ID A0A218UK59_9PASE Unreviewed; 427 AA.
AC A0A218UK59;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 22-FEB-2023, entry version 12.
DE SubName: Full=Vasopressin V1b receptor {ECO:0000313|EMBL:OWK54046.1};
GN Name=AVPR1B {ECO:0000313|EMBL:OWK54046.1};
GN ORFNames=RLOC_00004397 {ECO:0000313|EMBL:OWK54046.1};
OS Lonchura striata domestica (Bengalese finch).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Lonchura.
OX NCBI_TaxID=299123 {ECO:0000313|EMBL:OWK54046.1, ECO:0000313|Proteomes:UP000197619};
RN [1] {ECO:0000313|EMBL:OWK54046.1, ECO:0000313|Proteomes:UP000197619}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=White83orange57 {ECO:0000313|EMBL:OWK54046.1};
RA Colquitt B.M., Brainard M.S.;
RT "Genome of assembly of the Bengalese finch, Lonchura striata domestica.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651,
CC ECO:0000256|RuleBase:RU046427}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004651, ECO:0000256|RuleBase:RU046427}.
CC Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC Vasopressin/oxytocin receptor subfamily.
CC {ECO:0000256|RuleBase:RU046427}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWK54046.1}.
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DR EMBL; MUZQ01000252; OWK54046.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A218UK59; -.
DR STRING; 299123.ENSLSDP00000002484; -.
DR Proteomes; UP000197619; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005000; F:vasopressin receptor activity; IEA:InterPro.
DR CDD; cd15386; 7tmA_V1bR; 1.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR InterPro; IPR001817; Vasoprsn_rcpt.
DR InterPro; IPR000628; Vprs_rcpt_V1B.
DR PANTHER; PTHR24241; NEUROPEPTIDE RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR; 1.
DR PANTHER; PTHR24241:SF18; VASOPRESSIN V1B RECEPTOR; 1.
DR Pfam; PF00001; 7tm_1; 1.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR PRINTS; PR00896; VASOPRESSINR.
DR PRINTS; PR00897; VASOPRSNV1BR.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW G-protein coupled receptor {ECO:0000256|RuleBase:RU046427};
KW Glycoprotein {ECO:0000256|RuleBase:RU046427};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU046427};
KW Receptor {ECO:0000256|RuleBase:RU046427, ECO:0000313|EMBL:OWK54046.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000197619};
KW Transducer {ECO:0000256|RuleBase:RU046427};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU046427};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU046427}.
FT TRANSMEM 45..66
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU046427"
FT TRANSMEM 78..96
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU046427"
FT TRANSMEM 116..137
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU046427"
FT TRANSMEM 158..181
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU046427"
FT TRANSMEM 206..229
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU046427"
FT TRANSMEM 281..303
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU046427"
FT TRANSMEM 315..338
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU046427"
FT DOMAIN 58..335
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 380..399
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 427 AA; 47032 MW; 3308015F252A8278 CRC64;
MEPGWGWNSS HQSPPGHGQG LLRLAGDPNL TVLHTRDEEL AKAEVGVLGT ILAVATVGNL
GVLLAMYRLR RKMSRMHLFI LHLGLSDLGV ALFQVLPQLL WKVTYRFLGP DPLCRAVKYL
QVLSMYASTY MLMVMTLDRY LAVCRPLQSL QQPSRQAYAM IGATWLLSCL LSLPQVFIFS
LREVRPGSGV LDCWADFGYP WGARAYITWT TLCVFVLPVG VLSVCYSLIC HEICKNLKGK
TQSGAPGSGG AAAAAGPGQP SRVSSVRTIS RAKIRTVKMT FVIVAAYVTC WAPFFSVQMW
SVWDQDAPDD ESSNVAFSIT MLLASLSSCC NPWIYLFFSG HLLQDAGHCQ GCWGRPRAGL
HRANSTGSLC SRKTTVLSHS HQGHQEHQGH QEHREHREHQ AGLPLHGDSV RELYPPCDEG
VTEAGML
//
