ID A0A218UCP1_9PASE Unreviewed; 642 AA.
AC A0A218UCP1;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=Hepatoma-derived growth factor-related protein 2 {ECO:0000256|ARBA:ARBA00039350};
GN Name=HDGFRP2 {ECO:0000313|EMBL:OWK51479.1};
GN ORFNames=RLOC_00005045 {ECO:0000313|EMBL:OWK51479.1};
OS Lonchura striata domestica (Bengalese finch).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Lonchura.
OX NCBI_TaxID=299123 {ECO:0000313|EMBL:OWK51479.1, ECO:0000313|Proteomes:UP000197619};
RN [1] {ECO:0000313|EMBL:OWK51479.1, ECO:0000313|Proteomes:UP000197619}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=White83orange57 {ECO:0000313|EMBL:OWK51479.1};
RA Colquitt B.M., Brainard M.S.;
RT "Genome of assembly of the Bengalese finch, Lonchura striata domestica.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the HDGF family.
CC {ECO:0000256|ARBA:ARBA00005309}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWK51479.1}.
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DR EMBL; MUZQ01000430; OWK51479.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A218UCP1; -.
DR STRING; 299123.ENSLSDP00000001953; -.
DR OrthoDB; 4271850at2759; -.
DR Proteomes; UP000197619; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.
DR CDD; cd20149; PWWP_HDGFL2; 1.
DR Gene3D; 2.30.30.140; -; 1.
DR Gene3D; 1.20.930.10; Conserved domain common to transcription factors TFIIS, elongin A, CRSP70; 1.
DR InterPro; IPR036218; HIVI-bd_sf.
DR InterPro; IPR021567; LEDGF_IBD.
DR InterPro; IPR000313; PWWP_dom.
DR InterPro; IPR035441; TFIIS/LEDGF_dom_sf.
DR PANTHER; PTHR12550; HEPATOMA-DERIVED GROWTH FACTOR-RELATED; 1.
DR PANTHER; PTHR12550:SF18; HEPATOMA-DERIVED GROWTH FACTOR-RELATED PROTEIN 2; 1.
DR Pfam; PF11467; LEDGF; 1.
DR Pfam; PF00855; PWWP; 1.
DR SMART; SM00293; PWWP; 1.
DR SUPFAM; SSF140576; HIV integrase-binding domain; 1.
DR SUPFAM; SSF63748; Tudor/PWWP/MBT; 1.
DR PROSITE; PS50812; PWWP; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Myogenesis {ECO:0000256|ARBA:ARBA00022541};
KW Reference proteome {ECO:0000313|Proteomes:UP000197619}.
FT DOMAIN 7..64
FT /note="PWWP"
FT /evidence="ECO:0000259|PROSITE:PS50812"
FT REGION 87..448
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 523..642
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 87..107
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 125..151
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 184..207
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 217..233
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 247..284
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 293..448
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 536..570
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 642 AA; 71969 MW; F3987DCE02E0BFF9 CRC64;
MPHSFKPGDL VFAKMKGYPH WPARIDDIAD GAVKPPPNKY PIFFFGTHET AFLGPKDLFP
YEKYKDKYGK PNKRKGFNEG LWEIQNNPHA SYSAPAPASS SDSDVPENDP MAGSDAGDDE
DDSAMATVPT EKVDSEEDSD RGSDHSGLKR KSLAMKMPVT KRPRKSSSDL DQGSPSVTEE
ENSETSSESE KNSDQDFTPE KKPVARAPRR MPAAGRKKKK VESGSDSDSK VDSDLEMGNA
TVDMTKSDSD SDSDVSVKKA PRGRKPAEKP PPKPRGRKPK PERVPSSSSS DSDSDSDVDR
ISEWKRRDEE RRRELEEKRK REQEEEIRRL REQEKEEKEK RKEKAEKSEE VHSDSDSSAE
DEMAKKGRRG RAKAPSSSDS ELEQEKEVKK PAKKQPSELS RKPNQKEKRG RAEEKPRNKP
LKVERGRKKS DPIPERRMEK KKEPTVEEKL QKLHSEIKFA LKVDNPDIKR CLSALEELGT
LQVTSHILQK HTDVVATLKK IRRYKANKDV MEKAAEVYTR LKSRVLGPKM ESIQKANKAG
PEKDKGEAEK GQEKLSGAET RNEKGEEETN ADLSGPVNGE SLSQKSEGTE EKEKSQGPGA
GELEASTEEP HNNSVQDYPK AGLERARGES EAADEEEEEE ES
//
