ID   A0A212TQM6_9ACTN        Unreviewed;       484 AA.
AC   A0A212TQM6;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Cell division protein FtsI/penicillin-binding protein 2 {ECO:0000313|EMBL:SNC68328.1};
GN   ORFNames=SAMN06272741_2290 {ECO:0000313|EMBL:SNC68328.1};
OS   Streptomyces sp. 2114.4.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1938836 {ECO:0000313|EMBL:SNC68328.1, ECO:0000313|Proteomes:UP000198141};
RN   [1] {ECO:0000313|Proteomes:UP000198141}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2114.4 {ECO:0000313|Proteomes:UP000198141};
RA   Varghese N., Submissions S.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the transpeptidase family.
CC       {ECO:0000256|ARBA:ARBA00007171}.
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DR   EMBL; FYEY01000001; SNC68328.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A212TQM6; -.
DR   OrthoDB; 9766847at2; -.
DR   Proteomes; UP000198141; Unassembled WGS sequence.
DR   GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR   Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR   InterPro; IPR012338; Beta-lactam/transpept-like.
DR   InterPro; IPR001460; PCN-bd_Tpept.
DR   PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR   PANTHER; PTHR30627:SF24; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE PBPA; 1.
DR   Pfam; PF00905; Transpeptidase; 1.
DR   SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
PE   3: Inferred from homology;
KW   Cell cycle {ECO:0000313|EMBL:SNC68328.1};
KW   Cell division {ECO:0000313|EMBL:SNC68328.1}.
FT   DOMAIN          153..480
FT                   /note="Penicillin-binding protein transpeptidase"
FT                   /evidence="ECO:0000259|Pfam:PF00905"
SQ   SEQUENCE   484 AA;  50583 MW;  87E544F75A628FCF CRC64;
     MNKPLRRASI FCLALIVALM GWVTWLQGAK AGEYKEDPHN PRVAIGKYAA PLGNILVGGE
     PVTGSAATSS TLKYKRTYKD GPLYAPVTGF TSQIFGHNQL ESLYGDLLDG SDSRLQSPAD
     ALTRTRAKGG DVATTIDPAV QKAGYRALDG KKGAAVAMDP DTGRILGMVS TPSYDPGTFA
     GSAGSDQKAW QKMSADPDHP EVNRALRQPL PPGSTFKLVV AAAALENGLY SSVDEPTHSP
     DPYTLPHTRT KLTNENRAAP CKNADIRTAL QYSCNTVFAK MAVDLGKDKV KAQAEKFGFN
     DEKVDTPVRA GKSVYPSDMD EAQTALSGIG QFDDQATPLQ MAMVSSALAN GGELKKPQLA
     DKLTDGGGNT VQDFGPAAYR GGKAVSAHTA GQLKSAMRTV VDKGTGSGAK IGGLTVGGKT
     GTAQHGVDNN GTPYAWFVSY AEDGKGHRVA VAVMVEDGHA ARNEVSGNGL AAPAARAMMK
     AALA
//