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Database: UniProt
Entry: A0A212R2Q9_9CHLR
LinkDB: A0A212R2Q9_9CHLR
Original site: A0A212R2Q9_9CHLR 
ID   A0A212R2Q9_9CHLR        Unreviewed;       229 AA.
AC   A0A212R2Q9;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 24.
DE   RecName: Full=Manganese transport regulator {ECO:0000256|ARBA:ARBA00032593};
GN   ORFNames=SAMN02746019_00000920 {ECO:0000313|EMBL:SNB66293.1};
OS   Thermoflexus hugenholtzii JAD2.
OC   Bacteria; Chloroflexota; Thermoflexia; Thermoflexales; Thermoflexaceae;
OC   Thermoflexus.
OX   NCBI_TaxID=877466 {ECO:0000313|EMBL:SNB66293.1, ECO:0000313|Proteomes:UP000197025};
RN   [1] {ECO:0000313|Proteomes:UP000197025}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JAD2 {ECO:0000313|Proteomes:UP000197025};
RA   Varghese N., Submissions S.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Homodimer. {ECO:0000256|ARBA:ARBA00011738}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the DtxR/MntR family.
CC       {ECO:0000256|ARBA:ARBA00007871}.
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DR   EMBL; FYEK01000028; SNB66293.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A212R2Q9; -.
DR   InParanoid; A0A212R2Q9; -.
DR   OrthoDB; 9791355at2; -.
DR   Proteomes; UP000197025; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0046914; F:transition metal ion binding; IEA:InterPro.
DR   Gene3D; 2.30.30.90; -; 1.
DR   Gene3D; 1.10.60.10; Iron dependent repressor, metal binding and dimerisation domain; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR007167; Fe-transptr_FeoA.
DR   InterPro; IPR001367; Fe_dep_repressor.
DR   InterPro; IPR036421; Fe_dep_repressor_sf.
DR   InterPro; IPR038157; FeoA_core_dom.
DR   InterPro; IPR022687; HTH_DTXR.
DR   InterPro; IPR022689; Iron_dep_repressor.
DR   InterPro; IPR008988; Transcriptional_repressor_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR33238; IRON (METAL) DEPENDENT REPRESSOR, DTXR FAMILY; 1.
DR   PANTHER; PTHR33238:SF7; TRANSCRIPTIONAL REGULATOR MNTR; 1.
DR   Pfam; PF02742; Fe_dep_repr_C; 1.
DR   Pfam; PF01325; Fe_dep_repress; 1.
DR   Pfam; PF04023; FeoA; 1.
DR   SMART; SM00899; FeoA; 1.
DR   SMART; SM00529; HTH_DTXR; 1.
DR   SUPFAM; SSF50037; C-terminal domain of transcriptional repressors; 1.
DR   SUPFAM; SSF47979; Iron-dependent repressor protein, dimerization domain; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50944; HTH_DTXR; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          1..58
FT                   /note="HTH dtxR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50944"
FT   REGION          210..229
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        212..229
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   229 AA;  25595 MW;  2FF864F83594D868 CRC64;
     MEDYLRAIYI LAEREGVVST TRLAEYLNVS PPSVTGMLKK LARLRLVHYT PYRGVALTRA
     GRRIALEVIR HHRLLELFLM EALGYDWDEV HAEADRLEHA ISEALEERIA TLLGHPAYDP
     HGDPIPTRSG EIPAPLACRL SEAPLGVACE VLRVTDEVST LRQAARVGLR PGTRVTVEEQ
     EPGAGLRIRV GDQTHRIRRR LADRIFVRVP IPEPTEEPPP DAATPSDHP
//
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