ID A0A218U964_9PASE Unreviewed; 151 AA.
AC A0A218U964;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Caveolin {ECO:0000256|RuleBase:RU000680};
GN Name=CAV3 {ECO:0000313|EMBL:OWK50284.1};
GN ORFNames=RLOC_00013504 {ECO:0000313|EMBL:OWK50284.1};
OS Lonchura striata domestica (Bengalese finch).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Lonchura.
OX NCBI_TaxID=299123 {ECO:0000313|EMBL:OWK50284.1, ECO:0000313|Proteomes:UP000197619};
RN [1] {ECO:0000313|EMBL:OWK50284.1, ECO:0000313|Proteomes:UP000197619}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=White83orange57 {ECO:0000313|EMBL:OWK50284.1};
RA Colquitt B.M., Brainard M.S.;
RT "Genome of assembly of the Bengalese finch, Lonchura striata domestica.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May act as a scaffolding protein within caveolar membranes.
CC Interacts directly with G-protein alpha subunits and can functionally
CC regulate their activity. {ECO:0000256|RuleBase:RU000680}.
CC -!- SUBCELLULAR LOCATION: Cell membrane, sarcolemma
CC {ECO:0000256|ARBA:ARBA00004135}. Cell membrane
CC {ECO:0000256|ARBA:ARBA00004202, ECO:0000256|RuleBase:RU000680};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004202,
CC ECO:0000256|RuleBase:RU000680}. Golgi apparatus membrane
CC {ECO:0000256|RuleBase:RU000680}; Peripheral membrane protein
CC {ECO:0000256|RuleBase:RU000680}. Membrane, caveola
CC {ECO:0000256|RuleBase:RU000680}; Peripheral membrane protein
CC {ECO:0000256|RuleBase:RU000680}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the caveolin family.
CC {ECO:0000256|ARBA:ARBA00010988, ECO:0000256|RuleBase:RU000680}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWK50284.1}.
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DR EMBL; MUZQ01000575; OWK50284.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A218U964; -.
DR STRING; 299123.ENSLSDP00000002935; -.
DR OrthoDB; 3740765at2759; -.
DR Proteomes; UP000197619; Unassembled WGS sequence.
DR GO; GO:0005901; C:caveola; IEA:UniProtKB-SubCell.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0042383; C:sarcolemma; IEA:UniProtKB-SubCell.
DR GO; GO:0070836; P:caveola assembly; IEA:InterPro.
DR InterPro; IPR001612; Caveolin.
DR InterPro; IPR018361; Caveolin_CS.
DR PANTHER; PTHR10844; CAVEOLIN; 1.
DR PANTHER; PTHR10844:SF16; CAVEOLIN-3; 1.
DR Pfam; PF01146; Caveolin; 1.
DR PROSITE; PS01210; CAVEOLIN; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|RuleBase:RU000680};
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034,
KW ECO:0000256|RuleBase:RU000680};
KW Membrane {ECO:0000256|RuleBase:RU000680, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000197619};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 75..102
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 151 AA; 17322 MW; ABD5AA9DFD353015 CRC64;
MAEERGELQE RILGKDPLTK EIDLVNRDPR HINEDVVKVD FEDVIAEPVG TYSFDGVWKT
SYTTFTVSKY WCYRLLSAVL GIPLAVIWGF LFALISFCHI WAVVPCIKSY LIEIQCVSRI
YSLCIHTFCD PLFEALAKIC SNVRVAVRKE I
//
