ID A0A212U2Y8_9ACTN Unreviewed; 257 AA.
AC A0A212U2Y8;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=DNA-binding transcriptional regulator, AcrR family {ECO:0000313|EMBL:SNC72608.1};
GN ORFNames=SAMN06272741_5682 {ECO:0000313|EMBL:SNC72608.1};
OS Streptomyces sp. 2114.4.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1938836 {ECO:0000313|EMBL:SNC72608.1, ECO:0000313|Proteomes:UP000198141};
RN [1] {ECO:0000313|Proteomes:UP000198141}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2114.4 {ECO:0000313|Proteomes:UP000198141};
RA Varghese N., Submissions S.;
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; FYEY01000001; SNC72608.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A212U2Y8; -.
DR Proteomes; UP000198141; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:UniProt.
DR Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR InterPro; IPR039538; BetI_C.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001647; HTH_TetR.
DR InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR PANTHER; PTHR30055:SF164; TRANSCRIPTIONAL REPRESSOR MCE3R; 1.
DR Pfam; PF13977; TetR_C_6; 1.
DR Pfam; PF00440; TetR_N; 1.
DR PRINTS; PR00455; HTHTETR.
DR SUPFAM; SSF46689; Homeodomain-like; 1.
DR SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR PROSITE; PS50977; HTH_TETR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335,
KW ECO:0000313|EMBL:SNC72608.1}; Repressor {ECO:0000256|ARBA:ARBA00022491};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 65..125
FT /note="HTH tetR-type"
FT /evidence="ECO:0000259|PROSITE:PS50977"
FT DNA_BIND 88..107
FT /note="H-T-H motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
FT REGION 45..68
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 257 AA; 28628 MW; 2AAB8AE28A209087 CRC64;
MGKERDEMKA ARGSVCRMCT AAVPAPGRGR PALYCSRSCQ AKAYRRRKQQ PVPAAERPAA
PGTPSPRRRQ IAEALWRIAA ERGLHAASLR EVAAEAGVSL RAVQYHFASK HRLLVDALQL
LHEENERIAR SRIRFDTTDP RALLRAVLDE FLPVDAQRTT ALRVFAAYYA RSLTDPELAE
VFLPADQPLE RLVAELIAAA QRDGRTAPGL DPWREADLLV SGAVGLGQDV LHRRRTLEDV
RRTLDYHLDK IFAGKPC
//
