ID A0A212QSC2_9CHLR Unreviewed; 484 AA.
AC A0A212QSC2;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=Multisubunit sodium/proton antiporter, MrpD subunit {ECO:0000313|EMBL:SNB62507.1};
GN ORFNames=SAMN02746019_00005350 {ECO:0000313|EMBL:SNB62507.1};
OS Thermoflexus hugenholtzii JAD2.
OC Bacteria; Chloroflexota; Thermoflexia; Thermoflexales; Thermoflexaceae;
OC Thermoflexus.
OX NCBI_TaxID=877466 {ECO:0000313|EMBL:SNB62507.1, ECO:0000313|Proteomes:UP000197025};
RN [1] {ECO:0000313|Proteomes:UP000197025}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=JAD2 {ECO:0000313|Proteomes:UP000197025};
RA Varghese N., Submissions S.;
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|RuleBase:RU000320}; Multi-
CC pass membrane protein {ECO:0000256|RuleBase:RU000320}.
CC -!- SIMILARITY: Belongs to the CPA3 antiporters (TC 2.A.63) subunit D
CC family. {ECO:0000256|ARBA:ARBA00005346}.
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DR EMBL; FYEK01000022; SNB62507.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A212QSC2; -.
DR InParanoid; A0A212QSC2; -.
DR OrthoDB; 9811718at2; -.
DR Proteomes; UP000197025; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008137; F:NADH dehydrogenase (ubiquinone) activity; IEA:InterPro.
DR GO; GO:0042773; P:ATP synthesis coupled electron transport; IEA:InterPro.
DR InterPro; IPR003918; NADH_UbQ_OxRdtase.
DR InterPro; IPR001750; ND/Mrp_mem.
DR PANTHER; PTHR42703:SF1; NA(+)_H(+) ANTIPORTER SUBUNIT D1; 1.
DR PANTHER; PTHR42703; NADH DEHYDROGENASE; 1.
DR Pfam; PF00361; Proton_antipo_M; 1.
DR PRINTS; PR01437; NUOXDRDTASE4.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|RuleBase:RU000320, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 6..24
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 31..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 72..95
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 107..126
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..150
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 162..183
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..226
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 238..257
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 304..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 371..393
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 405..427
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 447..473
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 128..418
FT /note="NADH:quinone oxidoreductase/Mrp antiporter membrane
FT subunit"
FT /evidence="ECO:0000259|Pfam:PF00361"
SQ SEQUENCE 484 AA; 51778 MW; A167575142ADBBEF CRC64;
MGLWLILPIL IPFLSAVATL LAWGQRPFQR AMGVLGTAGL LGAGVMLLDS VWRDGVQTLQ
VGNWPAPFGI TLYADLFSAA MVILAGLIGL AVAVYSLGSM DPDREQFGYY AIFHILLMGV
CGAFLTGDIF NLYVWFEVML IASFVLMVLG GERAQLEGGI KYVTLNLMAS ALFLAAVGIL
YGVTGTLNMA DLAHRLGRVS SPGLMTALAL MFLVAFGIKA AVFPLFFWLP ASYHTPPVAV
SALFSGLLTK VGVYALIRVF TRLFVQDVGY THTLILIIAG LTMVTGVLGA VAQMEVRRIL
SFHIISQIGY MVMGLGMLTP LALGGAIFYI IHHIIVKTNL FLISGMVLHL RGTHQLKNLG
GLYRAHPGVS FLFLIPALSL AGLPPLSGFF AKLALVRAGL EAGQFAIVAV ALGVSLLTLF
SMMKIWNEAF WKPSGEDDPP PTRSVPTALW LPTAGLALLT ILIGLAAGPL LVFSMRAAEQ
LLGM
//
