ID   A0A212T200_9MICO        Unreviewed;       450 AA.
AC   A0A212T200;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 16.
DE   SubName: Full=HNH endonuclease {ECO:0000313|EMBL:SNC60078.1};
GN   ORFNames=SAMN05445756_0202 {ECO:0000313|EMBL:SNC60078.1};
OS   Kytococcus aerolatus.
OC   Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Kytococcaceae;
OC   Kytococcus.
OX   NCBI_TaxID=592308 {ECO:0000313|EMBL:SNC60078.1, ECO:0000313|Proteomes:UP000198122};
RN   [1] {ECO:0000313|EMBL:SNC60078.1, ECO:0000313|Proteomes:UP000198122}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 22179 {ECO:0000313|EMBL:SNC60078.1,
RC   ECO:0000313|Proteomes:UP000198122};
RA   Kim H.J., Triplett B.A.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the Rv1128c/1148c/1588c/1702c/1945/3466 family.
CC       {ECO:0000256|ARBA:ARBA00023450}.
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DR   EMBL; FYEZ01000001; SNC60078.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A212T200; -.
DR   Proteomes; UP000198122; Unassembled WGS sequence.
DR   GO; GO:0004519; F:endonuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd00085; HNHc; 1.
DR   Gene3D; 1.10.30.50; -; 1.
DR   InterPro; IPR003870; DUF222.
DR   InterPro; IPR002711; HNH.
DR   InterPro; IPR003615; HNH_nuc.
DR   Pfam; PF02720; DUF222; 1.
DR   Pfam; PF01844; HNH; 1.
DR   SMART; SM00507; HNHc; 1.
PE   3: Inferred from homology;
KW   Endonuclease {ECO:0000313|EMBL:SNC60078.1};
KW   Hydrolase {ECO:0000313|EMBL:SNC60078.1};
KW   Nuclease {ECO:0000313|EMBL:SNC60078.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198122}.
FT   DOMAIN          335..385
FT                   /note="HNH nuclease"
FT                   /evidence="ECO:0000259|SMART:SM00507"
FT   REGION          408..450
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   450 AA;  48677 MW;  9E8FD7575932ED5E CRC64;
     MDGMDQTAHE VVIQLRERLR ELGERCSGSP PGELVNLIRG LEALANTAAA VQLDAVRELT
     VAQRALDAEA GVDQEASDRA IASMIGLARR QSPHRGARDR NLAAVLRDEL PRTREAMLAG
     RGGRHHAETM ARHTVFLSRE DRGRVDEELG PRLDELSPRA LGKRACARAY ELDPEAHVRH
     AALEHAQRRV SMQPQPDTMA LVSAYLPMTQ AIALWGVLDR EARTLRAAGD ERSLDQLRAD
     ALVERITGLG RDEAPRIELQ LVMPAGGAFG AAALRKVAGD SRSPAVLTGG GPLPAPMARE
     LVRSSPEVRL RRLLADPEGG TIVARDARSR RFSQADRELL LARDQTCRTP WCDAPVRAAD
     HVVPWARGGE TVVENGQGLC QHCNNAKEHP GWDSKASLSV DGVQQGVAVS TPTGHRYASP
     TPRVRPADAS SGVDPSPDPP ADHPRTQEVA
//