ID A0A219AL58_9EURY Unreviewed; 343 AA.
AC A0A219AL58;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=DNA modification methylase {ECO:0000313|EMBL:OWT33338.1};
GN ORFNames=BGI41_02925 {ECO:0000313|EMBL:OWT33338.1};
OS Methanobrevibacter sp. 87.7.
OC Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC Methanobacteriales; Methanobacteriaceae; Methanobrevibacter.
OX NCBI_TaxID=387957 {ECO:0000313|EMBL:OWT33338.1, ECO:0000313|Proteomes:UP000197485};
RN [1] {ECO:0000313|EMBL:OWT33338.1, ECO:0000313|Proteomes:UP000197485}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=87.7 {ECO:0000313|EMBL:OWT33338.1,
RC ECO:0000313|Proteomes:UP000197485};
RA Yeoman C., Mosoni P., White B.;
RT "De novo assembly of methanobrevibacter sp 87.7.";
RL Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWT33338.1}.
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DR EMBL; MRCT01000036; OWT33338.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A219AL58; -.
DR OrthoDB; 7080at2157; -.
DR Proteomes; UP000197485; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0160102; F:tRNA (guanine(10)-N2)-methyltransferase activity; IEA:InterPro.
DR GO; GO:0030488; P:tRNA methylation; IEA:InterPro.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR InterPro; IPR005885; TrmG10.
DR NCBIfam; TIGR01177; TIGR01177 family methyltransferase; 1.
DR PANTHER; PTHR13370; RNA METHYLASE-RELATED; 1.
DR PANTHER; PTHR13370:SF3; TRNA (GUANINE(10)-N2)-METHYLTRANSFERASE HOMOLOG; 1.
DR Pfam; PF02926; THUMP; 1.
DR Pfam; PF01170; UPF0020; 1.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR SUPFAM; SSF143437; THUMP domain-like; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
DR PROSITE; PS51165; THUMP; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:OWT33338.1};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00529};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW tRNA-binding {ECO:0000256|ARBA:ARBA00022555}.
FT DOMAIN 55..153
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
SQ SEQUENCE 343 AA; 38972 MW; ED1D066063EC4843 CRC64;
MELLLIQSQE HETLPIAELK AVIEAENFNC NIEKLRPGLV ILSSIPEDDF DYTYKRLVER
LALTHQINNV LLTSNLDNLD NDIASIDWDN IINETFAVRT KTFDSNVDVE ACERHIGSII
LNNSNNIKVN LSNPGTKVRL IIYKNTVYIT KEDYVLNKKY FQDFKPHKRP FFHPGCMSPK
LARCMVNLSR IKKGELLLDP FCGTGGSLME GGLIGARVVG TDVDWNMKNG AAINCEYLGI
KDYKTFKVDI NELNMYELCD AVVTDPPYGI STTTGGRDDL IFKDFLVAIK RNMKKDALLV
MASPHFVDID KYLDEIGFKL LERYEIKVHR SLTRIISVIA QDV
//
