ID A0A218P6Z8_9EURY Unreviewed; 600 AA.
AC A0A218P6Z8;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=NADH dehydrogenase {ECO:0000313|EMBL:ASJ06547.1};
GN ORFNames=A3L08_03995 {ECO:0000313|EMBL:ASJ06547.1};
OS Thermococcus pacificus.
OC Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae;
OC Thermococcus.
OX NCBI_TaxID=71998 {ECO:0000313|EMBL:ASJ06547.1, ECO:0000313|Proteomes:UP000197418};
RN [1] {ECO:0000313|EMBL:ASJ06547.1, ECO:0000313|Proteomes:UP000197418}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P-4 {ECO:0000313|EMBL:ASJ06547.1,
RC ECO:0000313|Proteomes:UP000197418};
RA Oger P.M.;
RT "Complete genome sequence of Thermococcus pacificus type strain P4.";
RL Submitted (APR-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the complex I 51 kDa subunit family.
CC {ECO:0000256|ARBA:ARBA00007523}.
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DR EMBL; CP015102; ASJ06547.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A218P6Z8; -.
DR KEGG; tpaf:A3L08_03995; -.
DR OrthoDB; 297477at2157; -.
DR Proteomes; UP000197418; Chromosome.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:UniProt.
DR CDD; cd02980; TRX_Fd_family; 1.
DR Gene3D; 3.10.20.600; -; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 6.10.250.1450; -; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR Gene3D; 3.40.50.11540; NADH-ubiquinone oxidoreductase 51kDa subunit; 1.
DR Gene3D; 1.20.1440.230; NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR011538; Nuo51_FMN-bd.
DR InterPro; IPR037225; Nuo51_FMN-bd_sf.
DR InterPro; IPR019575; Nuop51_4Fe4S-bd.
DR InterPro; IPR037207; Nuop51_4Fe4S-bd_sf.
DR InterPro; IPR019554; Soluble_ligand-bd.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR43578; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR PANTHER; PTHR43578:SF3; NADH-QUINONE OXIDOREDUCTASE SUBUNIT F; 1.
DR Pfam; PF01512; Complex1_51K; 1.
DR Pfam; PF13187; Fer4_9; 1.
DR Pfam; PF10589; NADH_4Fe-4S; 1.
DR Pfam; PF10531; SLBB; 1.
DR SMART; SM00928; NADH_4Fe-4S; 1.
DR SUPFAM; SSF54862; 4Fe-4S ferredoxins; 1.
DR SUPFAM; SSF142019; Nqo1 FMN-binding domain-like; 1.
DR SUPFAM; SSF142984; Nqo1 middle domain-like; 1.
DR SUPFAM; SSF140490; Nqo1C-terminal domain-like; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW FMN {ECO:0000256|ARBA:ARBA00022643}; Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW NAD {ECO:0000256|ARBA:ARBA00023027};
KW Translocase {ECO:0000256|ARBA:ARBA00022967}.
FT DOMAIN 538..567
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 568..597
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
SQ SEQUENCE 600 AA; 66029 MW; 0199F6F461B234AD CRC64;
MSEIKAIAVG MNSCGIAAGA KETYEALKRE LEERGLDVKL KIVGCVGMCY REPLVDIITD
DEIITYGHVD PKKVPRIIEE HVINGKPIKE WIVKRDWWEN GERKTWDVDG YFAKQKKIVL
ENSGYIDPEN IDEYIAAGGY EALKKALQME PEEIIDVIIK SGLRGRGGAG FPTGMKWKFT
RQAPGDEKYI VCNADEGDPG AFMDRNVLEG DPHRVIEGMI IGAYAIGATK GFIYVRAEYP
LAIRRLKIAL KQARERGFLG ENILGSGFSF DIAIKEGAGA FVCGEETALI ASIEGKRGMP
RPRPPYPAQK GLWGKPTNIN NVETWANVPW IIKHGWQAYA SLGTEKSKGT KVFALSGKIK
HGGNVEVPMG ITLREILYEI GGGTKTGKRI KAVQLGGPSG GCIPEELFDT PVDYESVNAT
GAIMGSGGMV VMDEDTCMVD VAKFFLDFTV KESCGKCTFC RLGTKRMWEI LDKFTRGEAT
LEDLEKLEKL AYQVKAGSLC GLGQTAPNPV LTTLRYFRDE YLAHIEGKCP AKVCKPLIRY
VIIADKCTGC TACAIFCPAK VISGERLKPH SIDQEACIKC GTCYEVCRFN AIEILTGRDE
//
