ID   A0A218UPQ2_9PASE        Unreviewed;       498 AA.
AC   A0A218UPQ2;
DT   27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT   27-SEP-2017, sequence version 1.
DT   24-JAN-2024, entry version 21.
DE   SubName: Full=NGFI-A-binding protein 1 {ECO:0000313|EMBL:OWK55342.1};
GN   Name=NAB1 {ECO:0000313|EMBL:OWK55342.1};
GN   ORFNames=RLOC_00006345 {ECO:0000313|EMBL:OWK55342.1};
OS   Lonchura striata domestica (Bengalese finch).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC   Estrildinae; Lonchura.
OX   NCBI_TaxID=299123 {ECO:0000313|EMBL:OWK55342.1, ECO:0000313|Proteomes:UP000197619};
RN   [1] {ECO:0000313|EMBL:OWK55342.1, ECO:0000313|Proteomes:UP000197619}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=White83orange57 {ECO:0000313|EMBL:OWK55342.1};
RA   Colquitt B.M., Brainard M.S.;
RT   "Genome of assembly of the Bengalese finch, Lonchura striata domestica.";
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Homomultimers may associate with EGR1 bound to DNA.
CC       {ECO:0000256|ARBA:ARBA00011364}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the NAB family. {ECO:0000256|ARBA:ARBA00008864}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OWK55342.1}.
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DR   EMBL; MUZQ01000206; OWK55342.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A218UPQ2; -.
DR   STRING; 299123.ENSLSDP00000010793; -.
DR   OrthoDB; 4181992at2759; -.
DR   Proteomes; UP000197619; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003712; F:transcription coregulator activity; IEA:InterPro.
DR   GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 1.20.120.2010; NAB conserved domain 2; 1.
DR   InterPro; IPR006986; Nab1_C.
DR   InterPro; IPR006989; NAB_co-repressor_dom.
DR   InterPro; IPR039040; NAB_fam.
DR   InterPro; IPR006988; Nab_N.
DR   InterPro; IPR038398; NCD2_sf.
DR   PANTHER; PTHR12623; NGFI-A BINDING PROTEIN; 1.
DR   PANTHER; PTHR12623:SF9; NGFI-A-BINDING PROTEIN 1; 1.
DR   Pfam; PF04902; Nab1; 1.
DR   Pfam; PF04904; NCD1; 1.
DR   Pfam; PF04905; NCD2; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000197619};
KW   Repressor {ECO:0000256|ARBA:ARBA00022491};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          6..83
FT                   /note="Nab N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04904"
FT   DOMAIN          190..316
FT                   /note="NAB co-repressor"
FT                   /evidence="ECO:0000259|Pfam:PF04905"
FT   DOMAIN          321..497
FT                   /note="Nab1 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF04902"
FT   REGION          141..188
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          399..425
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        141..186
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        399..413
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   498 AA;  55573 MW;  94DD7E240B979715 CRC64;
     MASALPRTLG ELQLYRILQK ANLLFYFDAF IQQGGDDVQQ LCEAGEEEFL EIMALVGMAS
     KPLHVRRLQK ALRDWVTNPG LFNQPLTSLP VSSIPIYKLP EGSPAWLGIS CSSYERNSST
     REPHLKIPKC AATTCVQSVG TSKSDVGSLS LQGSSEPRLW QGHHTTESEH SLSPADLGSP
     ASPKENSETL DAAAALSVAE CVERMVPSLP KSDSNEVKEL LKTNKKLAKM IGHIFEMSDD
     DPHKEEEIRK YSAIYGRFDS KRKDGKHLTL HELTVNEAAA QLCVKDNALL TRRDELFALA
     RQISREVTYK YTYRTTKSKC GERDELSPKR IKIEDGYPDF QDTVQTLYQQ DKMPLALAKG
     KSEDPTALNS QSEKVMAKQM EFLCNQAALE RRLSTGCYRQ NSEEHSPNGM SLDNADGQGE
     RPLNLRMSNL PSRQMQHISL DGEQHVGKSL CSDLIRLYPS GEAKSQSSEG LGILKDFPHS
     AFNNIERKVI KTEPEDTR
//