ID A0A218UXL6_9PASE Unreviewed; 209 AA.
AC A0A218UXL6;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 24-JAN-2024, entry version 17.
DE SubName: Full=Retinol-binding protein 4 {ECO:0000313|EMBL:OWK58160.1};
GN Name=RBP4 {ECO:0000313|EMBL:OWK58160.1};
GN ORFNames=RLOC_00002481 {ECO:0000313|EMBL:OWK58160.1};
OS Lonchura striata domestica (Bengalese finch).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Lonchura.
OX NCBI_TaxID=299123 {ECO:0000313|EMBL:OWK58160.1, ECO:0000313|Proteomes:UP000197619};
RN [1] {ECO:0000313|EMBL:OWK58160.1, ECO:0000313|Proteomes:UP000197619}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=White83orange57 {ECO:0000313|EMBL:OWK58160.1};
RA Colquitt B.M., Brainard M.S.;
RT "Genome of assembly of the Bengalese finch, Lonchura striata domestica.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|ARBA:ARBA00004613}.
CC -!- SIMILARITY: Belongs to the calycin superfamily. Lipocalin family.
CC {ECO:0000256|ARBA:ARBA00006889, ECO:0000256|PIRNR:PIRNR036893,
CC ECO:0000256|RuleBase:RU003695}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWK58160.1}.
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DR EMBL; MUZQ01000106; OWK58160.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A218UXL6; -.
DR STRING; 299123.ENSLSDP00000024103; -.
DR Proteomes; UP000197619; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IEA:UniProt.
DR GO; GO:0019841; F:retinol binding; IEA:UniProtKB-KW.
DR GO; GO:0034632; F:retinol transmembrane transporter activity; IEA:InterPro.
DR CDD; cd00743; lipocalin_RBP_like; 1.
DR Gene3D; 2.40.128.20; -; 1.
DR InterPro; IPR012674; Calycin.
DR InterPro; IPR022271; Lipocalin_ApoD.
DR InterPro; IPR022272; Lipocalin_CS.
DR InterPro; IPR000566; Lipocln_cytosolic_FA-bd_dom.
DR InterPro; IPR002449; Retinol-bd/Purpurin.
DR PANTHER; PTHR11873; RETINOL-BINDING PROTEIN 4; 1.
DR PANTHER; PTHR11873:SF2; RETINOL-BINDING PROTEIN 4; 1.
DR Pfam; PF00061; Lipocalin; 1.
DR PIRSF; PIRSF036893; Lipocalin_ApoD; 1.
DR PIRSF; PIRSF500204; RBP_purpurin; 1.
DR PRINTS; PR00179; LIPOCALIN.
DR PRINTS; PR01174; RETINOLBNDNG.
DR SUPFAM; SSF50814; Lipocalins; 1.
DR PROSITE; PS00213; LIPOCALIN; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR036893-50};
KW Reference proteome {ECO:0000313|Proteomes:UP000197619};
KW Retinol-binding {ECO:0000256|ARBA:ARBA00023072};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Signal {ECO:0000256|PIRNR:PIRNR036893}.
FT SIGNAL 1..34
FT /evidence="ECO:0000256|PIRNR:PIRNR036893"
FT CHAIN 35..209
FT /evidence="ECO:0000256|PIRNR:PIRNR036893"
FT /id="PRO_5013437275"
FT DOMAIN 55..180
FT /note="Lipocalin/cytosolic fatty-acid binding"
FT /evidence="ECO:0000259|Pfam:PF00061"
FT BINDING 132
FT /ligand="substrate"
FT /evidence="ECO:0000256|PIRSR:PIRSR036893-51"
FT DISULFID 38..194
FT /evidence="ECO:0000256|PIRSR:PIRSR036893-50"
FT DISULFID 104..208
FT /evidence="ECO:0000256|PIRSR:PIRSR036893-50"
FT DISULFID 154..163
FT /evidence="ECO:0000256|PIRSR:PIRSR036893-50"
SQ SEQUENCE 209 AA; 23923 MW; 4BF7A5C5A0E081F5 CRC64;
MLFSVCCRDR MAHTERALPW LLLLSLALMG SSTAERDCRV SSFKVKENFD KTRYSGTWYA
MAKKDPEGLF LQDNVVAQFT VDENGQMTAT AKGRVRLFNN WDVCADMIGS FTDTEDPAKF
KMKYWGVASF LQKGNDDHWV VDTDYDTYAL HYSCRQLNAD GTCADSYSFV FSRDPKGLPP
DALKIVRQRQ IELCLDRKYR IIAHNGFCS
//
