ID A0A219AMS1_METCM Unreviewed; 374 AA.
AC A0A219AMS1;
DT 27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT 27-SEP-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=ribonuclease H {ECO:0000256|ARBA:ARBA00012180};
DE EC=3.1.26.4 {ECO:0000256|ARBA:ARBA00012180};
GN ORFNames=VFPPC_18653 {ECO:0000313|EMBL:OWT42227.1};
OS Pochonia chlamydosporia 170.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC Hypocreomycetidae; Hypocreales; Clavicipitaceae; Pochonia.
OX NCBI_TaxID=1380566 {ECO:0000313|EMBL:OWT42227.1, ECO:0000313|Proteomes:UP000078397};
RN [1] {ECO:0000313|EMBL:OWT42227.1, ECO:0000313|Proteomes:UP000078397}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=170 {ECO:0000313|EMBL:OWT42227.1};
RX PubMed=27416025;
RA Wang G., Liu Z., Lin R., Li E., Mao Z., Ling J., Yang Y., Yin W.B., Xie B.;
RT "Biosynthesis of antibiotic leucinostatins in bio-control fungus
RT Purpureocillium lilacinum and their inhibition on phytophthora revealed by
RT genome mining.";
RL PLoS Pathog. 12:E1005685-E1005685(2016).
CC -!- SIMILARITY: Belongs to the RNase H family.
CC {ECO:0000256|ARBA:ARBA00005300}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:OWT42227.1}.
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DR EMBL; LSBJ02000041; OWT42227.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A219AMS1; -.
DR STRING; 1380566.A0A219AMS1; -.
DR OrthoDB; 1438008at2759; -.
DR Proteomes; UP000078397; Unassembled WGS sequence.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR GO; GO:0090304; P:nucleic acid metabolic process; IEA:UniProt.
DR CDD; cd13934; RNase_H_Dikarya_like; 1.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR002156; RNaseH_domain.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10642; RIBONUCLEASE H1; 1.
DR PANTHER; PTHR10642:SF26; RIBONUCLEASE H1; 1.
DR Pfam; PF00075; RNase_H; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR PROSITE; PS50879; RNASE_H_1; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000078397}.
FT DOMAIN 198..358
FT /note="RNase H type-1"
FT /evidence="ECO:0000259|PROSITE:PS50879"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 39..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 54..69
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 374 AA; 41462 MW; D9234448076CC281 CRC64;
MSPGSFEYSS ASPVNSPRTT AQYNSTMLSH LHVIDDSDAD DGIGHVVDDS ESDDGSGYVV
DDSDSDDSIG PVELPDGRLV CRPHGLTFCP YCCVDFSFME ELLEDPEERL ERETNELYEQ
LSDEMQADID ARWVPPEGLQ TVQHTMETME PKLASTSSIQ PHHRNLAAAP SDEAQDVSFP
PSSIRPIPPV ARFIRRDDSE QLLIYADGAC LNNGQPNPKA GWAFVFKPDT NQPSGIVSAR
LEKKGPFGDA FAQTSNRAEL RAVLAALRFR HWRGEGFSTL VFATDSEYVA EGATSWIRGW
VRNGWKTSTG ADVKNKDMCE VLLGEVERWD DEGLKIQFWR IPRTLNGMAD SAAKQAARKV
EDPDDYRDVL GVLT
//
