ID   A0A219ALH4_9EURY        Unreviewed;       361 AA.
AC   A0A219ALH4;
DT   27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT   27-SEP-2017, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=SAM-dependent methyltransferase {ECO:0000313|EMBL:OWT33458.1};
GN   ORFNames=BGI41_02380 {ECO:0000313|EMBL:OWT33458.1};
OS   Methanobrevibacter sp. 87.7.
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanobrevibacter.
OX   NCBI_TaxID=387957 {ECO:0000313|EMBL:OWT33458.1, ECO:0000313|Proteomes:UP000197485};
RN   [1] {ECO:0000313|EMBL:OWT33458.1, ECO:0000313|Proteomes:UP000197485}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=87.7 {ECO:0000313|EMBL:OWT33458.1,
RC   ECO:0000313|Proteomes:UP000197485};
RA   Yeoman C., Mosoni P., White B.;
RT   "De novo assembly of methanobrevibacter sp 87.7.";
RL   Submitted (DEC-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OWT33458.1}.
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DR   EMBL; MRCT01000027; OWT33458.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A219ALH4; -.
DR   OrthoDB; 8079at2157; -.
DR   Proteomes; UP000197485; Unassembled WGS sequence.
DR   GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR   GO; GO:0030488; P:tRNA methylation; IEA:UniProt.
DR   CDD; cd02440; AdoMet_MTases; 1.
DR   Gene3D; 3.30.70.2580; -; 1.
DR   Gene3D; 3.30.300.110; Met-10+ protein-like domains; 1.
DR   Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR   InterPro; IPR030382; MeTrfase_TRM5/TYW2.
DR   InterPro; IPR029063; SAM-dependent_MTases_sf.
DR   InterPro; IPR040601; Trm5_N.
DR   PANTHER; PTHR23245:SF36; TRNA (GUANINE(37)-N1)-METHYLTRANSFERASE; 1.
DR   PANTHER; PTHR23245; TRNA METHYLTRANSFERASE; 1.
DR   Pfam; PF02475; Met_10; 1.
DR   Pfam; PF18093; Trm5_N; 1.
DR   SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR   PROSITE; PS51684; SAM_MT_TRM5_TYW2; 1.
PE   4: Predicted;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW   ECO:0000313|EMBL:OWT33458.1};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:OWT33458.1}.
FT   DOMAIN          111..361
FT                   /note="SAM-dependent methyltransferase TRM5/TYW2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51684"
SQ   SEQUENCE   361 AA;  41884 MW;  C0B7F0BA846D533E CRC64;
     MQSLKISLPA VDEVRKILMD MEIMDMDHRI KPEKDYGYIG ITAPVNDEEI QMMIEKAGKV
     EKVQKLLNGR PLEIEVVDKE LELIPRYPHS VREMLKGKLS DQEITDLHNS YDIIGKIVIV
     EIPENLRKYK KLIGKTTLKF TKRDSVYMKN SPIKGVTRVR DIEFLCGVDN PITIHKEQKI
     RLKLDVSKVY FSPRLTNERK RIRDISHDGE KILDMFCGVG PFPIVIASKR DVDITAVDIN
     DVAIEYLKEN IKMNKLKGRI TPICGDIKEV IKDKLNNQKF DRIIMNLPGT AYDFLDYAFE
     LIANNGIIHY YEFAPNCEEG RKKLEDKAKE HNKKIKIEKC HKVRSTSPGM WQMAFDCRVN
     Y
//