ID   A0A218X448_PUNGR        Unreviewed;      1198 AA.
AC   A0A218X448;
DT   27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT   27-SEP-2017, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN   ORFNames=CDL15_Pgr003303 {ECO:0000313|EMBL:OWM79132.1};
OS   Punica granatum (Pomegranate).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Myrtales; Lythraceae; Punica.
OX   NCBI_TaxID=22663 {ECO:0000313|EMBL:OWM79132.1, ECO:0000313|Proteomes:UP000197138};
RN   [1] {ECO:0000313|Proteomes:UP000197138}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Dabenzi {ECO:0000313|Proteomes:UP000197138};
RX   PubMed=28654223; DOI=10.1111/tpj.13625;
RA   Qin G., Xu C., Ming R., Tang H., Guyot R., Kramer E.M., Hu Y., Yi X.,
RA   Qi Y., Xu X., Gao Z., Pan H., Jian J., Tian Y., Yue Z., Xu Y.;
RT   "The pomegranate (Punica granatum L.) genome and the genomics of
RT   punicalagin biosynthesis.";
RL   Plant J. 91:1108-1128(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OWM79132.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; MTKT01002492; OWM79132.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A218X448; -.
DR   Proteomes; UP000197138; Unassembled WGS sequence.
DR   GO; GO:0009536; C:plastid; IEA:UniProtKB-KW.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0006952; P:defense response; IEA:InterPro.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 2.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR042197; Apaf_helical.
DR   InterPro; IPR044974; Disease_R_plants.
DR   InterPro; IPR032675; LRR_dom_sf.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   PANTHER; PTHR11017:SF580; DISEASE RESISTANCE-LIKE PROTEIN DSC1; 1.
DR   PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR   Pfam; PF00931; NB-ARC; 2.
DR   Pfam; PF01582; TIR; 2.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SMART; SM00382; AAA; 2.
DR   SMART; SM00255; TIR; 1.
DR   SUPFAM; SSF52058; L domain-like; 2.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   PROSITE; PS50104; TIR; 1.
PE   4: Predicted;
KW   NAD {ECO:0000256|ARBA:ARBA00023027}.
FT   DOMAIN          610..773
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|PROSITE:PS50104"
SQ   SEQUENCE   1198 AA;  136449 MW;  7B899FE01FDA956D CRC64;
     MIMPIFLDVT PDEVKYQTGS YAEAFTQHGE NYDFETVQEW RNALQEVVKL KGLELKKEAN
     GKHGEFIKKV LAMVLNCLKK AYLNVNDLLV GIDDHVEAVK KLLELGKEGV QIVGIWGMGG
     IGKTTLAKVV YNQLLKKFES SGFLNDIRET SSQQHKGLPY LQSKLLSDIL NREREDFANT
     NEGTQELKNR LRDRKAIILL DDVDQVDQLK ALAGDLAWFS PESRIIVTTR EKTVLDQFRI
     KNIYELTLLS AEQAFELFCR HAFIKGSPTP DFIDLSWDIV RTTGRLPLAL EVIGSSLSTS
     SGRKDLWQGT LKKLEKKPPK EVQDTLRISY NGLDHEEREI FLDIACFFIG IDARIAKPMW
     DDCEFFPGVG IEILLLKSLI KIKKDHRLWM HDQLRDLGRV IVEEENYKES RLRSRLWHSK
     VVMHVLERQP EEGMTNVEAI SLEGYQFRSE DLCFKDDQFR NLPNLRILLL DKASLSGNFE
     RIIPNLRWLS WHLCNFNAML PTNLNLKNLV VLDLSRSMVS EDWAGWSLMK VAAKLKVLDL
     TECRHLTKTP SFSAFSALEK LILRSCRNLV SVDPSIEQLS ALVSLDIRDC TKLEYLPRLG
     SMDALTELLV DYEVFLSFGG LDDSEGFTDQ LYHHLKDVGV HTVRDNGKLR VAEEIGPELM
     MAIKQSKIYI PILSKGYALS TWCLTEVAEM MKLEEETKHR IMPIFLDVTP NEVQHQTGSY
     AEAFAQHEGN YDSETVQEWR DALQKVVKLG GLEFKKEANG KHEEFIKKVL ARVVMAYLEV
     NDMVVGIIDH FKVVKTLLEL GKEGVQIVGI WGMGGIGKTT LAKVVYSQLL GKFESSCFLN
     NIRGTSSQPK GLEYLQSKLL SDILNCERED FANTNEGIQQ LKNRLRDKKA IILLDDVDQQ
     EICLDIACFF IGKDARIAKS MWDDCDFFPE IAIEILLSKS LIKITDDSRL WMHDQLRDLG
     RLIVEKENYK EPRLRSRLWQ GEVAMRVLER QPEEGRTTVE AISLEGYQFR SEDLCFKDDQ
     FKNLPNLRIL LLDKASLSGN FEGILPNLRW LSWHFCNFSP TLPTNLNLKN LVVLDLSKSM
     VSEDWAGWSL MKVAAKLKVL DLTECGHLTR TPGFSAFPAL ERLILRSCCN LVSVDPSIEQ
     LSALLSLDIR DCTKLEYLPQ LGSMDALTEL LVDGTSIQEL PVLRGTDKLG NLEALGSN
//