ID A0A218P531_9EURY Unreviewed; 201 AA.
AC A0A218P531;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Cation:proton antiporter {ECO:0000313|EMBL:ASJ05896.1};
GN ORFNames=A3L08_00365 {ECO:0000313|EMBL:ASJ05896.1};
OS Thermococcus pacificus.
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Thermococcus.
OX NCBI_TaxID=71998 {ECO:0000313|EMBL:ASJ05896.1, ECO:0000313|Proteomes:UP000197418};
RN [1] {ECO:0000313|EMBL:ASJ05896.1, ECO:0000313|Proteomes:UP000197418}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P-4 {ECO:0000313|EMBL:ASJ05896.1,
RC ECO:0000313|Proteomes:UP000197418};
RA Oger P.M.;
RT "Complete genome sequence of Thermococcus pacificus type strain P4.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; CP015102; ASJ05896.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A218P531; -.
DR KEGG; tpaf:A3L08_00365; -.
DR OrthoDB; 85180at2157; -.
DR Proteomes; UP000197418; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008324; F:monoatomic cation transmembrane transporter activity; IEA:InterPro.
DR InterPro; IPR002758; Cation_antiport_E.
DR PANTHER; PTHR34584; NA(+)/H(+) ANTIPORTER SUBUNIT E1; 1.
DR PANTHER; PTHR34584:SF1; NA(+)_H(+) ANTIPORTER SUBUNIT E1; 1.
DR Pfam; PF01899; MNHE; 1.
DR PIRSF; PIRSF019239; MrpE; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 35..53
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 59..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 90..110
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 201 AA; 23036 MW; 2031D12625B686AE CRC64;
MSRVPFYLKE RLERLRERVT HGQFEASKLP AWERIILTWA VLIAFWVVIS GSLSLDNLLV
GAAVTGIIAA FMRDLLTEDI RKSGHIAEKL LYFTFIYLPQ YVVIMAFRLL ESNLKVAKNV
IFMDINPGIV KIKTDLHSDT GITILANSIT LTPGTLTLDV NKKLGETYLY VHWIDVETLN
REKAGEKIKG DIEEWLKKVF W
//
