGFT GDKCLESCPL
GTYGVSCAGV CKCQHGGECS PKDGSCTCKP GWQGDRCERR ACPNGLWGPR CDKTCECNPT
TTDMCDPWTG ACECAAGWAG ESCARQCPLL TYGKGCRSSC RCENSGHCSP VNGSCLCAPG
YRGLRCEEPC PYPFYGDNCA DTCDCRNNAS CSHETGQCDC KPGFDGLKCD RPCDGKTFGL
RCRQPCNCEN DAPCNPVNGE CVCGPGYEGP RCERRCRAGY YGQNCSFPCD CTENAVGCHH
VTGACVCESS WRGIRCETQC EAGQYGVQCS EKCPCANNSS CDAESGRCEC APGWRGERCD
VPCEPGTYGA ACKQLCPHHP LGNVTCNPTT GEYSCASGYT GVSCEYPCPL GTYGEGCQQK
CNCKNGADCH HVTGECQCLP GWRGSLCGEA CPPGWWGAGC SQPCRCARGA ACRPNDGYCR
CPPGYTGNYC TQFCPEGYFG DHCMEACNCS SHGNWVCEPV RGCVCHRGFV GENCDLRASD
AIVIDQARGS SNAGLTAVML VAVIACGAAA VLVLLYYRRR VRSLKREIAH VHYTADPNTQ
PDQQHFDNPV YSFQNSTRSD DSTTLLNNST IFNNLDNSSK ISNAALEKLR MTASSSNGTY
DPFSSIKNKD ADMTNPNLYH CIEDDNKLDH VYDEIKHKEG YEMEYDHLNY TPPANTWKPH
YVRMNGSIGG GQTSTPPIPP LPKLHTAVPI VPGPQVQGPL EPGEPSVLSD NEAPPPPPTR
EEPHEQPL
//
