ID A0A218Z178_9HELO Unreviewed; 997 AA.
AC A0A218Z178;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE SubName: Full=DUF221 domain protein {ECO:0000313|EMBL:OWP01821.1};
GN ORFNames=B2J93_515 {ECO:0000313|EMBL:OWP01821.1};
OS Marssonina coronariae.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Dermateaceae; Marssonina.
OX NCBI_TaxID=503106 {ECO:0000313|EMBL:OWP01821.1, ECO:0000313|Proteomes:UP000242519};
RN [1] {ECO:0000313|EMBL:OWP01821.1, ECO:0000313|Proteomes:UP000242519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NL1 {ECO:0000313|EMBL:OWP01821.1,
RC ECO:0000313|Proteomes:UP000242519};
RA Cheng Q.;
RT "Draft genome sequence of Marssonina coronaria NL1: causal agent of apple
RT blotch.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CSC1 (TC 1.A.17) family.
CC {ECO:0000256|ARBA:ARBA00007779}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWP01821.1}.
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DR EMBL; MZNU01000258; OWP01821.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A218Z178; -.
DR InParanoid; A0A218Z178; -.
DR OrthoDB; 1330110at2759; -.
DR Proteomes; UP000242519; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005227; F:calcium-activated cation channel activity; IEA:InterPro.
DR InterPro; IPR045122; Csc1-like.
DR InterPro; IPR003864; CSC1/OSCA1-like_7TM.
DR InterPro; IPR027815; CSC1/OSCA1-like_cyt.
DR InterPro; IPR032880; Csc1/OSCA1-like_N.
DR PANTHER; PTHR13018:SF154; DOMAIN PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G11660)-RELATED; 1.
DR PANTHER; PTHR13018; PROBABLE MEMBRANE PROTEIN DUF221-RELATED; 1.
DR Pfam; PF14703; PHM7_cyt; 1.
DR Pfam; PF02714; RSN1_7TM; 1.
DR Pfam; PF13967; RSN1_TM; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000242519};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 39..60
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 124..141
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 398..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 441..465
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 486..510
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 530..552
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 603..630
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 661..679
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 39..188
FT /note="CSC1/OSCA1-like N-terminal transmembrane"
FT /evidence="ECO:0000259|Pfam:PF13967"
FT DOMAIN 212..381
FT /note="CSC1/OSCA1-like cytosolic"
FT /evidence="ECO:0000259|Pfam:PF14703"
FT DOMAIN 392..674
FT /note="CSC1/OSCA1-like 7TM region"
FT /evidence="ECO:0000259|Pfam:PF02714"
FT REGION 280..303
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 864..885
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 932..981
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 280..294
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 997 AA; 111540 MW; B21A5559C2E15A28 CRC64;
MNAFTFIDSL IRRDEESGAK KLLDLLKNPF SAQLAQSSVL ASLGTSIGFT LLLAIGFSAL
RPFNSLVYAP KLKIADERHA PPPLGKGIFS WVAPILKTKE QDLIILIGLD AVVFLRILLM
CRNIFLVMTV IGCAILIPIN WTNSGGEAFK QATTLARVTP VNTFGSANWG MAICAWVFNS
IIAGFLWWNY RVILRLRRQY YDSPEYRASL HARTLMVNDI PKDFRSNEGI GRLIDQVAPT
SSFSRTAIAR NTKELPELIE QHNQTVRSLE KHLAKYLKDP NQLPSRRPEC KPSKDDPNWG
TYPKGQKLDA IEYLTGRIKQ LELEIKEVRL TVDNRNPLPY GFASYEEIAE AHSIAYAAKK
KHPEGTTIVL APRPNDIIWK NMPLNKSQRR RRRIVNNIWV TLLTLAWIAP NAMISIFVIS
LANLGHVWPA FQTSLERHTT WWSIVQGVAS PAITSLVYLV LPIIFRRLAI RAGDRTKTAR
ERHVAGELYT FFVFNFLIVF SSFSTVWTFV STIIENTNDG KDAWQAIQDA NFAQALFISL
CNISPFWITW LLQRNLGAAV DLAQLWTLVW SFCIRKFSNP TPREMIELTA PPAFDYASYY
NYFLFYSTVT LCFATIQPLA IPACALYFAL DVYLKKYLLL YIFITKTESG GMFWRMFFNR
MVFAAMISNL VVFLSVWVHG DGQHMEAFAI VPLPFLLGAF KWVCKRNFDD KIHYYVQASV
HKDPEADRSK LFDAKRDKLA ARFGHPALYR PLITPMVHAK AQNILASIYG GRLSDSNAVG
SSESASISGY SDTYALNPMQ VGHAGKKKTA GGIPGFEVVP ENKLDFAYFK GRHEFGDEHG
GGGGIYGRAE DIIRSDTPGS STIFGGSDSR PGTPNHPHLG GMGTPPPVPQ GERRMSGVSY
DAQGDGGRSG YHPVYGHYRN ESEVNLVVGA AEHPVSTPGP VGRSEVRDTS QERRAPGFLG
GGPQGYGGLP QEEDNDPNSY DYFRTRRQNA GWQGWGA
//
