ID   A0A212UHD6_9BACT        Unreviewed;       945 AA.
AC   A0A212UHD6;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE   AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN   ORFNames=SAMN06265337_4068 {ECO:0000313|EMBL:SNC77484.1};
OS   Hymenobacter gelipurpurascens.
OC   Bacteria; Bacteroidota; Cytophagia; Cytophagales; Hymenobacteraceae;
OC   Hymenobacter.
OX   NCBI_TaxID=89968 {ECO:0000313|EMBL:SNC77484.1, ECO:0000313|Proteomes:UP000198131};
RN   [1] {ECO:0000313|EMBL:SNC77484.1, ECO:0000313|Proteomes:UP000198131}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 11116 {ECO:0000313|EMBL:SNC77484.1,
RC   ECO:0000313|Proteomes:UP000198131};
RA   Kim H.J., Triplett B.A.;
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC       {ECO:0000256|ARBA:ARBA00038000}.
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DR   EMBL; FYEW01000003; SNC77484.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A212UHD6; -.
DR   OrthoDB; 9809851at2; -.
DR   Proteomes; UP000198131; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR   GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR   Gene3D; 3.30.190.20; -; 1.
DR   Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR   Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 3.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 3.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR004602; UvrA.
DR   InterPro; IPR041552; UvrA_DNA-bd.
DR   InterPro; IPR041102; UvrA_inter.
DR   NCBIfam; TIGR00630; uvra; 1.
DR   PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR   PANTHER; PTHR43152:SF4; UVRABC SYSTEM PROTEIN A; 1.
DR   Pfam; PF17755; UvrA_DNA-bind; 1.
DR   Pfam; PF17760; UvrA_inter; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW   Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW   DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW   DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW   DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT   DOMAIN          261..595
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000259|PROSITE:PS50893"
FT   DOMAIN          603..941
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000259|PROSITE:PS50893"
SQ   SEQUENCE   945 AA;  105156 MW;  FB8B0FB56CB6F11B CRC64;
     MADNSVLQVA APAADPIDQL DPREFILIKN ARVHNLKNLS VALPRNKFIV VTGLSGSGKS
     SLAFDTLYAE GQRMYVESLS SYARQFLGRM DKPDVDYIRG ISPAIAIEQK VSIKNNRSTV
     GTSTEIYDYL KLLFARVGRT YSPLSGKQVR KDNVADVVDY LMHLPEGTRV MLLSPLLPAE
     DGRPMSKELD LLLQKGYSRV VVNGETAFIE ELIAEGQPEV KGDVHIMIDR AAIQPGDEDL
     TFRLADSVQT AFFEGHGTCL VKLDDETRIF SDRFELDGEV FEEPSVNFFS FNNPYGACQT
     CEGFGSVLGI DEDLVIPDKS LTVYEGAIAP WRTDKQSEWL KPLLKNGIRF DFPIHRPYNE
     LSEAERQLLW KGNKHFDGLD DYFKWVATQT HKIQYRVLQS RYRGRTTCPD CRGTRLRKDA
     QYVKIQDHSI TDLVLLPVSR ALEFFQNLDL PEHEAKVAER LVTEVTNRLE YLNRVGLGYL
     TLNRLSSTLS GGESQRISLA TSLGSALVGS MYILDEPSIG LHPKDAEQLI GVLRSLQQLG
     NTVIVVEHEE KIMEEADQII DIGPEAGSGG GILQFQGTYE EILKDTKSYT GRYLSGKLEV
     AVPKTRRPWR NALELTGARE NNLKNVSVKF PLNVMTVVTG VSGSGKSTLI RRILAPALLK
     QLGGGAGEAT GKFDRLTGVN GQVTHVEFVD QNPIGKSSRS NPVTYVKAYD AIRSLFADQQ
     LAKARGFKPS HFSFNIDGGR CEVCQGEGQV KIEMQFMADI YLTCEACEGR KFKQDILDVK
     FQDKSINEVL EMTIEDSIEF FKGQPKIVER LKPLDDVGLG YIRLGQSANT LSGGEAQRVK
     LASFLTKGNT LQNDKILFIF DEPSTGLHFH DINKLMTALN ALVEQGNSVL IIEHNMDIIK
     CADWVIDLGP EGGINGGHLL FEGTPEDMVK IKDTNHTARF LAEKL
//