ID A0A218URV7_9PASE Unreviewed; 1043 AA.
AC A0A218URV7;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Cysteine-rich motor neuron 1 protein {ECO:0000313|EMBL:OWK56348.1};
GN Name=CRIM1 {ECO:0000313|EMBL:OWK56348.1};
GN ORFNames=RLOC_00014718 {ECO:0000313|EMBL:OWK56348.1};
OS Lonchura striata domestica (Bengalese finch).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Lonchura.
OX NCBI_TaxID=299123 {ECO:0000313|EMBL:OWK56348.1, ECO:0000313|Proteomes:UP000197619};
RN [1] {ECO:0000313|EMBL:OWK56348.1, ECO:0000313|Proteomes:UP000197619}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=White83orange57 {ECO:0000313|EMBL:OWK56348.1};
RA Colquitt B.M., Brainard M.S.;
RT "Genome of assembly of the Bengalese finch, Lonchura striata domestica.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWK56348.1}.
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DR EMBL; MUZQ01000161; OWK56348.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A218URV7; -.
DR STRING; 299123.ENSLSDP00000019938; -.
DR OrthoDB; 2946817at2759; -.
DR Proteomes; UP000197619; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:InterPro.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR Gene3D; 6.20.200.20; -; 5.
DR Gene3D; 2.10.70.10; Complement Module, domain 1; 1.
DR InterPro; IPR004094; Antistasin-like.
DR InterPro; IPR045813; CRIM1_C.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR011061; Hirudin/antistatin.
DR InterPro; IPR000867; IGFBP-like.
DR InterPro; IPR001007; VWF_dom.
DR PANTHER; PTHR46439; CYSTEINE-RICH MOTOR NEURON 1 PROTEIN; 1.
DR PANTHER; PTHR46439:SF1; CYSTEINE-RICH MOTOR NEURON 1 PROTEIN; 1.
DR Pfam; PF02822; Antistasin; 4.
DR Pfam; PF19442; CRIM1_C; 1.
DR Pfam; PF00219; IGFBP; 1.
DR Pfam; PF00093; VWC; 6.
DR SMART; SM00121; IB; 1.
DR SMART; SM00214; VWC; 6.
DR SMART; SM00215; VWC_out; 3.
DR SUPFAM; SSF57603; FnI-like domain; 6.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR SUPFAM; SSF57262; Leech antihemostatic proteins; 3.
DR PROSITE; PS51252; ANTISTASIN; 4.
DR PROSITE; PS51323; IGFBP_N_2; 1.
DR PROSITE; PS01208; VWFC_1; 4.
DR PROSITE; PS50184; VWFC_2; 6.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000197619};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..41
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 42..1043
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012465518"
FT TRANSMEM 948..968
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 40..119
FT /note="IGFBP N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51323"
FT DOMAIN 341..398
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 408..464
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 476..505
FT /note="Antistasin-like"
FT /evidence="ECO:0000259|PROSITE:PS51252"
FT DOMAIN 512..539
FT /note="Antistasin-like"
FT /evidence="ECO:0000259|PROSITE:PS51252"
FT DOMAIN 546..571
FT /note="Antistasin-like"
FT /evidence="ECO:0000259|PROSITE:PS51252"
FT DOMAIN 574..599
FT /note="Antistasin-like"
FT /evidence="ECO:0000259|PROSITE:PS51252"
FT DOMAIN 613..670
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 684..742
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 758..816
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
FT DOMAIN 824..881
FT /note="VWFC"
FT /evidence="ECO:0000259|PROSITE:PS50184"
SQ SEQUENCE 1043 AA; 114343 MW; 233A7E4910B28735 CRC64;
MYLAAVSAGR RRPGGDGGWH LAAAGWLFLL ALLLGESGTS ALVCLPCDES KCEEPKSCPG
SIVLGICGCC SMCARQRNES CGGVYGLHGA CDRGLRCVIR PPLNGDSITE YEVGVCEDEN
WDDDQLLGFE PCNENLITGC NIINGKCECD TIRTCNNPFE FPSQDTCLSA LKRIEEEKPD
CSKARCEVQF SPRCPEDSIL IEGYAPPGEC CPLPSRCVCN PAGCLRKVCQ PGYLNILVSK
ASGKPGECCD LYECKPVFSV DCSTVECPPV QQVVCPLDSY ETQVRLTADG CCTLPTRCEC
LTGLCGFPMC EAGTVPQIVS RGDGTPGKCC DVFECVSEGK PTCIFNSMEY YDGDMFRMDA
CRFCRCQAGV SICFSAQCGE LHCDRYYVPE GECCPVCEDP LYPVNNPAGC YANGKILAHG
DRWREDDCTF CQCINGDPHC VATACGQSCI NPVKVPGECC PVCEEPTYIT IGPPTCEVLV
NCTLTEKDCI YSFKLDQNGC RICQCKTREE LCTGLISGCS LDCSFGFQTD AHNCEICQCR
PRPKKCKPIV CDKYCPFGYL KNKHGCEICR CKKCPNLPCG KICPLGFQQN SHGCVICKCR
EATASLMPPV KTGSCLSMDG HRHENEESWH DGCRECYCHN GREMCALITC PVPSCANPTI
HPGQCCPSCP DEIIVQKPEL TSPSICHAPG GEYFVEGETW NIDSCTQCTC HSGRVLCETE
VCPPLLCQNP TRTQDSCCPQ CPDETLQPSP SSNESLPNYC KNDDGDIFLT AESWKPNVCT
SCICMDGVIR CYSESCPPVS CDRPVLRKGQ CCPYCIEDTV PKKVVCHFSG ETYADEERWD
IDSCTHCYCL QGQTLCSTVS CPPLPCAEPI NVEGSCCPMC PEMYVPEPTN IPIEKTNHRG
DVELEVPNWP TPGENDIIHI HRDMNHLQGE HRSGSGPHPS EDASVSSVAL VTIPITIALL
LIIVLLFINQ KKQWIPVSCY KAPTKPSCLN NQLVYVDCEK GTRVQVDSSQ RMLRIADPDS
RYSGFYSMQK QNNLQADNFY QTV
//
