ID   A0A218V4V7_9PASE        Unreviewed;       705 AA.
AC   A0A218V4V7;
DT   27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT   27-SEP-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Xaa-Pro aminopeptidase 2 {ECO:0000313|EMBL:OWK60642.1};
GN   Name=XPNPEP2 {ECO:0000313|EMBL:OWK60642.1};
GN   ORFNames=RLOC_00014680 {ECO:0000313|EMBL:OWK60642.1};
OS   Lonchura striata domestica (Bengalese finch).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC   Estrildinae; Lonchura.
OX   NCBI_TaxID=299123 {ECO:0000313|EMBL:OWK60642.1, ECO:0000313|Proteomes:UP000197619};
RN   [1] {ECO:0000313|EMBL:OWK60642.1, ECO:0000313|Proteomes:UP000197619}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=White83orange57 {ECO:0000313|EMBL:OWK60642.1};
RA   Colquitt B.M., Brainard M.S.;
RT   "Genome of assembly of the Bengalese finch, Lonchura striata domestica.";
RL   Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase M24B family.
CC       {ECO:0000256|ARBA:ARBA00008766}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OWK60642.1}.
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DR   EMBL; MUZQ01000056; OWK60642.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A218V4V7; -.
DR   STRING; 299123.ENSLSDP00000002192; -.
DR   Proteomes; UP000197619; Unassembled WGS sequence.
DR   GO; GO:0070006; F:metalloaminopeptidase activity; IEA:InterPro.
DR   CDD; cd01085; APP; 1.
DR   Gene3D; 3.90.230.10; Creatinase/methionine aminopeptidase superfamily; 2.
DR   Gene3D; 3.40.350.10; Creatinase/prolidase N-terminal domain; 2.
DR   InterPro; IPR029149; Creatin/AminoP/Spt16_NTD.
DR   InterPro; IPR036005; Creatinase/aminopeptidase-like.
DR   InterPro; IPR000587; Creatinase_N.
DR   InterPro; IPR000994; Pept_M24.
DR   InterPro; IPR033740; Pept_M24B.
DR   InterPro; IPR032416; Peptidase_M24_C.
DR   PANTHER; PTHR43763; XAA-PRO AMINOPEPTIDASE 1; 1.
DR   PANTHER; PTHR43763:SF4; XAA-PRO AMINOPEPTIDASE 2; 1.
DR   Pfam; PF01321; Creatinase_N; 1.
DR   Pfam; PF16189; Creatinase_N_2; 1.
DR   Pfam; PF00557; Peptidase_M24; 1.
DR   Pfam; PF16188; Peptidase_M24_C; 1.
DR   SUPFAM; SSF55920; Creatinase/aminopeptidase; 1.
DR   SUPFAM; SSF53092; Creatinase/prolidase N-terminal domain; 1.
PE   3: Inferred from homology;
KW   Aminopeptidase {ECO:0000313|EMBL:OWK60642.1};
KW   Hydrolase {ECO:0000313|EMBL:OWK60642.1};
KW   Protease {ECO:0000313|EMBL:OWK60642.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000197619}.
FT   DOMAIN          91..222
FT                   /note="Creatinase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF01321"
FT   DOMAIN          467..601
FT                   /note="Peptidase M24"
FT                   /evidence="ECO:0000259|Pfam:PF00557"
FT   DOMAIN          613..677
FT                   /note="Peptidase M24 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF16188"
FT   REGION          25..44
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          58..82
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   705 AA;  77992 MW;  FEB1FD2B9ED033C1 CRC64;
     MSRSGENAAR AMEAVSVEGW WQRCNESKPN SGLEQRSSRP PGCSLRLPGV AVPTGCAAGR
     APQAPSTRND IRACSADPPY LPRTATNTTA RLATLRGIMR THSVHAYIVP STDAHMSEYI
     SERDARLGWL TGFTGSAGTA VVTQDKAALW TDSRYWTQAE RELDCNWELQ RTISIESIGM
     WILKAVPAEG KVSLDPFLFS IDTWKSYSRA LHGSGRTLHP LETNLVDQAW GDQRPPPSSS
     EIYSLPAEFT GRSWQEKVAG IRQRMEQHVR RPTAVLLSGL EETAWLFNLR GDDIPYNPVF
     YSYTLLTNTT ISLFVEESRL SAAARESLRS GCPGPLCVEL QEYGQVSAHL RRYAQGSVTV
     WLGTEYTTYG LYAIIPQEKL LEESYSPVMM AKAVKNTHEQ EMLRAAHVRD AVAVIQYLLW
     LEKAVPQGHV DEFSGAQQID AFRWAQEHSR GPSFQSISAS GLNAALAHYR DGTTDITRTV
     HWGEPTPLQK EAYTRVLMGN IDLSRLIFPS NTAGSLAPVP PLHSPGRTVE SFARRALWNV
     GLNYGHGTGH GIGNFLSVHE WPVGFQSNNV PLEAGMFTSI EPGYYQDGEF GIRIEDVALV
     VEAQTEHQSG EKPFLTFEVV SLVPYDRNLI NLSLLSPEQI RYLNSYYERI RAHVGPELRR
     QQLEEAYAWL QESTEPFPMS SAGPAAAGTL ALASLLSVLL SGLGA
//