ID A0A218XPQ1_PUNGR Unreviewed; 2152 AA.
AC A0A218XPQ1;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN ORFNames=CDL15_Pgr015804 {ECO:0000313|EMBL:OWM86768.1};
OS Punica granatum (Pomegranate).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Myrtales; Lythraceae; Punica.
OX NCBI_TaxID=22663 {ECO:0000313|EMBL:OWM86768.1, ECO:0000313|Proteomes:UP000197138};
RN [1] {ECO:0000313|Proteomes:UP000197138}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Dabenzi {ECO:0000313|Proteomes:UP000197138};
RX PubMed=28654223; DOI=10.1111/tpj.13625;
RA Qin G., Xu C., Ming R., Tang H., Guyot R., Kramer E.M., Hu Y., Yi X.,
RA Qi Y., Xu X., Gao Z., Pan H., Jian J., Tian Y., Yue Z., Xu Y.;
RT "The pomegranate (Punica granatum L.) genome and the genomics of
RT punicalagin biosynthesis.";
RL Plant J. 91:1108-1128(2017).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWM86768.1}.
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DR EMBL; MTKT01001080; OWM86768.1; -; Genomic_DNA.
DR Proteomes; UP000197138; Unassembled WGS sequence.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 4.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 6.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR025875; Leu-rich_rpt_4.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR PANTHER; PTHR11017:SF580; DISEASE RESISTANCE-LIKE PROTEIN DSC1; 1.
DR PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR Pfam; PF12799; LRR_4; 1.
DR Pfam; PF00931; NB-ARC; 2.
DR Pfam; PF01582; TIR; 5.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00369; LRR_TYP; 4.
DR SMART; SM00255; TIR; 4.
DR SUPFAM; SSF52058; L domain-like; 3.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 5.
DR PROSITE; PS51450; LRR; 1.
DR PROSITE; PS50104; TIR; 4.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Plant defense {ECO:0000256|ARBA:ARBA00022821};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 149..314
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT DOMAIN 329..491
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT DOMAIN 510..679
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT DOMAIN 941..1107
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
FT REGION 2104..2152
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2127..2141
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2152 AA; 242152 MW; D3CDA9B0C770351C CRC64;
MAFSESSSSA AGAYDYDVFV SFKGSDVRLG FVDVLYHGLA NSGVRVFRDE EELAGGDYIS
DRGTIGESFA CHEERGVDPD RIQTWRQALR EVASLKGWEL RGHGFSEVVK RIVSEVLRIL
QMDVSESSQV LPISQMDVSE SSSSDTGAYD YDVFLSFRGS DVRLGFADVL YHGLTNAGVR
VFRDDEGLGR GDYIPDALLQ AMKRSRISIP IFSKDYASSR YLLEEVVGML DCRKLEGHVV
IPIFYDVDPI DVRMQRGTIG ESFASHEERG VDPDRIQTWR QALHEVTSLR GWELRGHGFS
EVVKRIVSEV LRILKMDVSE SSSSAAGAYD FDVFLSFRGS DVRLGFADVL YHGLMNAGVR
VFREDEGLAG GDYITDALLQ AMKRSRISIP IFSKNYASSR FLLEEVVRMV ECREREGHMV
IPIFYDVDPR DVRKQRGIIG ESFVRHEKRG VDPDRIQTWR QALQEVASLK GWELHDNGSL
GEVVKRIVSD VLRILQMDVS ESSSSDAGAY DYEVFLSFRG SDVRLGIADV LYHGLTNAGV
RVFRDDEGLV RGDLLPDAFL QGIKRSRISI PIFSKNYASS RFCLEEVVGM LECREQEGHM
VIPIFYDVDP SDVRKQRGTI GESFAGHEKR GVDLDRIQTW RQALQEAASL SGWELHDNGF
DRSLSEVVKR IVSEVLRILQ MDRPRLPRLL VGFDDRVEAV MNLLDVNAGG VRMVGIYGMG
GVGKTTLAKA VYNRLYNLFG ESPREPGERS RLWNHNEAFD VLKNRKGTGR VEALCLTFSD
DSCNSFTSSE FDGLSNLRFL RLDRAGIQGD TGDRLSRLRW LDWEGCKKLD DLLNLHLEKL
VVLDLSDSQV TGDPNTWIEV MKMASNLRVL LLNSCSKLRI SPCFPAEMRL EILSFEGCTQ
LMEIDPSIGN LKELKYLNLN FCVRIDHLPE ELDITSGTLA THFEVFLSFS THNEIASSLY
EDMKSAGISV FGVDDELNED KEVGKKLFWA IDNSEICIPI FTKDYASHVW CLRGLSHMME
CQRYSVGQQV VPIFYDVEPS DVKLETDLYI NALKEHKENF PVDTVRQWEE SLREVAELKG
WKCKAEGFKR YSKFVVSATL NKLKGKHGNV LVGLHGQAEE LKRVLDLESR DVLFVGIHGI
GGIGKTTLAK AVFDQLFTHF EGYSFLRDIR ETSKHKGLKY LQDQLLRDIL GADTDYGIRI
ISHRFLEKKV LIVLDDVDDR GQIKKLVGKS NRFAAGSRII VTTRDINVLA VEHEARDGRF
MEWPEEVRPF KMEGMKSSEA LQLFRSHAFG KVLHPDDYLS TCEQVVSALR GLPLALEIIG
SSLNRKPANV WKATMEKLEN PPDQELHSKL MISYEALDNE AKEIFLDIVC FFNGREKSTA
IYMWDACEHF PEEKLEVLIF TSFIKILGDN RLWMHDEVRD FGRKIVSGGT VIDSAKGSRL
WVNKEVLDVL RSKEENGNVQ GLRLHFDEFL RECTFPNEEL GRLPNLRFLE LSGFPFAVKR
GVPKLRWLSW HFCPPDVAAT NLHLENLTIL DLSHSRIGDH QLGESGQLGK AKNLKVLNLT
SCKSITKTPI FSECMILERL ILEDCENLVE IDISIGKLKQ LVHLNLKGCN SLKALPDELG
SANALTEIVM KGNSQSFNLQ ESITGLTSLL VLEIVHMKIV NPLRIGKSES LERLTLSECT
GIKELPESCQ FFQSLVMLDL SWTEVTKLPD SIGDMKKLKV INMEYSLISE LPKSIGKLEK
LEELLAKHCE GLQGEIPSEI GTLSSLTILD LSFTRISSLP PTLSKLSNLQ TLNLEFCHEL
RELSGLPKSL VTLHVMSKKL EELPDFSEMS GLTDLQLFCA VDKFQSNIGK LSRLEKLELY
IPRIKTLEFG VTSQLGSLSL SCREIETLPQ LPSTLSRLSL AHLNGTMKFP SIGNLKRLTF
LEFYSCSMGS DEFGNLGVVE LKSLDHLSAS KCNFSSIGGP PLPERLKVLC MRECEFLDGL
LDLSSLKSLM CLEIMDCQLL TEIRGLGKLE SVEEIIICYC NSLETLGDLS DLEKLEALHV
DSCKKLVEVK GLGRDGKGSQ LLSGYLRAST LGYVHESEIL KKRSYSEISS TLIPDKWRGW
RRLQSRPRSP KARSLAIPLQ ERDDCGGNGP DPGHHRPSEV ADDLPLVGGG QY
//
