ID   A0A218USZ1_9PASE        Unreviewed;       965 AA.
AC   A0A218USZ1;
DT   27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT   27-SEP-2017, sequence version 1.
DT   24-JAN-2024, entry version 22.
DE   SubName: Full=Dedicator of cytokinesis protein 2 {ECO:0000313|EMBL:OWK56746.1};
GN   Name=DOCK2_1 {ECO:0000313|EMBL:OWK56746.1};
GN   ORFNames=RLOC_00006914 {ECO:0000313|EMBL:OWK56746.1};
OS   Lonchura striata domestica (Bengalese finch).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC   Estrildinae; Lonchura.
OX   NCBI_TaxID=299123 {ECO:0000313|EMBL:OWK56746.1, ECO:0000313|Proteomes:UP000197619};
RN   [1] {ECO:0000313|EMBL:OWK56746.1, ECO:0000313|Proteomes:UP000197619}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=White83orange57 {ECO:0000313|EMBL:OWK56746.1};
RA   Colquitt B.M., Brainard M.S.;
RT   "Genome of assembly of the Bengalese finch, Lonchura striata domestica.";
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the DOCK family. {ECO:0000256|PROSITE-
CC       ProRule:PRU00984}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OWK56746.1}.
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DR   EMBL; MUZQ01000149; OWK56746.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A218USZ1; -.
DR   STRING; 299123.ENSLSDP00000018614; -.
DR   Proteomes; UP000197619; Unassembled WGS sequence.
DR   GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR   GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR   Gene3D; 1.20.58.740; -; 1.
DR   Gene3D; 1.25.40.410; -; 1.
DR   InterPro; IPR026791; DOCK.
DR   InterPro; IPR043161; DOCK_C_lobe_A.
DR   InterPro; IPR043162; DOCK_C_lobe_C.
DR   InterPro; IPR027357; DOCKER_dom.
DR   InterPro; IPR046769; DOCKER_Lobe_A.
DR   InterPro; IPR046770; DOCKER_Lobe_B.
DR   InterPro; IPR046773; DOCKER_Lobe_C.
DR   PANTHER; PTHR45653; DEDICATOR OF CYTOKINESIS; 1.
DR   PANTHER; PTHR45653:SF6; DEDICATOR OF CYTOKINESIS PROTEIN 2; 1.
DR   Pfam; PF06920; DHR-2_Lobe_A; 1.
DR   Pfam; PF20422; DHR-2_Lobe_B; 1.
DR   Pfam; PF20421; DHR-2_Lobe_C; 1.
DR   PROSITE; PS51651; DOCKER; 1.
PE   3: Inferred from homology;
KW   Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658};
KW   Reference proteome {ECO:0000313|Proteomes:UP000197619}.
FT   DOMAIN          272..744
FT                   /note="DOCKER"
FT                   /evidence="ECO:0000259|PROSITE:PS51651"
FT   REGION          758..917
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          930..965
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        784..800
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        818..838
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        848..864
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        865..903
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   965 AA;  109914 MW;  D9974FBDFE5DFA91 CRC64;
     MATILSQMDK DHYSTYIQAF PSRPELMDFL METFILFKDL IGKTVYPGDW VVMNMVQNRE
     FLRAINQFAT TLTEMFLSDS DFELQLWNNY FHLAVAFLTQ DSLQLENFSP AKRNAILAKY
     GDMRATIGAS IRDMWYSLGQ RKIEFIPGMV GPILEMTLVP ELELRKSTIP IFFDMMLCEH
     RLTGSFSRFE DEILRRLDSE VEGGRGDEQY MQLFKSILLS CCQSHPELAK PGEDFVRLVS
     ELLERLLDYR AVMNDENKTY SMSCTVNLLN FYKEIDRQAM YIRYLYKLKD LHISYENYTE
     GAYTLLLHAR LLTWSEESNA APVPGPHGLH LHTQRQLKEA LYNQIIEYFD QGKMWEEAIH
     ICKELAEQYE NHVFDYEMLS DILQREAKFY EKILKVLRPS PDYFAVYFYG CRCLLLGRGL
     SLISTSTPVL WDTLALLCGT GMSCHLPTLQ NKVFIYRGKE YERREDFEMQ LLSPFPNAEK
     LKSTSPPGQD ITHSPGQCIL RVHRDRAGSG SGAPFPVCAR GSFTPTDIQC FTVQPAEEAK
     VRLKGRSIPE QITNFYKANH VQRFSYSRPF KRGPNDPDNE FANMWIERTT FRTAYPLPGI
     LRWFVVTSTE TIIISPLENA IETMMKTNEK IMSEINRHQN DSSLPINPLS MLLNGIVDPA
     VMGGFTKYEK AFFQELYMQE HPEDAGKIEK LKDLIAWQIP LLAEGIRIHG QKVTEDLRPF
     HERMEQCFEQ LRAKVESQYG VREMMFFEDR RSGRPRSIAW VPDWDQPSHA GARQVGSAAP
     SDAPAGPWPS PAPLPPAAPH LSQSPHSTEA PPTPKAAHRP SESEDHRNER RENRASSIFS
     SRRQDSRQSI SELPEPKDEK WRLSCNVSES TLSAERKQPP PSQSAAGAQP SAAGSSPSPT
     GFGGRVKSAS KLSPLPRKFS PAVYETFLEQ SDAAAPGKAS PSPDGNRSLK SPPLPPPKSK
     RLSQL
//