ID   A0A218YXA5_9HELO        Unreviewed;      1619 AA.
AC   A0A218YXA5;
DT   27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT   27-SEP-2017, sequence version 1.
DT   08-NOV-2023, entry version 20.
DE   RecName: Full=Rap-GAP domain-containing protein {ECO:0000259|PROSITE:PS50085};
GN   ORFNames=B2J93_762 {ECO:0000313|EMBL:OWP00451.1};
OS   Marssonina coronariae.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Dermateaceae; Marssonina.
OX   NCBI_TaxID=503106 {ECO:0000313|EMBL:OWP00451.1, ECO:0000313|Proteomes:UP000242519};
RN   [1] {ECO:0000313|EMBL:OWP00451.1, ECO:0000313|Proteomes:UP000242519}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NL1 {ECO:0000313|EMBL:OWP00451.1,
RC   ECO:0000313|Proteomes:UP000242519};
RA   Cheng Q.;
RT   "Draft genome sequence of Marssonina coronaria NL1: causal agent of apple
RT   blotch.";
RL   Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OWP00451.1}.
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DR   EMBL; MZNU01000322; OWP00451.1; -; Genomic_DNA.
DR   STRING; 503106.A0A218YXA5; -.
DR   InParanoid; A0A218YXA5; -.
DR   OrthoDB; 20915at2759; -.
DR   Proteomes; UP000242519; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:InterPro.
DR   GO; GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
DR   GO; GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.11210; Rap/Ran-GAP; 1.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR035974; Rap/Ran-GAP_sf.
DR   InterPro; IPR000331; Rap/Ran_GAP_dom.
DR   InterPro; IPR018515; Tuberin-type_domain.
DR   InterPro; IPR027107; Tuberin/Ral-act_asu.
DR   InterPro; IPR024584; Tuberin_N.
DR   PANTHER; PTHR10063; TUBERIN; 1.
DR   PANTHER; PTHR10063:SF0; TUBERIN; 1.
DR   Pfam; PF11864; DUF3384; 1.
DR   Pfam; PF02145; Rap_GAP; 1.
DR   Pfam; PF03542; Tuberin; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF111347; Rap/Ran-GAP; 1.
DR   PROSITE; PS50085; RAPGAP; 1.
PE   4: Predicted;
KW   GTPase activation {ECO:0000256|ARBA:ARBA00022468};
KW   Reference proteome {ECO:0000313|Proteomes:UP000242519}.
FT   DOMAIN          1304..1547
FT                   /note="Rap-GAP"
FT                   /evidence="ECO:0000259|PROSITE:PS50085"
FT   REGION          1..62
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          640..663
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          842..868
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1078..1114
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1579..1605
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        11..62
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        852..868
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1079..1114
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1579..1597
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1619 AA;  179851 MW;  0F95EEB29B0E58B4 CRC64;
     MSPAGGDVAQ TPEPKSSSGF ASVFKSLTGG SRSTKNPNIS SPASFNGTSS LQPTIYPQST
     TYGGPPNYEH LYDKLKPGNA LADRIVAAEA LRRAVQDYPL SGVTSIFKQG NDLIESKNPR
     VARIAGFELL TACVKQTTST DPERLAYFHI LTAPANSEDF HLQLAALVEL AKNGKDLAGF
     HYEILPLLTV WLRHNFAITS AARRDTGRNR SSKSKAPLRE ETNLSLLFAF IVDVIKFGFS
     VSSEETTGDL IDVILHICVN TPLTGDLKAC INVINAIVTY GDIPGPKLLG CVKVLCSIHC
     LVNDAQPEAW RAISNLCRSH NGQKTIRILL NILQEPPVDS SSGKQTVREI RGALSVLERL
     FGKDGKNGYP LVPFTLLITA LEKVVAVEHV KVENDALHLI LSLLSDENQD VGKNCMDEDW
     SLMFDVVAKC ARRVLVNPEG RQLTIRSRVN SPLVKEEMGE QSMITSLAQT LYNIILRIEE
     LWTKFSDENF FQKEQCVRFF VTVHPHLPES CAKLVIDHYM EYRYCYPSDL DWKDNTKLVL
     SAFFTDRTQP THIRLHALKA ITDVFEVIEM MDEHEDPDTV QVFVMSILND IGDEKDTTIL
     QQVVAFAVAV AEKADETLFR YVIGAIRSSV ISDRLQSPLG SPTGSRHGLM NPSRSSTSSI
     PSTAIQTPSD VVTKGFILIF MRTMYDSTWK ALRVFDELLW IAKSHECETD ARISALKMMS
     RLRADWANGV FLTPFTESDG LAATLYRTAA SLARKQAIDD ATLLPRSARI EDSARISRSI
     SVNQTHPQVR QPFRTASGPT RTIQRNHQMW MSPDQDALPE PASGKASLIL KSVSAGSAAT
     YGVNPNGEKL GDHDSPVLRN GDEETTGSLH HKDHTVLDVS LYLETIIGLL RHGCDWEVYS
     YILAHLASQL TNQALFVGAI PQIRTLRELL CDQIKGGTYY EPPTSSGLRK ADVAICLFQI
     LNMVMSYHRH FSKVDQDDIV RTFLQGVGER TSKCCIHALS LCCHELPGST SKSLIHILSK
     MSQIITQSHV AVHILEFLVC LARLPDLYVN FREEEYRIVF AICFRYLQYV RDQQAKEIGK
     RNSNPSGRNS LVAFDTPRGN GTDSSPAESN FQPNTSDELP QYVYALAYHV IIFWFLALKL
     PDRAGQVSWI TRNLVSTDNN GKENIDEQAQ VTLDFMQRVA YADVDESGPD PSFTREVFGE
     IQKKRWIIGN SLVTVEQATR GDWAQITKRQ PSGTSCYIIQ EKFIRPPPHQ DPGLADVMKD
     GRVSDENVKL PSHLLLQLSA SIPLASEATR PIPLPNNDDM ERAVKSFNRL FTVDGHKVGV
     IYIGENQTNE VEILANIQGS SDYTDFLSRL GTLTKLKGAK FNTQGLDKEH DSDGKYTFCW
     RDRVTEIVFH VTTQMPTNLD NDPQCIGKKR HIGNDFVNII FNNSGLPFKF DTFPSQFNYV
     NIVITPESRA SFVATRLRSK MHADDAFYKV QVMSKPGFPE ISPAAEPKIM SLAALPSFIR
     LLALNASVFS LVWDNREGGE NVSSWRSRLQ AINRIRERYR VKGLVATATS PPGTSNGASV
     RDSINSLRRS SVANFLTSAT NGPEAASQRS SILSTADTEA GPLAGEEGLV ESLDFSRWA
//