ID A0A218U8N0_9PASE Unreviewed; 760 AA.
AC A0A218U8N0;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=NACHT, LRR and PYD domains-containing protein 3 {ECO:0000313|EMBL:OWK50053.1};
DE Flags: Fragment;
GN Name=NLRP3 {ECO:0000313|EMBL:OWK50053.1};
GN ORFNames=RLOC_00002032 {ECO:0000313|EMBL:OWK50053.1};
OS Lonchura striata domestica (Bengalese finch).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Lonchura.
OX NCBI_TaxID=299123 {ECO:0000313|EMBL:OWK50053.1, ECO:0000313|Proteomes:UP000197619};
RN [1] {ECO:0000313|EMBL:OWK50053.1, ECO:0000313|Proteomes:UP000197619}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=White83orange57 {ECO:0000313|EMBL:OWK50053.1};
RA Colquitt B.M., Brainard M.S.;
RT "Genome of assembly of the Bengalese finch, Lonchura striata domestica.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the NLRP family.
CC {ECO:0000256|ARBA:ARBA00008665}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWK50053.1}.
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DR EMBL; MUZQ01000628; OWK50053.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A218U8N0; -.
DR STRING; 299123.ENSLSDP00000015762; -.
DR Proteomes; UP000197619; Unassembled WGS sequence.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 1.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR007111; NACHT_NTPase.
DR InterPro; IPR041267; NLRP_HD2.
DR InterPro; IPR041075; NOD2_WH.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR45690; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 12; 1.
DR PANTHER; PTHR45690:SF15; NACHT, LRR AND PYD DOMAINS-CONTAINING PROTEIN 14; 1.
DR Pfam; PF13516; LRR_6; 1.
DR Pfam; PF05729; NACHT; 1.
DR Pfam; PF17776; NLRC4_HD2; 1.
DR Pfam; PF17779; NOD2_WH; 1.
DR SMART; SM00368; LRR_RI; 6.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS50837; NACHT; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000197619}.
FT DOMAIN 65..268
FT /note="NACHT"
FT /evidence="ECO:0000259|PROSITE:PS50837"
FT NON_TER 760
FT /evidence="ECO:0000313|EMBL:OWK50053.1"
SQ SEQUENCE 760 AA; 84378 MW; 77127D6C32C87EF7 CRC64;
MEIVRESLSF HSRFTPLTII REPWSKHGAK DGAVGTGQGC ASAGSGGAAA TTALFEPGGD
GQTPQVVVLV GAPGMGKTMM VRKVMVEWGE GTLHTQFDFV FCIDCKAIAL PMEASVADLV
SQCCPDMQMA TGKILDDQKK ILFIFDGFEA LGFSLVQPEA ELSSDPREVK PLELTFMSLL
KKTVLPKASL LITMRPTALG SLRQCLKGEY YMEIQGFSAA RRKEYFHRYF ENPSKADVAF
RFVRGNEILY SLCVIPIMSW TICTILEQEL CGKKNLLECS KATTGMTVFY LSQLLKHRGR
DNPQVLQQFL LQLCSLAAEG IWKHKVLFEE KEIKDYGLDQ PGLLPYFLNE RIPRKGEDNG
SVYAFTHLHL QEFFAALFYV LEDDGETVSS SGKLEKDVNK LLESYKSRKD LNVIVQFLFG
LVSQKSMEYM DKTFGCRISP RVREELLEWL QGRHRGLSHP SQALKISEMD TFHFLFEMNE
KSFAQSALGH FTDLDLHDTK LTLYDQMALY FCIQHWAGLG SITLQGCFFH WQDPEAELDA
SVPCSGVSGG GGHPGALVVR RREEMPCPIH LLCRALRHRD SALQVLRLQW CRLSESCCAE
LAALLAENPG LAHLEVADSS LGDSGVRLLC EGLRTPGSRL RILRLRYSRI TSASCEDLAA
VLGTNTCLEE LDLSFSEDLR DTGVELLCEG LQHCACPLQT LRLGSCRLSG ASCPALAARL
LQGPRLTCPG PSDNELGAHG VLQLCQQLRH PACPLRSRGR
//
