ID   A0A218UJQ6_9PASE        Unreviewed;       828 AA.
AC   A0A218UJQ6;
DT   27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT   27-SEP-2017, sequence version 1.
DT   22-FEB-2023, entry version 15.
DE   SubName: Full=DEP domain-containing protein 1A {ECO:0000313|EMBL:OWK53886.1};
GN   Name=DEPDC1 {ECO:0000313|EMBL:OWK53886.1};
GN   ORFNames=RLOC_00003933 {ECO:0000313|EMBL:OWK53886.1};
OS   Lonchura striata domestica (Bengalese finch).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC   Estrildinae; Lonchura.
OX   NCBI_TaxID=299123 {ECO:0000313|EMBL:OWK53886.1, ECO:0000313|Proteomes:UP000197619};
RN   [1] {ECO:0000313|EMBL:OWK53886.1, ECO:0000313|Proteomes:UP000197619}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=White83orange57 {ECO:0000313|EMBL:OWK53886.1};
RA   Colquitt B.M., Brainard M.S.;
RT   "Genome of assembly of the Bengalese finch, Lonchura striata domestica.";
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OWK53886.1}.
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DR   EMBL; MUZQ01000260; OWK53886.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A218UJQ6; -.
DR   Proteomes; UP000197619; Unassembled WGS sequence.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd04405; RhoGAP_BRCC3-like; 1.
DR   Gene3D; 1.10.555.10; Rho GTPase activation protein; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR000591; DEP_dom.
DR   InterPro; IPR008936; Rho_GTPase_activation_prot.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR16206; DEP DOMAIN-CONTAINING; 1.
DR   PANTHER; PTHR16206:SF12; DEP DOMAIN-CONTAINING PROTEIN 1A; 1.
DR   Pfam; PF00610; DEP; 1.
DR   SMART; SM00049; DEP; 1.
DR   SUPFAM; SSF48350; GTPase activation domain, GAP; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000197619}.
FT   DOMAIN          1..81
FT                   /note="DEP"
FT                   /evidence="ECO:0000259|SMART:SM00049"
FT   REGION          96..115
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          323..342
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          360..392
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          465..491
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        360..381
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   828 AA;  92819 MW;  85EE135147A59884 CRC64;
     MPLRRHRQRL RSHGGCFTAA EAADWLHPVL RSSSGFGPDV TRQQTVQLLR KFLKNHVIED
     IKGRWGAENL EDNGDLYRSI RNAFNISSIH YRFPPTSPVK PLPSPPRESL ENFSGDKGKL
     FKLPSSSKRG LKKQEFLQSV VITSVPHSIA VGLHLSTTRF QENIARPKAD VTGEKKESTV
     PRREISQEYV QETWRNIIQI HLQTILGLPS LEEVLQPAQI TPEFVMYNMS NTSKHGVVIL
     QDKAEDLPHW VLSAMKCLAY WPRNNDMSQA TYSGFERDVF RTVADYFLSL PEPLLTFEYY
     ELFVNILVLC GCIQIPDLGS GNRSVQEEKC DPQPSKPPHL NSFKSTECLL LSLLLKGSDK
     KEKGEASRRF SSEELRAQNQ HRKKRQQGSA GNLIGGSCQN LAASRNDQEP PGAFRTRCYS
     LERIGAAAAS SVCGKGGGVS TSRRSRELLE EHGVTSVLGL GWDSSGPAQG LRGGPGPCPW
     AEEPRGGSRG SLSLLGRRSC RSCSAINRPR AEITVQPLPR GQGTPSPSVA ISVQRRLCRS
     STDLSGRSAP PSPCVLAGTN LLQPHLERIA VEALQICCLL LPPPRRRKLQ LLLRMVARIS
     GNVDMPRLHD AMGNRSLVRA GKALLKRMQM IPQPDFPASC YLKSQTGLGG TLKPSSLQFN
     ALIQTFSRCV LRCAEEEDLD ELLSTRLLSF LMDHQQEIFQ VPVYLQVAVQ DHLKYMEKAQ
     CKQEKEEICA ILPTYSYCKQ ITPQEFEEQK VSTSQAAVAE LLENIIQDKN LSVKDKKKKL
     KQFQREYPQI YGSRFPRTES EAQLLENKPT LKQPLLSLRK PKFRSLRY
//