ID   A0A218URD7_9PASE        Unreviewed;       180 AA.
AC   A0A218URD7;
DT   27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT   27-SEP-2017, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   RecName: Full=Pro-adrenomedullin {ECO:0000256|ARBA:ARBA00023472};
GN   Name=ADM {ECO:0000313|EMBL:OWK55922.1};
GN   ORFNames=RLOC_00006853 {ECO:0000313|EMBL:OWK55922.1};
OS   Lonchura striata domestica (Bengalese finch).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC   Estrildinae; Lonchura.
OX   NCBI_TaxID=299123 {ECO:0000313|EMBL:OWK55922.1, ECO:0000313|Proteomes:UP000197619};
RN   [1] {ECO:0000313|EMBL:OWK55922.1, ECO:0000313|Proteomes:UP000197619}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=White83orange57 {ECO:0000313|EMBL:OWK55922.1};
RA   Colquitt B.M., Brainard M.S.;
RT   "Genome of assembly of the Bengalese finch, Lonchura striata domestica.";
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC   -!- SIMILARITY: Belongs to the adrenomedullin family.
CC       {ECO:0000256|ARBA:ARBA00010575}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OWK55922.1}.
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DR   EMBL; MUZQ01000182; OWK55922.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A218URD7; -.
DR   STRING; 299123.ENSLSDP00000025719; -.
DR   OrthoDB; 4548241at2759; -.
DR   Proteomes; UP000197619; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:InterPro.
DR   InterPro; IPR021116; Calcitonin/adrenomedullin.
DR   InterPro; IPR001710; Pro-ADM.
DR   PANTHER; PTHR23414; ADRENOMEDULLIN, ADM; 1.
DR   PANTHER; PTHR23414:SF3; PRO-ADRENOMEDULLIN; 1.
DR   Pfam; PF00214; Calc_CGRP_IAPP; 1.
DR   PRINTS; PR00801; ADRENOMEDULN.
PE   3: Inferred from homology;
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157,
KW   ECO:0000256|PIRSR:PIRSR621116-50};
KW   Reference proteome {ECO:0000313|Proteomes:UP000197619};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..21
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           22..180
FT                   /note="Pro-adrenomedullin"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5012148941"
FT   REGION          128..180
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   DISULFID        107..112
FT                   /evidence="ECO:0000256|PIRSR:PIRSR621116-50"
SQ   SEQUENCE   180 AA;  20327 MW;  68C21C5C42CEBB26 CRC64;
     MQLLHVALLY LGSVTFFGVD AARVDVATEF KRKWTKWALS RAKRDVKPAG LLRGLGAAAD
     VLPLIRTQDV KEDSRVSPSS NREDAHIRVK RYRQSINRFP HFQTKACRFG TCTVHWLVDE
     LHRAAVNDRN DAAPPNKISP QGYGRRRRSL PERRSPARSP SSGRRPRTRR AQPLAAVLGV
//