ID A0A212FGU0_DANPL Unreviewed; 1596 AA.
AC A0A212FGU0;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 24-JAN-2024, entry version 21.
DE RecName: Full=DENN domain-containing protein Crag {ECO:0008006|Google:ProtNLM};
GN ORFNames=KGM_202137 {ECO:0000313|EMBL:OWR52923.1};
OS Danaus plexippus plexippus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Nymphalidae; Danainae; Danaini; Danaina; Danaus; Danaus.
OX NCBI_TaxID=278856 {ECO:0000313|EMBL:OWR52923.1, ECO:0000313|Proteomes:UP000007151};
RN [1] {ECO:0000313|EMBL:OWR52923.1, ECO:0000313|Proteomes:UP000007151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F-2 {ECO:0000313|EMBL:OWR52923.1};
RX PubMed=22118469; DOI=10.1016/j.cell.2011.09.052;
RA Zhan S., Merlin C., Boore J.L., Reppert S.M.;
RT "The monarch butterfly genome yields insights into long-distance
RT migration.";
RL Cell 147:1171-1185(2011).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWR52923.1}.
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DR EMBL; AGBW02008606; OWR52923.1; -; Genomic_DNA.
DR STRING; 278856.A0A212FGU0; -.
DR KEGG; dpl:KGM_202137; -.
DR eggNOG; KOG2127; Eukaryota.
DR InParanoid; A0A212FGU0; -.
DR Proteomes; UP000007151; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR Gene3D; 2.100.10.50; -; 1.
DR Gene3D; 3.40.50.11500; -; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR001194; cDENN_dom.
DR InterPro; IPR005112; dDENN_dom.
DR InterPro; IPR043153; DENN_C.
DR InterPro; IPR023341; MABP.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR037516; Tripartite_DENN.
DR InterPro; IPR005113; uDENN_dom.
DR PANTHER; PTHR12296; DENN DOMAIN-CONTAINING PROTEIN 4; 1.
DR PANTHER; PTHR12296:SF30; DENN DOMAIN-CONTAINING PROTEIN CRAG; 1.
DR Pfam; PF03455; dDENN; 1.
DR Pfam; PF02141; DENN; 1.
DR Pfam; PF03456; uDENN; 1.
DR SMART; SM00801; dDENN; 1.
DR SMART; SM00799; DENN; 1.
DR SMART; SM00800; uDENN; 1.
DR PROSITE; PS50211; DENN; 1.
DR PROSITE; PS51498; MABP; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000007151};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 735..752
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 772..793
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 36..192
FT /note="MABP"
FT /evidence="ECO:0000259|PROSITE:PS51498"
FT DOMAIN 184..635
FT /note="UDENN"
FT /evidence="ECO:0000259|PROSITE:PS50211"
FT REGION 519..540
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 944..988
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1015..1035
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1055..1088
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1228..1247
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 101..128
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 519..533
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1596 AA; 177535 MW; 3CBF4488C87E6561 CRC64;
MDERRVADYF VVAGLPEVPE ILDDSDSGHL KGYSTRAPIT DIGVMFPGLG EKVPDGYEML
ELTPTGLPAD LNHGSMRSPE CFLCIRRGRD RPPLVDIGVM YEGKERLMAD AEMVLRSVED
RVANVNNSSA KTFITYRRAH PNAPCNALVV VDVCVIVESR GETPPHAFCM IPKNLNKGLM
GSNVFLCYKK SMNRPPLIAY KPEVLFRYPQ VDRRSLAFPT SVPLFCLPMG ATLEVWPNNA
SSPKPVFSTF VLTVADATDK VYGSAVTFYE RYTSPLSESQ MDQLGWRAGV THMTHSLHAN
KSICLLSRWP FSDTFERWLL YILEMSWSKE PLNIPIERYI THLLEEVPFP EPRILLQLSP
TNPHDRVIVT RRDDQPLVRS GAGFRQLLLN LGPDNCLLLL ALAITEQKIL IHSLRPDTLT
AVSEAVSSFL FPFKWQCPYI PLCPLGLAEV LHAPLPYLIG VDSRFFDLYE PPPDVTCVDL
DTNNITICES QRHISLKLLP KRQARVLRQT LDQLLSNIRP ASPVNSSGDK HNGEPTTSLD
RDFQKRKKEQ ALELKIQEAF LRFMAVTFQG YRSFLIPITK APTVGTTDPH ALFHMDSFLR
SRDKTHQRFF ALTMRTQMFT RFIEERSFVC DADQALSFFD ECIERVASEE PLLGMDDSNT
SERTVFVLPP DPPDTEQQYT YNKFILDEQL VSLCHSTRGS LTCAPAAALA SVESLADASP
MARRTKQEIA AAQRIMYIYI YIYIYITLRF AFELLERATK LRVPCDEVCY RVMMQLCGIH
SLPVLAVQLL FLMKRAGLQP NALTYGYYNR CVLEAAWHKD MPSGSQLMWN KVRIAIMGVT
LFRKAGALRA SRAAGAAGST GTLPRVRTVG GEGADLTALA LAEPTRSRCS LDSACDLNAS
VSTNTASTTA FEALYCRGNI VRAPASHPRA HQISSTAGIL ISGLPSDPDL SSTTRPRSNS
LGSEEVESSV SITEKRQTIH VSPDSPSDLR ILTRSESFAG DAQIVQNLQR LSFSSSTSNT
KSRCSRTLSF PEEPEKETAL VDKVEKTISS PLKVSPRTPV LADDPLGALS VEPSSPAPAP
PTTDVPLPRH ELSVSPRLFQ RSNSFTEEPE TVGKLHRSET APATVSSSLA SIGNTLKISF
GRYSPARLSL RKDNMNIGKA MIENYFSPTS IAGKKSNELL QSGLSSLKSA ATSMAKKFDE
MKEVISANST PVKGAIGNAT SALTNFRGDD DSGDGSSEVN QNEWSGGVGF RRASSDAELA
CSMERGSLAT LLSHLPDNLY PTQYDNSKSE NPSVEVRMTS CSQCHQCLAL LYDEDIMAGW
AADDSNLNTR CTACGRHTVP LLSVQVRYTE VIVRMDQTQA ETLTVPYLNP LVLRKEFESI
LGREGDACLA EREFVESHPI VYWNLVWFLE RANIDNHFPD LLCPNFSVKY QSSDPLPDVD
KMTVGCRVVC SWEGARAADC EAPSLHRAWR ARRTQPRSRQ LRALLLSHHD RPTDSIVATI
LDGLMSNDLS DAVRKLAAWR ESTCANKRYH SYYRDILFLA MAALGEQKIN VTVFQREYTR
AIEQLGTEAR PQDLPPSPTA VCCRHYFKRL TLDVDD
//
