ID A0A218WA61_PUNGR Unreviewed; 1032 AA.
AC A0A218WA61;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=DNA repair protein RAD5A isoform X2 {ECO:0000313|RefSeq:XP_031400925.1};
GN Name=LOC116210918 {ECO:0000313|RefSeq:XP_031400925.1};
GN ORFNames=CDL15_Pgr025149 {ECO:0000313|EMBL:OWM68962.1};
OS Punica granatum (Pomegranate).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Myrtales; Lythraceae; Punica.
OX NCBI_TaxID=22663 {ECO:0000313|EMBL:OWM68962.1, ECO:0000313|Proteomes:UP000197138};
RN [1] {ECO:0000313|Proteomes:UP000197138}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Dabenzi {ECO:0000313|Proteomes:UP000197138};
RX PubMed=28654223; DOI=10.1111/tpj.13625;
RA Qin G., Xu C., Ming R., Tang H., Guyot R., Kramer E.M., Hu Y., Yi X.,
RA Qi Y., Xu X., Gao Z., Pan H., Jian J., Tian Y., Yue Z., Xu Y.;
RT "The pomegranate (Punica granatum L.) genome and the genomics of
RT punicalagin biosynthesis.";
RL Plant J. 91:1108-1128(2017).
RN [2] {ECO:0000313|EMBL:OWM68962.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC TISSUE=Fresh leaf {ECO:0000313|EMBL:OWM68962.1};
RA Xu C.;
RT "The pomegranate genome and the genomics of punicalagin biosynthesis.";
RL Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|RefSeq:XP_031400925.1}
RP IDENTIFICATION.
RC TISSUE=Leaf {ECO:0000313|RefSeq:XP_031400925.1};
RG RefSeq;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the SNF2/RAD54 helicase family. RAD16 subfamily.
CC {ECO:0000256|ARBA:ARBA00008438}.
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DR EMBL; MTKT01004939; OWM68962.1; -; Genomic_DNA.
DR RefSeq; XP_031400925.1; XM_031545065.1.
DR Proteomes; UP000197138; Unassembled WGS sequence.
DR Proteomes; UP000515151; Chromosome 6.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR GO; GO:0016818; F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0008152; P:metabolic process; IEA:UniProt.
DR CDD; cd18008; DEXDc_SHPRH-like; 1.
DR CDD; cd18793; SF2_C_SNF; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR014905; HIRAN.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR038718; SNF2-like_sf.
DR InterPro; IPR049730; SNF2/RAD54-like_C.
DR InterPro; IPR000330; SNF2_N.
DR InterPro; IPR015940; UBA.
DR InterPro; IPR009060; UBA-like_sf.
DR InterPro; IPR001841; Znf_RING.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR InterPro; IPR017907; Znf_RING_CS.
DR PANTHER; PTHR45626:SF45; DNA REPAIR PROTEIN RAD5A; 1.
DR PANTHER; PTHR45626; TRANSCRIPTION TERMINATION FACTOR 2-RELATED; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF08797; HIRAN; 1.
DR Pfam; PF00176; SNF2-rel_dom; 1.
DR Pfam; PF13920; zf-C3HC4_3; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SMART; SM00910; HIRAN; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00165; UBA; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF46934; UBA-like; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS50030; UBA; 1.
DR PROSITE; PS00518; ZF_RING_1; 1.
DR PROSITE; PS50089; ZF_RING_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00175}.
FT DOMAIN 5..47
FT /note="UBA"
FT /evidence="ECO:0000259|PROSITE:PS50030"
FT DOMAIN 411..626
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 797..837
FT /note="RING-type"
FT /evidence="ECO:0000259|PROSITE:PS50089"
FT DOMAIN 870..1032
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 48..116
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 48..75
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1032 AA; 115062 MW; B725A55EF2475EED CRC64;
MGSKATEEQL STVRSVVGMD YTDMDIIRAL HLANNDVTAA VNIIFDTPNF SSKGVPQMPR
NPRVSSHSSQ ADNRRASLKP DPVDNGVARA TDDSRMNSVA GESAVGDGRE GSGSTESDWW
FVGGGEVAGL STCKGRRVKS GDEVTFTFPS KKSLSSPSPG KIVKGRSLAA CSEIVRFSTK
DHGEIGRIPN EWARCLLPLV RDKKVRIEGF CKSAPDTLSI MDTVLLSLSV YINSSMFCKQ
HHTSLKATLN SADESVVHPL PNLFRLLGLT PFKRAEYTPS DLHTRKRPLD MKVSSGLPAA
LSAVNKNSNL SRNGEEAENE VALLDSDVDK IVGVQENSEL EEMEPPCTLQ CELRPYQKQA
LYWMVHLEKG RCMVESATTL HPCWEAYRLA DKRNLVVYLN AFSGDATTEF PSTLQMARGG
ILADSMGLGK TIMTLSLLLA HSGRGKLPRS QSTSQISNES AEDALELSLH QSKEATKLLG
FNKLVKQRNV LASGGSLIVC PMTLLGQWKA EIESHAQPGS LSIYTHYGQS RPKDAKILSQ
SDVVITTYGI LASEFSSENA EENGGLFSVR WFRVVLDEAH TIKSSKGQIS LAAAALEADR
RWCLTGTPIQ NSLEDIYSLL RFLRVEPWGN WAWWNKLIQK PFEEGDERGL KLVQSILKPI
MLRRTKFTTD QEGRPILVLP PADIQVIYCD LTEAERDFYE ALFKKSKVKF DKFVEQGRVL
HNYASILELL LRLRQCCDHP FLVMSRGDTQ EFADLNKLAK RFLKGSADVL DKEGKVVSRA
YIQEVLEELR KGEQGECPIC LEAFEDAVLT PCAHRLCREC LLASWRNSNS GLCPVCRKII
SRQDLITAPT ESRFQIDIEK NWVESSKVAV LLHELDNLRS LGSKSIVFSQ WTAFLDLLQI
PLSRNKIPFL RLDGSLNQQQ RENLIRQFSE DSDIPVLLMS LKAGGVGINL TAASNAFVMD
PWWNPAVEEQ AVMRIHRIGQ TKRVMIKRFI VKGTVEERME ALQARKQRLI SGALTDQEVR
SARIEELKML FT
//
