ID A0A218UUW4_9PASE Unreviewed; 292 AA.
AC A0A218UUW4;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Thioredoxin-related transmembrane protein 2 {ECO:0000313|EMBL:OWK57416.1};
GN Name=TMX2 {ECO:0000313|EMBL:OWK57416.1};
GN ORFNames=RLOC_00010161 {ECO:0000313|EMBL:OWK57416.1};
OS Lonchura striata domestica (Bengalese finch).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Lonchura.
OX NCBI_TaxID=299123 {ECO:0000313|EMBL:OWK57416.1, ECO:0000313|Proteomes:UP000197619};
RN [1] {ECO:0000313|EMBL:OWK57416.1, ECO:0000313|Proteomes:UP000197619}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=White83orange57 {ECO:0000313|EMBL:OWK57416.1};
RA Colquitt B.M., Brainard M.S.;
RT "Genome of assembly of the Bengalese finch, Lonchura striata domestica.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004115}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004115}. Membrane
CC {ECO:0000256|ARBA:ARBA00004479}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479}. Mitochondrion membrane
CC {ECO:0000256|ARBA:ARBA00004583}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004583}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWK57416.1}.
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DR EMBL; MUZQ01000123; OWK57416.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A218UUW4; -.
DR STRING; 299123.ENSLSDP00000005530; -.
DR OrthoDB; 7109at2759; -.
DR Proteomes; UP000197619; Unassembled WGS sequence.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
DR CDD; cd02962; TMX2; 1.
DR Gene3D; 3.40.30.10; Glutaredoxin; 1.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR InterPro; IPR013766; Thioredoxin_domain.
DR InterPro; IPR039101; TMX2.
DR InterPro; IPR037463; TMX2_thioredoxin_dom.
DR PANTHER; PTHR15853; THIOREDOXIN-RELATED; 1.
DR PANTHER; PTHR15853:SF0; THIOREDOXIN-RELATED TRANSMEMBRANE PROTEIN 2; 1.
DR Pfam; PF00085; Thioredoxin; 1.
DR SUPFAM; SSF52833; Thioredoxin-like; 1.
DR PROSITE; PS51352; THIOREDOXIN_2; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000197619};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 114..134
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 132..269
FT /note="Thioredoxin"
FT /evidence="ECO:0000259|PROSITE:PS51352"
FT REGION 263..292
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 292 AA; 33455 MW; D30D7C5B57015C86 CRC64;
MAVVAPLLAL LWGLPGLCRW LAQPYYPLSA LLAAAFLIVR KVPPLCRGLP SQREDGNPCD
FDWREVEILM FLSAIVMMKN RRSITVEQHI GNIFMFSKVA NAILFFRLDI RMGLLYLTLC
IVFLMTCKPP LYMGPEYIKY FSDKTIDEEL ERDKRVTWIV EFFANWSSEC QSFAPIFADL
SLKYNCSGLQ FGKVDVGRYT DVSTRYKVST SPLTKQLPTL ILFQGGTEIM RRPQIDKKGR
AVSWTFSEEN VIREFNLNEL YQKAKKQSKP QEEGPEEPPA VPAAAQETKK DK
//
