ID   A0A218V3L1_9PASE        Unreviewed;       757 AA.
AC   A0A218V3L1;
DT   27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT   27-SEP-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Echinoderm microtubule-associated protein-like 1 {ECO:0000313|EMBL:OWK60300.1};
GN   Name=EML1 {ECO:0000313|EMBL:OWK60300.1};
GN   ORFNames=RLOC_00012980 {ECO:0000313|EMBL:OWK60300.1};
OS   Lonchura striata domestica (Bengalese finch).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC   Estrildinae; Lonchura.
OX   NCBI_TaxID=299123 {ECO:0000313|EMBL:OWK60300.1, ECO:0000313|Proteomes:UP000197619};
RN   [1] {ECO:0000313|EMBL:OWK60300.1, ECO:0000313|Proteomes:UP000197619}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=White83orange57 {ECO:0000313|EMBL:OWK60300.1};
RA   Colquitt B.M., Brainard M.S.;
RT   "Genome of assembly of the Bengalese finch, Lonchura striata domestica.";
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May modify the assembly dynamics of microtubules, such that
CC       microtubules are slightly longer, but more dynamic.
CC       {ECO:0000256|ARBA:ARBA00003210}.
CC   -!- SIMILARITY: Belongs to the WD repeat EMAP family.
CC       {ECO:0000256|ARBA:ARBA00006489}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OWK60300.1}.
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DR   EMBL; MUZQ01000063; OWK60300.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A218V3L1; -.
DR   STRING; 299123.ENSLSDP00000011310; -.
DR   Proteomes; UP000197619; Unassembled WGS sequence.
DR   CDD; cd21947; TD_EMAP1; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   InterPro; IPR024977; Apc4-like_WD40_dom.
DR   InterPro; IPR005108; HELP.
DR   InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR001680; WD40_rpt.
DR   PANTHER; PTHR13720:SF22; ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 1; 1.
DR   PANTHER; PTHR13720; WD-40 REPEAT PROTEIN; 1.
DR   Pfam; PF12894; ANAPC4_WD40; 1.
DR   Pfam; PF03451; HELP; 1.
DR   Pfam; PF00400; WD40; 4.
DR   SMART; SM00320; WD40; 10.
DR   SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 2.
DR   PROSITE; PS50082; WD_REPEATS_2; 3.
DR   PROSITE; PS50294; WD_REPEATS_REGION; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000197619};
KW   WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT   DOMAIN          130..201
FT                   /note="HELP"
FT                   /evidence="ECO:0000259|Pfam:PF03451"
FT   REPEAT          481..522
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   DOMAIN          535..625
FT                   /note="Anaphase-promoting complex subunit 4-like WD40"
FT                   /evidence="ECO:0000259|Pfam:PF12894"
FT   REPEAT          610..641
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REPEAT          722..757
FT                   /note="WD"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          82..120
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        82..109
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   757 AA;  83788 MW;  2894B482C5EB6222 CRC64;
     MSDCEGLPVD DSASAASSME VTDRIASLEQ RVQMQEDDIQ LLKSALADVV RRLNITEEQQ
     AMQNKKGPTK ARPLVQTLPL RTTVNNGTVL PKKPSGSLPS PSGTRKETVS PAAKSKPKEP
     MFSAEEGYVK MFLRGRPVTM YMPKEQVESY NLEAKVELPA KRLKLEWVYG YRGRDCRSNL
     YLLPTGETVY FIASVVVLFN VEEQLQRHYT GHNDDVKCLA VHPDRITIAT GQVAGTSKDG
     KQLPPHVRVW DSVTLNTLHV IGMGFFDRAV TCIAFSKSNG GSSLCSVDDS NDHVLSVWDW
     QKEEKLADVK CSNEAVFAAD FHPTDTNIIV TCGKSHLYFW TLEGNSLIKK QGLFEKQEKP
     KFVLCVTFSE NGDTITGDSS GNILVWGKGT NRISHAVQGA HEGGIFALCM LRDGTLVSGG
     GKDRKLISWN GNYQKIHKTE IPEQFGPIRT VAEGKGDVVL IGTTRNFVLQ GTLSGDFFPI
     TQGHTDELWG LAVHSSKPQF FTCGHDKHIT LWDATTHHPI WNKIIEDPAQ SSGFHPSASV
     VAVGTLTGRW FVFDTETKDL VTVHTDGNEQ LSVMRYSPDG NFLAIGSHDN CIYIYGVSEN
     GRKYTRIGKC SGHSSFITHL DWSVNSQYLV SNSGDYEILY WIPSACKQVV SVETTRDIEW
     ATYTCTLGFH VFGVWPEGSD GTDINAVCRS HGRKLLSTGD DFGKVHLFSY PCSQFRAPSH
     VYGGHSSHVT NVDFLCEDTH LISTGGKDTS IMQWRVI
//