ID A0A218UF49_9PASE Unreviewed; 462 AA.
AC A0A218UF49;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 10.
DE RecName: Full=Zona pellucida-like domain-containing protein 1 {ECO:0000256|ARBA:ARBA00040851};
DE AltName: Full=Cupulin {ECO:0000256|ARBA:ARBA00043069};
GN Name=ZPLD1 {ECO:0000313|EMBL:OWK52208.1};
GN ORFNames=RLOC_00007392 {ECO:0000313|EMBL:OWK52208.1};
OS Lonchura striata domestica (Bengalese finch).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Lonchura.
OX NCBI_TaxID=299123 {ECO:0000313|EMBL:OWK52208.1, ECO:0000313|Proteomes:UP000197619};
RN [1] {ECO:0000313|EMBL:OWK52208.1, ECO:0000313|Proteomes:UP000197619}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=White83orange57 {ECO:0000313|EMBL:OWK52208.1};
RA Colquitt B.M., Brainard M.S.;
RT "Genome of assembly of the Bengalese finch, Lonchura striata domestica.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Glycoprotein which is a component of the gelatinous
CC extracellular matrix in the cupulae of the vestibular organ.
CC {ECO:0000256|ARBA:ARBA00037652}.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle membrane
CC {ECO:0000256|ARBA:ARBA00004358}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004358}. Secreted, extracellular space,
CC extracellular matrix {ECO:0000256|ARBA:ARBA00004498}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWK52208.1}.
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DR EMBL; MUZQ01000365; OWK52208.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A218UF49; -.
DR STRING; 299123.ENSLSDP00000006965; -.
DR Proteomes; UP000197619; Unassembled WGS sequence.
DR GO; GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.
DR Gene3D; 2.60.40.4100; Zona pellucida, ZP-C domain; 2.
DR InterPro; IPR042235; ZP-C.
DR InterPro; IPR001507; ZP_dom.
DR PANTHER; PTHR14002; ENDOGLIN/TGF-BETA RECEPTOR TYPE III; 1.
DR PANTHER; PTHR14002:SF24; ZONA PELLUCIDA-LIKE DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00100; Zona_pellucida; 2.
DR SMART; SM00241; ZP; 1.
DR PROSITE; PS51034; ZP_2; 1.
PE 4: Predicted;
KW Cytoplasmic vesicle {ECO:0000256|ARBA:ARBA00023329};
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000197619};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..462
FT /note="Zona pellucida-like domain-containing protein 1"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012690947"
FT TRANSMEM 420..443
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 43..376
FT /note="ZP"
FT /evidence="ECO:0000259|PROSITE:PS51034"
SQ SEQUENCE 462 AA; 51110 MW; E00759D7AFAC7F88 CRC64;
MEQVWLLLLL TIKVLPVTAQ FNGYNCDANL HSRFPAERDI NVFCGVQTIT MKINFCTVLF
SGYSETDLAL NGKHGDAHCR GFINNNTFPA VVIFIINLST LESCGNTLVV SSARGINAYG
NTSVVQIGNV SGYIDTPDPP TIISYLPGLL YKFSCSYPLE YLVNNTQLAS SSAAISVREN
NGTFISTLNL LLYNDSTYSQ QLLIPSTGLP LKTKIYAAVR ATNLDGRWNV LMDYCYTTPS
GNPSDDLRYD LFFRSRVSVT TGIKWHFGLA VVLQNKSVFL QESIIFPAKG FKMLTELLIP
VSLFSTKNSC DKDPQTTIIE NGKSQMGRFS FEVFRFVKHK NQKMSTVFLH CVTKLCRADD
CPFLVPVSCN YLGINPGVLL TSVMGVWMAQ NQTDYEMPTN NSQLAHPNGA PFQMNPVTSA
LISGIVVLGI SSIFFFVCSL TLLHRNWPNS SVLSGIQNPV FN
//
