ID A0A218ZHJ8_9HELO Unreviewed; 1263 AA.
AC A0A218ZHJ8;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Cell division control protein Cdc {ECO:0000313|EMBL:OWP07070.1};
GN ORFNames=B2J93_6650 {ECO:0000313|EMBL:OWP07070.1};
OS Marssonina coronariae.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC Helotiales; Dermateaceae; Marssonina.
OX NCBI_TaxID=503106 {ECO:0000313|EMBL:OWP07070.1, ECO:0000313|Proteomes:UP000242519};
RN [1] {ECO:0000313|EMBL:OWP07070.1, ECO:0000313|Proteomes:UP000242519}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NL1 {ECO:0000313|EMBL:OWP07070.1,
RC ECO:0000313|Proteomes:UP000242519};
RA Cheng Q.;
RT "Draft genome sequence of Marssonina coronaria NL1: causal agent of apple
RT blotch.";
RL Submitted (APR-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWP07070.1}.
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DR EMBL; MZNU01000020; OWP07070.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A218ZHJ8; -.
DR STRING; 503106.A0A218ZHJ8; -.
DR InParanoid; A0A218ZHJ8; -.
DR OrthoDB; 68574at2759; -.
DR Proteomes; UP000242519; Unassembled WGS sequence.
DR GO; GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
DR CDD; cd00155; RasGEF; 1.
DR CDD; cd06224; REM; 1.
DR CDD; cd11883; SH3_Sdc25; 1.
DR CDD; cd00201; WW; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR Gene3D; 1.10.840.10; Ras guanine-nucleotide exchange factors catalytic domain; 1.
DR Gene3D; 2.30.30.40; SH3 Domains; 1.
DR Gene3D; 1.20.870.10; Son of sevenless (SoS) protein Chain: S domain 1; 1.
DR InterPro; IPR008937; Ras-like_GEF.
DR InterPro; IPR000651; Ras-like_Gua-exchang_fac_N.
DR InterPro; IPR019804; Ras_G-nucl-exch_fac_CS.
DR InterPro; IPR023578; Ras_GEF_dom_sf.
DR InterPro; IPR001895; RASGEF_cat_dom.
DR InterPro; IPR036964; RASGEF_cat_dom_sf.
DR InterPro; IPR036028; SH3-like_dom_sf.
DR InterPro; IPR001452; SH3_domain.
DR InterPro; IPR001202; WW_dom.
DR PANTHER; PTHR23113; GUANINE NUCLEOTIDE EXCHANGE FACTOR; 1.
DR PANTHER; PTHR23113:SF99; RAP GUANINE NUCLEOTIDE EXCHANGE FACTOR 1; 1.
DR Pfam; PF00617; RasGEF; 1.
DR Pfam; PF00618; RasGEF_N; 1.
DR Pfam; PF00018; SH3_1; 1.
DR PRINTS; PR00452; SH3DOMAIN.
DR SMART; SM00147; RasGEF; 1.
DR SMART; SM00229; RasGEFN; 1.
DR SMART; SM00326; SH3; 1.
DR SUPFAM; SSF48366; Ras GEF; 1.
DR SUPFAM; SSF50044; SH3-domain; 1.
DR PROSITE; PS00720; RASGEF; 1.
DR PROSITE; PS50009; RASGEF_CAT; 1.
DR PROSITE; PS50212; RASGEF_NTER; 1.
DR PROSITE; PS50002; SH3; 1.
PE 4: Predicted;
KW Cell cycle {ECO:0000313|EMBL:OWP07070.1};
KW Cell division {ECO:0000313|EMBL:OWP07070.1};
KW Guanine-nucleotide releasing factor {ECO:0000256|ARBA:ARBA00022658,
KW ECO:0000256|PROSITE-ProRule:PRU00168};
KW Reference proteome {ECO:0000313|Proteomes:UP000242519};
KW SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW ProRule:PRU00192}.
FT DOMAIN 73..132
FT /note="SH3"
FT /evidence="ECO:0000259|PROSITE:PS50002"
FT DOMAIN 812..945
FT /note="N-terminal Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50212"
FT DOMAIN 981..1218
FT /note="Ras-GEF"
FT /evidence="ECO:0000259|PROSITE:PS50009"
FT REGION 137..180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 220..321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 698..767
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 148..166
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 220..239
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 276..290
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 299..314
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 711..740
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1263 AA; 142145 MW; 67812526AF2BBA56 CRC64;
MLMTLRGNGI FPDQQNTQSL NNFTPKSSAN LVPPSLCPPA QYPLSAHGRT AAPRAAKRKS
PPLMNGLLGN APQPVMYVRA LYDYEADDRT SLSFHEGDII QVITQLESGW WDGVINGVRG
WFPSNYCQVI ANPEEALDGK HDGTADDVEE GDVEDDEEEE DHRGESEDQY EAESAESERH
EVTYLPLEGS SENARAGADF WIPQATPDGR LFYFNTETGE SSMELPLESP SSGTENGPRD
RMSVNIPEKT RPPPEMMARG YVQDDDEESD GNSTSELDRE SLMLASQNSH PRKRRSLESQ
GVSPATSMDS MNGASPIVRS RPADPFVNPS LSMVTAMPIL GPSTTSFTNA SSLNPAQAAT
LTRSLFDEGS AVPLTWNRLV ANMKKAVDRY REAISRNERS EYVRRAEDIS DHLRLLLAAG
SGTTDNHSGQ PSIISTNKAL YPHFRDMMSK FSKLVISSHI AAADRPNAES YQKCLQEADG
VLQGVFSYVE VARQQRGEDI PRLLPGFVIG STAGGSWRNN GLVFRDLLHS RFLDEDESYS
APAATLNANL MERLDDLKRM LTSSIRQLEE HLLVTEKIIT PHRHEVIGNN VCTAAKKVLE
VFRPWISTVE SINLSSLVHS FQNPSLLDFA QHKQSLYDNV SDLILACQSV AGPLGDEWAE
VRGESLEARL SHVRSCAKQL ETNCSQIGFS LQLLGEQVQM ASPQDPEPPP PPPRDDNRRD
PASRRVESMP YDRSHQRTDS RLRPAMAGIG HSQSYSEGDP AGNYRMGENS KVRKFFGEEP
VRASEQQQQQ DETPDCLRLD HEEEISYDFK VSPPQLKGGT LLALVEQLTR HDKLEASFNN
TFLLTYRSFT TARELFELLV RRFQIQPPEG MVQSDYEMWR DRKQKPIRFR VVNILKSWFD
NFWMEDQSDE TKALIRDVYT FARDTVKTTE TPGSGPLMAV LEQRLRGQDT TAKRLVLTLN
QSTPHPIMPK NMKKLKFLDI DVTEFARQLT IVESKLYGKI KPTECLNKTW QKKVGENDPE
PAPNVKALIL HSNQLTNWVA EMILTQLDVK KRVVVIKHFV LVADKCRQLN NYSTLTSIIS
ALGTAPIHRL KRTWDQVPAK TTAILESMRR LMGSTKNFGE YRESLHLANP PCIPFFGVYL
TDLTFIEDGI PSIIKKSTLV NFAKRAKTAE VIRDIQQYQN APYPLQAVNE LQDYILSNMQ
AAGDVHEMYE RSLAVEPRER EDEKIVRYVG TQDAASLSLS YDGLKSRYEH PHNPHWPMRK
CAY
//
