ID   A0A212UH32_9BACT        Unreviewed;       570 AA.
AC   A0A212UH32;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Type I phosphodiesterase / nucleotide pyrophosphatase {ECO:0000313|EMBL:SNC77374.1};
GN   ORFNames=SAMN06265337_3957 {ECO:0000313|EMBL:SNC77374.1};
OS   Hymenobacter gelipurpurascens.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Hymenobacteraceae;
OC   Hymenobacter.
OX   NCBI_TaxID=89968 {ECO:0000313|EMBL:SNC77374.1, ECO:0000313|Proteomes:UP000198131};
RN   [1] {ECO:0000313|EMBL:SNC77374.1, ECO:0000313|Proteomes:UP000198131}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 11116 {ECO:0000313|EMBL:SNC77374.1,
RC   ECO:0000313|Proteomes:UP000198131};
RA   Kim H.J., Triplett B.A.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; FYEW01000003; SNC77374.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A212UH32; -.
DR   OrthoDB; 9766127at2; -.
DR   Proteomes; UP000198131; Unassembled WGS sequence.
DR   GO; GO:0004035; F:alkaline phosphatase activity; IEA:InterPro.
DR   CDD; cd16016; AP-SPAP; 1.
DR   Gene3D; 3.30.1360.150; -; 1.
DR   Gene3D; 3.40.720.10; Alkaline Phosphatase, subunit A; 1.
DR   InterPro; IPR017850; Alkaline_phosphatase_core_sf.
DR   InterPro; IPR026263; Alkaline_phosphatase_prok.
DR   InterPro; IPR002591; Phosphodiest/P_Trfase.
DR   PANTHER; PTHR10151:SF120; BIS(5'-ADENOSYL)-TRIPHOSPHATASE; 1.
DR   PANTHER; PTHR10151; ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE; 1.
DR   Pfam; PF01663; Phosphodiest; 1.
DR   PIRSF; PIRSF031924; Pi-irrepressible_AP; 1.
DR   SUPFAM; SSF53649; Alkaline phosphatase-like; 1.
PE   4: Predicted;
KW   Phosphoprotein {ECO:0000256|PIRSR:PIRSR031924-50};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           20..570
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012600719"
FT   ACT_SITE        79
FT                   /note="Phosphothreonine intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR031924-50"
FT   BINDING         100
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR031924-51"
FT   BINDING         161..163
FT                   /ligand="substrate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR031924-51"
SQ   SEQUENCE   570 AA;  63328 MW;  F288578A9161C046 CRC64;
     MKKRLSLLLA ATLALPAFAQ KSNKPLDRPK LVVGIVVDQM RYDYLYRFWS KYGNGGFRRL
     LGEGFSYENA HYNYVPTYTG PGHASIYTGT TPSVHGIVGN NWLVREEGKG TYVTEDKTVQ
     AVGGTAVAGQ QSPRHMLTST ITDELRLATN FQSKVIGVCI KDRGSILPAG HAANAAYWYD
     GSNGAFISST FYQATLPTWV QQFNQKQLAA QYLSKAWETL LPIAQYTESS PDDVAWEGAF
     KEEAKPVFPH DLPTLSAAPI TPVKQNMQTE GEKTPVATPR NLDLIRSTPF GNSLTLDFAL
     EALKAEQLGL RGQTDFLALS FSSTDYVGHQ FGPNAIETED TYLRLDRDLE RLFAYLDKVV
     GKKQVLVFLS ADHGAAHSPD FLRDKRIPGG SVGPGLMRDS LQRKLVSLHG PGQWVLSYEN
     QQVYLNRPLI EQKKLDLYQM QREVATLMTG FAGVTRAITA EDLQKSHWES GMLMYLENGY
     FPKRSGDVMV VLEPGWLESY QYPINKGTTH GSSGNYDTHV PIVFWGWHVK HGESSAPTKI
     TDIAPTLAQW LHIQEPDGST GTPLQEVLSR
//