ID   A0A212TIC3_9BACT        Unreviewed;       466 AA.
AC   A0A212TIC3;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Multidrug resistance efflux pump {ECO:0000313|EMBL:SNC65715.1};
GN   ORFNames=SAMN06265337_1366 {ECO:0000313|EMBL:SNC65715.1};
OS   Hymenobacter gelipurpurascens.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Hymenobacteraceae;
OC   Hymenobacter.
OX   NCBI_TaxID=89968 {ECO:0000313|EMBL:SNC65715.1, ECO:0000313|Proteomes:UP000198131};
RN   [1] {ECO:0000313|EMBL:SNC65715.1, ECO:0000313|Proteomes:UP000198131}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 11116 {ECO:0000313|EMBL:SNC65715.1,
RC   ECO:0000313|Proteomes:UP000198131};
RA   Kim H.J., Triplett B.A.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the membrane fusion protein (MFP) (TC 8.A.1)
CC       family. {ECO:0000256|ARBA:ARBA00009477}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; FYEW01000001; SNC65715.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A212TIC3; -.
DR   OrthoDB; 9760528at2; -.
DR   Proteomes; UP000198131; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 2.40.50.100; -; 1.
DR   InterPro; IPR039562; MFP_biotin_lipoyl_2.
DR   InterPro; IPR011053; Single_hybrid_motif.
DR   PANTHER; PTHR30386; MEMBRANE FUSION SUBUNIT OF EMRAB-TOLC MULTIDRUG EFFLUX PUMP; 1.
DR   PANTHER; PTHR30386:SF26; TRANSPORT PROTEIN COMB; 1.
DR   Pfam; PF13533; Biotin_lipoyl_2; 1.
DR   Pfam; PF13437; HlyD_3; 1.
DR   PRINTS; PR01490; RTXTOXIND.
DR   SUPFAM; SSF51230; Single hybrid motif; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils}; Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        32..52
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          72..104
FT                   /note="Membrane fusion protein biotin-lipoyl like"
FT                   /evidence="ECO:0000259|Pfam:PF13533"
FT   REGION          442..466
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          154..254
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        446..466
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   466 AA;  51900 MW;  1E458D8CB1C6231B CRC64;
     MPFAEHPLEE TDPLTAHFRS FKRVQTPRNG RVLARWLGGI GLAVLLAGFL PWTQNIRSNG
     QLTTLRPQDR PQTVPSTIAG RIASWRVREG QRVKQGDTLV VITEIKEKYF DPELLARTRE
     QLAAKISALE ENRGKTVALG SQQTALRAGL SVSLDKARNK VTQTRLKVNS DEAELRAANN
     DFDIARQQLA RQEELYKQGL KSLTELEQRR LKFQESTAKR QAVENKLGAS RQELTNAQLE
     LSSLQADYQD KLSKSESERR SAVAYQFDSE GQISKLRNEL ANLSIRSGYY HIQAPQDGYV
     VRALKQGIGE IVKEGEAILT VMPIAPALSA ELYVRPMDIP LLSVGRKVRL QFDGWPALVF
     TGWPGTSFGT FGGRVAVIDN IDSQGQYRIL VTPDPDLEPW PEPLRVGSGV YGWALLDDVP
     IWYELWRQLN GFPPDFVGAP SDKAKSGLAG KKEAKAADSG EEEEAK
//