ID   A0A218UNI4_9PASE        Unreviewed;       754 AA.
AC   A0A218UNI4;
DT   27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT   27-SEP-2017, sequence version 1.
DT   13-SEP-2023, entry version 19.
DE   SubName: Full=Protocadherin alpha-C1 {ECO:0000313|EMBL:OWK55226.1};
GN   Name=PCDHAC1 {ECO:0000313|EMBL:OWK55226.1};
GN   ORFNames=RLOC_00004995 {ECO:0000313|EMBL:OWK55226.1};
OS   Lonchura striata domestica (Bengalese finch).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC   Estrildinae; Lonchura.
OX   NCBI_TaxID=299123 {ECO:0000313|EMBL:OWK55226.1, ECO:0000313|Proteomes:UP000197619};
RN   [1] {ECO:0000313|EMBL:OWK55226.1, ECO:0000313|Proteomes:UP000197619}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=White83orange57 {ECO:0000313|EMBL:OWK55226.1};
RA   Colquitt B.M., Brainard M.S.;
RT   "Genome of assembly of the Bengalese finch, Lonchura striata domestica.";
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OWK55226.1}.
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DR   EMBL; MUZQ01000211; OWK55226.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A218UNI4; -.
DR   Proteomes; UP000197619; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR   GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR   CDD; cd11304; Cadherin_repeat; 5.
DR   Gene3D; 2.60.40.60; Cadherins; 6.
DR   InterPro; IPR002126; Cadherin-like_dom.
DR   InterPro; IPR015919; Cadherin-like_sf.
DR   InterPro; IPR020894; Cadherin_CS.
DR   InterPro; IPR013164; Cadherin_N.
DR   PANTHER; PTHR24028; CADHERIN-87A; 1.
DR   PANTHER; PTHR24028:SF153; PROTOCADHERIN ALPHA-C1; 1.
DR   Pfam; PF00028; Cadherin; 5.
DR   Pfam; PF08266; Cadherin_2; 1.
DR   PRINTS; PR00205; CADHERIN.
DR   SMART; SM00112; CA; 5.
DR   SUPFAM; SSF49313; Cadherin-like; 5.
DR   PROSITE; PS00232; CADHERIN_1; 3.
DR   PROSITE; PS50268; CADHERIN_2; 5.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW   ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000197619};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..754
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012081134"
FT   TRANSMEM        639..662
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          82..190
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          191..297
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          298..402
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          403..512
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
FT   DOMAIN          537..624
FT                   /note="Cadherin"
FT                   /evidence="ECO:0000259|PROSITE:PS50268"
SQ   SEQUENCE   754 AA;  81702 MW;  12C3F52437000107 CRC64;
     MRGYLMVFCL ICCTADGQIV YSIAEETERG ASVGNIAKDL GIDAATLSAR KFRMITGSKN
     PLELYRMEFK VLDINDNSPS FPLSEYHINM PEFLSPGARF TLPSAQDLDE GANSVQNYTL
     SLDEHFYLEM QIRGDGSKYP ELVLKKALDR EQQATHRLLL TAKDGGNPPK SGDVPVIVTV
     LDTNDNAPEF EHSVYRASIL ENSPSGTLVV QVHATDLDEG PNGEVRYSFS NTTSADLQRM
     FSIHPHTGEV TVNGVLAVQR PLLEMLIEAR DNGAFGMSST AKLLVEITDV NNHGPEITIT
     SLSSPIPEDA IPGTVIALLS ILDKDPGENG KVTCQISENL PFQLKPSLQN YYSLVTSELL
     DRELISEYNI TITATDLGSP PLSTQKTVWV QISDVNDNPP VFSAGAFDVF VEENNPLGAF
     LYQVSASDPD IGENGRVSYV LRNSTVAGSA LTSFLSMNLA NGSIYAKRAF DFEQLRSFHF
     QVEAKDNGSP ALSAAITVNV YISDQNDNAP AILYPTSQNG SVAVEVVPRL ADEDYLVTKV
     VADDEDNAQN AWLSYHLAHS SDSTLFQLSP HTGELRTTRS MRSTDFLKHK VVVVVRDHGD
     PPLSSTVTVG ILLADTLPQA LPDFDDSGEP PPLLNTTNIY LIVSLSCVSF IFAAFIFFLA
     IIRLCRCRTC CCSGCCCPAE DYQKASVGLG PSNSSIPNGD AGNVPSGSRL QVPGPCIQVQ
     QVQSDRLSAV LVHGISEKLS TLLCCAGDKG TSDY
//