ID A0A218UA21_9PASE Unreviewed; 386 AA.
AC A0A218UA21;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 03-MAY-2023, entry version 16.
DE RecName: Full=Clusterin {ECO:0000256|RuleBase:RU000629};
GN Name=CLU {ECO:0000313|EMBL:OWK50525.1};
GN ORFNames=RLOC_00006493 {ECO:0000313|EMBL:OWK50525.1};
OS Lonchura striata domestica (Bengalese finch).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Lonchura.
OX NCBI_TaxID=299123 {ECO:0000313|EMBL:OWK50525.1, ECO:0000313|Proteomes:UP000197619};
RN [1] {ECO:0000313|EMBL:OWK50525.1, ECO:0000313|Proteomes:UP000197619}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=White83orange57 {ECO:0000313|EMBL:OWK50525.1};
RA Colquitt B.M., Brainard M.S.;
RT "Genome of assembly of the Bengalese finch, Lonchura striata domestica.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the clusterin family.
CC {ECO:0000256|ARBA:ARBA00010069, ECO:0000256|RuleBase:RU000629}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWK50525.1}.
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DR EMBL; MUZQ01000531; OWK50525.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A218UA21; -.
DR STRING; 299123.ENSLSDP00000014279; -.
DR OrthoDB; 4321242at2759; -.
DR Proteomes; UP000197619; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR InterPro; IPR000753; Clusterin-like.
DR InterPro; IPR016015; Clusterin_C.
DR InterPro; IPR016014; Clusterin_N.
DR PANTHER; PTHR10970; CLUSTERIN; 1.
DR PANTHER; PTHR10970:SF1; CLUSTERIN; 1.
DR Pfam; PF01093; Clusterin; 1.
DR SMART; SM00035; CLa; 1.
DR SMART; SM00030; CLb; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Reference proteome {ECO:0000313|Proteomes:UP000197619};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 1..186
FT /note="Clusterin N-terminal"
FT /evidence="ECO:0000259|SMART:SM00030"
FT DOMAIN 172..381
FT /note="Clusterin C-terminal"
FT /evidence="ECO:0000259|SMART:SM00035"
FT COILED 15..42
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 386 AA; 44831 MW; C034C706E419F768 CRC64;
MRRMQALLQR SDRGHRELQR SLQQAQRGKE EAVQLALQKE QELSARGERC NASAQELWER
CKPCLRQRCM RLYSRTCRSG AGLVGRQLEQ FLNQSSPVSV WLDEERLERL RERDERQERR
RQELEERFGL LEDGVQDLFQ DSSRLQAHLH PLVQPPFGAG RFPRRFRRFS GAFQPLFQAP
HGGFQQLFQP LFQLLEDSQR SWESPWAELG TESRNFSNDK MVCREIRRNS AGCLRMRDEC
EQCREILALD CGQEDPSQQE LREQLEDAVR VAERFARRYD SLLREFQEEM FNTSGLLDQL
SRRFGWVARL ANRSLGSDGV LQVTAVLSKA ADPADPAAPD TEVTVQLFDS EPLALTVPGH
IPWDDPKFME VVAEQALQRF KENAVE
//
