ID A0A212FLH9_DANPL Unreviewed; 865 AA.
AC A0A212FLH9;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Brain tumor protein {ECO:0000313|EMBL:OWR54608.1, ECO:0000313|RefSeq:XP_032512283.1};
GN Name=LOC116766513 {ECO:0000313|RefSeq:XP_032512283.1};
GN ORFNames=KGM_213274 {ECO:0000313|EMBL:OWR54608.1};
OS Danaus plexippus plexippus.
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Papilionoidea;
OC Nymphalidae; Danainae; Danaini; Danaina; Danaus; Danaus.
OX NCBI_TaxID=278856 {ECO:0000313|EMBL:OWR54608.1, ECO:0000313|Proteomes:UP000007151};
RN [1] {ECO:0000313|EMBL:OWR54608.1, ECO:0000313|Proteomes:UP000007151}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=F-2 {ECO:0000313|EMBL:OWR54608.1};
RX PubMed=22118469; DOI=10.1016/j.cell.2011.09.052;
RA Zhan S., Merlin C., Boore J.L., Reppert S.M.;
RT "The monarch butterfly genome yields insights into long-distance
RT migration.";
RL Cell 147:1171-1185(2011).
RN [2] {ECO:0000313|EMBL:OWR54608.1}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=F-2 {ECO:0000313|EMBL:OWR54608.1};
RA Zhan S., Reppert S.M.;
RT "MonarchBase: the monarch butterfly genome database.";
RL Submitted (OCT-2012) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:XP_032512283.1}
RP IDENTIFICATION.
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
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DR EMBL; AGBW02007761; OWR54608.1; -; Genomic_DNA.
DR RefSeq; XP_032512283.1; XM_032656392.1.
DR STRING; 278856.A0A212FLH9; -.
DR EnsemblMetazoa; XM_032656392.1; XP_032512283.1; LOC116766513.
DR KEGG; dpl:KGM_213274; -.
DR eggNOG; KOG2177; Eukaryota.
DR OrthoDB; 5387006at2759; -.
DR Proteomes; UP000007151; Unassembled WGS sequence.
DR Proteomes; UP000596680; Chromosome 7.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0060255; P:regulation of macromolecule metabolic process; IEA:UniProt.
DR CDD; cd19813; Bbox1_BRAT-like; 1.
DR CDD; cd14959; NHL_brat_like; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR003649; Bbox_C.
DR InterPro; IPR001258; NHL_repeat.
DR InterPro; IPR047153; TRIM45/56/19.
DR InterPro; IPR000315; Znf_B-box.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR25462; BONUS, ISOFORM C-RELATED; 1.
DR PANTHER; PTHR25462:SF276; MEIOTIC P26, ISOFORM F; 1.
DR Pfam; PF01436; NHL; 2.
DR SMART; SM00502; BBC; 1.
DR SMART; SM00336; BBOX; 2.
DR SMART; SM00184; RING; 2.
DR SUPFAM; SSF57845; B-box zinc-binding domain; 1.
DR SUPFAM; SSF63829; Calcium-dependent phosphotriesterase; 1.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR PROSITE; PS51125; NHL; 2.
DR PROSITE; PS50119; ZF_BBOX; 2.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000007151};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00024}.
FT DOMAIN 34..82
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 112..159
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT DOMAIN 172..215
FT /note="B box-type"
FT /evidence="ECO:0000259|PROSITE:PS50119"
FT REPEAT 596..639
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT REPEAT 643..689
FT /note="NHL"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00504"
FT COILED 247..304
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 865 AA; 93334 MW; 1AAF371C2697AC10 CRC64;
MEEINGELFG DGLVSLGDEG SLESTDTGKQ EQNCKLCDNK LCSPRVLSCL HVFCEACIDK
LMVNEAGDSL KYDLAVECPL CKQETKVMPG GGAASLPSDY VLTNILDVSA MDQSVVCTCC
KSKEPAVARC TDCSHFLCSN CNSAHEFMRC FENHRVVPFD ALRSSKEKAA VHKPIFCTRH
VGESLKYYCC ECEVGACTEC LTVDHKVGEH RCERIVDAEP NLRAELRNFI VEANARAVAA
GSASARLDDA LGDLQRQRDD AESVINEAYH AYKAALERRR DKALEELERL HKERELKVMD
LFDRVDKTVQ RIDCACKFAA RLLRRGDGTE IVMLKKTVAS QFARLLEGAP EFDIDYSLEY
VTKMDKFDAI TEETFGTFRT EATRAEERKR ASESSAIVSV ASNSHSPAVS VTNAPVFDDF
PLGNVRRVTG GVGSMVGVGV PSIGVPGVGP VTGVANSGVL PGVVGVNSVG VGGVSGVPAL
PSMVEYNLQQ LASIAEKEVP PPPHASPAPS FTLAELLAGD LNSPQAYNNL QALAKLGLNT
EVNGFGGVGG VGGLGGVGPR GVSPGRPLLT AAEEAALVAP PAPLVRATKA TPMHIRFKFG
QLGGGKGQFN SPHGFCLGND EDIIVADTNN HRITVFDKSG THKFNFGVAG KEEGQLWYPR
KVAVVRATGK FVVCDRGNER SRMQIFTKNG HFLKKIAVRF IDIVAGLAVT AEGLIVAVDS
VTPTVFILSE EGDLLSWFDC SECMREPSDI AISGKEFYVC DFKGHCVVVF DDEGRFLRRI
GCENVTNFPN GIDVSDAGDV LIGDSHGNKF HVAVFSRDGV LVTEFECPYV KVSRCCGLKI
TSEGYIVTLA KNNHHVLVLN TLYIV
//
