ID A0A218VC01_9PASE Unreviewed; 425 AA.
AC A0A218VC01;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Cysteine-rich with EGF-like domain protein 1 {ECO:0000313|EMBL:OWK63575.1};
GN Name=CRELD1 {ECO:0000313|EMBL:OWK63575.1};
GN ORFNames=RLOC_00009681 {ECO:0000313|EMBL:OWK63575.1};
OS Lonchura striata domestica (Bengalese finch).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Lonchura.
OX NCBI_TaxID=299123 {ECO:0000313|EMBL:OWK63575.1, ECO:0000313|Proteomes:UP000197619};
RN [1] {ECO:0000313|EMBL:OWK63575.1, ECO:0000313|Proteomes:UP000197619}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=White83orange57 {ECO:0000313|EMBL:OWK63575.1};
RA Colquitt B.M., Brainard M.S.;
RT "Genome of assembly of the Bengalese finch, Lonchura striata domestica.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the CRELD family.
CC {ECO:0000256|ARBA:ARBA00005897}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWK63575.1}.
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DR EMBL; MUZQ01000011; OWK63575.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A218VC01; -.
DR STRING; 299123.ENSLSDP00000010824; -.
DR OrthoDB; 337149at2759; -.
DR Proteomes; UP000197619; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR CDD; cd00054; EGF_CA; 1.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR001881; EGF-like_Ca-bd_dom.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR000152; EGF-type_Asp/Asn_hydroxyl_site.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR006212; Furin_repeat.
DR InterPro; IPR009030; Growth_fac_rcpt_cys_sf.
DR InterPro; IPR002049; LE_dom.
DR PANTHER; PTHR24038:SF13; PROTEIN DISULFIDE-ISOMERASE; 1.
DR PANTHER; PTHR24038; STABILIN; 1.
DR Pfam; PF07645; EGF_CA; 2.
DR SMART; SM00181; EGF; 3.
DR SMART; SM00179; EGF_CA; 2.
DR SMART; SM00261; FU; 2.
DR SUPFAM; SSF57184; Growth factor receptor domain; 1.
DR PROSITE; PS00010; ASX_HYDROXYL; 1.
DR PROSITE; PS00022; EGF_1; 1.
DR PROSITE; PS50026; EGF_3; 1.
DR PROSITE; PS01187; EGF_CA; 2.
DR PROSITE; PS01248; EGF_LAM_1; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00076};
KW EGF-like domain {ECO:0000256|ARBA:ARBA00022536, ECO:0000256|PROSITE-
KW ProRule:PRU00076}; Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000197619};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..34
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 35..425
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5012916930"
FT TRANSMEM 368..386
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 393..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 151..193
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DISULFID 183..192
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00076"
SQ SEQUENCE 425 AA; 46099 MW; EEDD7CB23FB35AF9 CRC64;
MAPLPRSPGR GGPGLGAALL GAALLAGVLL AVHADPDSHR DGAEPCRTCR GLADSFIRGL
ERTEHEGFGG GNTAWEEEKL SKYQHSETRL LEVLEGVCAP SDFACHQLLE RSEEHVEQWW
FHEQQQHPDF FQWLCVDSLM LCCPPGTYGP DCRSCAGGPQ QPCSGNGRCD GDGTRRGTGL
CVCSPGYGGP FCAECGDGYY EASRNKSHLV CAECYQACGR CTGPEDSSCL RCKRGWVLHE
HRCIDIDECG TEMAHCRANQ YCVNTEGSYE CRDCSTACIG CMGAGPARCK KCNKGYWRDG
AKCLDVDECA SAEEPVCTGV QEVCENTEGS YRCVCAQGHV RRDGQCVEDK PPDAPEKGFF
DDVTDDEVVV LQQMFFGVMI CALATLAAKG DMVFTAIFIG AVAAMAGYWL SDRSDRVLDG
FMKGR
//
