ID A0A218VDU7_9PASE Unreviewed; 833 AA.
AC A0A218VDU7;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE SubName: Full=Zinc fingers and homeoboxes protein 2 {ECO:0000313|EMBL:OWK64028.1};
GN Name=ZHX2 {ECO:0000313|EMBL:OWK64028.1};
GN ORFNames=RLOC_00005265 {ECO:0000313|EMBL:OWK64028.1};
OS Lonchura striata domestica (Bengalese finch).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Estrildidae;
OC Estrildinae; Lonchura.
OX NCBI_TaxID=299123 {ECO:0000313|EMBL:OWK64028.1, ECO:0000313|Proteomes:UP000197619};
RN [1] {ECO:0000313|EMBL:OWK64028.1, ECO:0000313|Proteomes:UP000197619}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=White83orange57 {ECO:0000313|EMBL:OWK64028.1};
RA Colquitt B.M., Brainard M.S.;
RT "Genome of assembly of the Bengalese finch, Lonchura striata domestica.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PROSITE-ProRule:PRU00108, ECO:0000256|RuleBase:RU000682}.
CC -!- SIMILARITY: Belongs to the ZHX family. {ECO:0000256|ARBA:ARBA00007440}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWK64028.1}.
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DR EMBL; MUZQ01000006; OWK64028.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A218VDU7; -.
DR STRING; 299123.ENSLSDP00000004414; -.
DR OrthoDB; 5350395at2759; -.
DR Proteomes; UP000197619; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR CDD; cd00086; homeodomain; 4.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 1.
DR Gene3D; 1.10.10.60; Homeodomain-like; 4.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR001356; Homeobox_dom.
DR InterPro; IPR041057; ZHX_Znf_C2H2.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR15467:SF5; ZINC FINGERS AND HOMEOBOXES PROTEIN 2; 1.
DR PANTHER; PTHR15467; ZINC-FINGERS AND HOMEOBOXES RELATED; 1.
DR Pfam; PF00046; Homeodomain; 3.
DR Pfam; PF18387; zf_C2H2_ZHX; 1.
DR SMART; SM00389; HOX; 4.
DR SMART; SM00355; ZnF_C2H2; 2.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 2.
DR SUPFAM; SSF46689; Homeodomain-like; 4.
DR PROSITE; PS50071; HOMEOBOX_2; 4.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00108};
KW Homeobox {ECO:0000256|ARBA:ARBA00023155, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00108}; Reference proteome {ECO:0000313|Proteomes:UP000197619};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 107..135
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 282..321
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DOMAIN 445..495
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DOMAIN 535..579
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DOMAIN 634..684
FT /note="Homeobox"
FT /evidence="ECO:0000259|PROSITE:PS50071"
FT DNA_BIND 284..322
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT DNA_BIND 447..496
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT DNA_BIND 537..580
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT DNA_BIND 636..685
FT /note="Homeobox"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00108"
FT REGION 1..52
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 183..209
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 698..833
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..15
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 191..209
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 704..753
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 767..783
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 833 AA; 92260 MW; 9709B8ACD8DC1CC5 CRC64;
MASKRKSTTP CMVRTSEVME QEGAEGAETP KDKGTCASQQ DSKKNWPSEN SVKDCEVVEA
KPAGENQSKK PQGGYECKYC PYSTQNLNEF TEHVDTQHPN VILNPLYVCA ECNFTTKKYD
SLSDHNTKYH PGETNFKLKL IKRNNQTVLE QSIETATNDV TVTSSGLENA ECDDSLHGGI
SANKAPAMKL GKPKGETKKG CKKPEEGVTE NHVDGALPRI ITEATEAIAC INGDLLHDVL
AHVMPSVQLP PNINLVPKVP VPLNSTKYNS ALDTNATMIN SFNKFPYPTQ AELSWLTAAS
KHPEEQIRIW FATQRLKHGI SWSPEEVEEA RKKMFNGTIQ AVPQTITVLP APLATAKMPQ
PIIQTALPCQ ILGQTGLVLT PVSNGSTVSC SPITLAVAPN QGQKRTIQTV SSAPEAKRPH
IVQVPEIPAK VTAVPVTPAS ERKKTKEQIA ELKASFMASQ FPDDAEVYRL IEATGLSRSE
IKKWFSDHRY RSQRGIVQIP GDALGKDQIA PPAGRHGRSF HPYTDFTPQR FKEKTQEQLR
ALEESFLKCS FPTQGELDRL RVETKLSRRE IDSWFSERRK IRDSMEQAVL DSMGSYRKIK
DQGTPNGAIS QAELLSSSQL PGALSGSSST LKKTQEQIHL LKSTFARTQW PSPQEYDQLA
SQTGLTRTEI VRWFKENRSS LRTGSLKWID QYQQQYAADG HNKQSQKKNS KHIESPKNGN
EVSRQHYQEH KKLNEENGGK PVVRAKRDCE PLKDSLLGNQ AEGVDRLECS NSHDGHGSEE
NEEPAEVNWV EVTVGEDDAA SDCTDGWSQT APEGHTELAD LDSESIPGDN SHV
//
