ID A0A218UW45_9PASE Unreviewed; 654 AA.
AC A0A218UW45;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 24-JAN-2024, entry version 20.
DE SubName: Full=Integrin alpha-9 {ECO:0000313|EMBL:OWK57985.1};
GN Name=ITGA9 {ECO:0000313|EMBL:OWK57985.1};
GN ORFNames=RLOC_00008392 {ECO:0000313|EMBL:OWK57985.1};
OS Lonchura striata domestica (Bengalese finch).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Lonchura.
OX NCBI_TaxID=299123 {ECO:0000313|EMBL:OWK57985.1, ECO:0000313|Proteomes:UP000197619};
RN [1] {ECO:0000313|EMBL:OWK57985.1, ECO:0000313|Proteomes:UP000197619}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=White83orange57 {ECO:0000313|EMBL:OWK57985.1};
RA Colquitt B.M., Brainard M.S.;
RT "Genome of assembly of the Bengalese finch, Lonchura striata domestica.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479,
CC ECO:0000256|RuleBase:RU003762}; Single-pass type I membrane protein
CC {ECO:0000256|ARBA:ARBA00004479, ECO:0000256|RuleBase:RU003762}.
CC -!- SIMILARITY: Belongs to the integrin alpha chain family.
CC {ECO:0000256|ARBA:ARBA00008054, ECO:0000256|RuleBase:RU003762}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWK57985.1}.
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DR EMBL; MUZQ01000111; OWK57985.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A218UW45; -.
DR STRING; 299123.ENSLSDP00000002713; -.
DR Proteomes; UP000197619; Unassembled WGS sequence.
DR GO; GO:0008305; C:integrin complex; IEA:InterPro.
DR GO; GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
DR GO; GO:0007229; P:integrin-mediated signaling pathway; IEA:UniProtKB-KW.
DR Gene3D; 2.130.10.130; Integrin alpha, N-terminal; 1.
DR Gene3D; 2.60.40.1460; Integrin domains. Chain A, domain 2; 1.
DR InterPro; IPR013517; FG-GAP.
DR InterPro; IPR013519; Int_alpha_beta-p.
DR InterPro; IPR000413; Integrin_alpha.
DR InterPro; IPR013649; Integrin_alpha_Ig-like_1.
DR InterPro; IPR028994; Integrin_alpha_N.
DR InterPro; IPR032695; Integrin_dom_sf.
DR PANTHER; PTHR23220; INTEGRIN ALPHA; 1.
DR PANTHER; PTHR23220:SF69; INTEGRIN ALPHA-9; 1.
DR Pfam; PF01839; FG-GAP; 2.
DR Pfam; PF08441; Integrin_A_Ig_1; 1.
DR PRINTS; PR01185; INTEGRINA.
DR SMART; SM00191; Int_alpha; 5.
DR SUPFAM; SSF69318; Integrin alpha N-terminal domain; 1.
DR SUPFAM; SSF69179; Integrin domains; 1.
DR PROSITE; PS51470; FG_GAP; 4.
PE 3: Inferred from homology;
KW Cell adhesion {ECO:0000256|ARBA:ARBA00022889,
KW ECO:0000256|RuleBase:RU003762};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Integrin {ECO:0000256|ARBA:ARBA00023037, ECO:0000256|RuleBase:RU003762};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Receptor {ECO:0000256|ARBA:ARBA00023170, ECO:0000256|RuleBase:RU003762};
KW Reference proteome {ECO:0000313|Proteomes:UP000197619};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|RuleBase:RU003762}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|RuleBase:RU003762"
FT CHAIN 24..654
FT /evidence="ECO:0000256|RuleBase:RU003762"
FT /id="PRO_5011819456"
FT REPEAT 28..90
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 284..343
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 344..402
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT REPEAT 405..468
FT /note="FG-GAP"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00803"
FT DOMAIN 453..614
FT /note="Integrin alpha first immunoglubulin-like"
FT /evidence="ECO:0000259|Pfam:PF08441"
SQ SEQUENCE 654 AA; 72284 MW; 35D9AE620DEA7D85 CRC64;
MPEARRRGAR VLWTLLWAAA VRCYNVDVGR PVIFRGPNGS FFGYSVLQHY HDSTRWVLVG
APKAESKYST SVQSPGAVFK CRVHTNPDRR CTELDMGRGN SRGMLCGKTC KEDRDDEWMG
VSLARQPKAG GSVLACAHRW KNIYYETEYI LPHGFCNVIP PNLQSKGRKL LPCYEEYKKK
YGEEHGSCQA GIAGFFTEEL VIMGAPGSYY WTGTVKVLNL TDNTYYKLND DAVIARRYTY
LGYAVTAGHF SQPTTTDIVG GAPQDGGIGK VYIFRTDRQS GSLIKIFQAS GKKMGSYFGS
SLCAVDLNSD GLSDLLVGAP MFSEIRDEGQ VTVYINRGNG VLEEQLTLDG DSAYNAHFGE
SMAALGDIDD DGFPDVAIGA PKEDNYIGAV YIYHGDANGI IPQYSMKLSG QTINPKLRMF
GQSISGGVDM DSNGYPDMTV GAFLSDNVVL LRSRPVITMD ITIFLPISIN ITAPQCHDGL
QPVNCLNITA CFRFSGKHVP GAIGLNYNLT ADVVKKEKSQ QPRVYFVTSG ETAGQITEKL
QLSFMQEKCE HYLAYVKKRV KDVISPIVFE ASYSLGEHAI ERGKEDKELT ALKPILRWKK
GQKIAQRNQT VFERNCQSDD CAADLKLRGK LLLSGFANSP KYSSFQILPV ATWE
//
