ID A0A212S4U1_RHOAC Unreviewed; 836 AA.
AC A0A212S4U1;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=SAMN06265338_11292 {ECO:0000313|EMBL:SNB80203.1};
OS Rhodoblastus acidophilus (Rhodopseudomonas acidophila).
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Hyphomicrobiales;
OC Beijerinckiaceae; Rhodoblastus.
OX NCBI_TaxID=1074 {ECO:0000313|EMBL:SNB80203.1, ECO:0000313|Proteomes:UP000198418};
RN [1] {ECO:0000313|Proteomes:UP000198418}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 137 {ECO:0000313|Proteomes:UP000198418};
RA Varghese N., Submissions S.;
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
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DR EMBL; FYDG01000012; SNB80203.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A212S4U1; -.
DR OrthoDB; 9797304at2; -.
DR Proteomes; UP000198418; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 1.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43711:SF1; HISTIDINE KINASE 1; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF12860; PAS_7; 2.
DR Pfam; PF13188; PAS_8; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SMART; SM00091; PAS; 3.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000198418};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 51..72
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 602..819
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
SQ SEQUENCE 836 AA; 92932 MW; 6F54873EFE465BA0 CRC64;
MRKRKRHSTP LKRAASRVLR SASLAMIAMP MAARAESLID FAQAEETHGL IRLSAGAGLV
IFSAITIFFH LAGRQAWRKR ELELQAEVDR LRQQADRARS FSASDSQFVV VWAGSSNEPE
IEGDISLALD APLPRRILGF NTWLSADQAS AMEANVSRLR ERGQGFRLDL VSHNGRHLEA
EGRAIGSRAV LRVRDVSGDR LELMRLRALH AEQTSQLEIL RSLLDVSSHP IWTRNGAGVL
TWVNDAYCRA VEAKDRRDVA ARNLELLDSQ SREQAARARE AGQPWRVRRN VVVAGERKLM
EVLDASLSGG SGGVAYDLSE LEGLRADHAR QMDSHIRTLD QIATAIAIFD RTKNLVFANA
AYRQLWGLEQ AFLDQKPSDS EILERLRAER RLPEQADFRS WKNSLLSLYH SLEPAPQVWH
LPDGRTIRVG FDPNPQGGLT YLFDDVTERF TLESQYNSLA RVQSETLDAL QEGVAVFGAD
GRLKFYNPSF GRMWRLPLNQ LTKKPHIDVI AQGCRSLVPE DAAWNDLRSI VTGLHAARMG
FERRMPRTDG SIVDCAAAPL PDGGTLLTFI DVTDGVNVER ALTERNQALE AAERLRDDFV
HHVSYELRSP LTNIIGFIQL LGDSSVGPLN EKQREYTNYV LKSSAALLAI INDILDLATI
DRDAMELRAE DVDIAKTIRE AAEGVQDRLA ECQVELSLVM PKDIGVFRAD SKRIRQILFN
LLSNAIGFSE PGQTVTLAAF RRADDIVFKV SDNGRGIPPD ILDKVFNRFE SHTLNSRHRG
VGLGLSIVRA FVEAHGGEVL IDSAPGEGTV VTCIFPIRGV RENGRQITGE KAEGLA
//
