ID   A0A219APV1_METCM        Unreviewed;      1392 AA.
AC   A0A219APV1;
DT   27-SEP-2017, integrated into UniProtKB/TrEMBL.
DT   27-SEP-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=NACHT domain-containing protein {ECO:0000313|EMBL:OWT42731.1};
GN   ORFNames=VFPPC_18144 {ECO:0000313|EMBL:OWT42731.1};
OS   Pochonia chlamydosporia 170.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Clavicipitaceae; Pochonia.
OX   NCBI_TaxID=1380566 {ECO:0000313|EMBL:OWT42731.1, ECO:0000313|Proteomes:UP000078397};
RN   [1] {ECO:0000313|EMBL:OWT42731.1, ECO:0000313|Proteomes:UP000078397}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=170 {ECO:0000313|EMBL:OWT42731.1};
RX   PubMed=27416025;
RA   Wang G., Liu Z., Lin R., Li E., Mao Z., Ling J., Yang Y., Yin W.B., Xie B.;
RT   "Biosynthesis of antibiotic leucinostatins in bio-control fungus
RT   Purpureocillium lilacinum and their inhibition on phytophthora revealed by
RT   genome mining.";
RL   PLoS Pathog. 12:E1005685-E1005685(2016).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:OWT42731.1}.
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DR   EMBL; LSBJ02000007; OWT42731.1; -; Genomic_DNA.
DR   RefSeq; XP_018139208.1; XM_018287890.1.
DR   STRING; 1380566.A0A219APV1; -.
DR   GeneID; 28851884; -.
DR   KEGG; pchm:VFPPC_18144; -.
DR   OrthoDB; 1765294at2759; -.
DR   Proteomes; UP000078397; Chromosome 7.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   GO; GO:0009116; P:nucleoside metabolic process; IEA:InterPro.
DR   Gene3D; 1.20.5.340; -; 5.
DR   Gene3D; 3.40.50.1580; Nucleoside phosphorylase domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR007111; NACHT_NTPase.
DR   InterPro; IPR035994; Nucleoside_phosphorylase_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR46082:SF11; AAA+ ATPASE DOMAIN-CONTAINING PROTEIN-RELATED; 1.
DR   PANTHER; PTHR46082; ATP/GTP-BINDING PROTEIN-RELATED; 1.
DR   Pfam; PF05729; NACHT; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF53167; Purine and uridine phosphorylases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000078397}.
FT   DOMAIN          400..577
FT                   /note="NACHT"
FT                   /evidence="ECO:0000259|Pfam:PF05729"
SQ   SEQUENCE   1392 AA;  155004 MW;  717E7ED6AE99B74B CRC64;
     MSDPKKYTVG WICAIRTELV AAQAFLDETH EQPKEQGPND SNHYVLGRMA HHNVVIACLP
     GGEYGTASAA GVAINLLRSF PTIRIGLMVG IGGGAPTKKH DIRLGDVVIS MPSNGRGGVF
     QYDFGKTIQG QAFVETGFLN QPPDLLRTAV EAVAAKYELD GHKLVESVNK SLDRKKRLRK
     KYSCPTSSDV LYKSDFTHCG DELEGCETCG SDPSVAVTRP ERGEDEDNPA IHHGLIASAN
     QLMKDALVRD KLATEKGVLC FEMEAAGLMN RFPCIVIRGI CDYSDTHKNK EWQGFAAMMA
     AAYAKDLLHQ MPASKVECEK SIHDMLSSID GGINSLCLTT EMVKSGVDSA NEQEIRNWFS
     TTPISTTYNK SIQDRTPGTG QWLLSSQSYK AWKGNVSGLL WLYGAAGSGK TMLCSTVVQD
     VSDHVQHDTG RKQAFWYFRF SDIATQNVSS MVRSFIRQLS PSPPLASTQK LWKEHSERGS
     EPTLNELTAI LGDIINDSKE VFVIIDALDE CQQTSQLQER TSLLRYINTC LNRHKDNLHI
     LVTSRVDHDI KSALEHYKAI KIEEWIDGDV RMYIEKQIHS GCLAEYQDSV KNKIKESLLS
     TKERRFRWVD LQIRRLSDCN TEDQIATALR TVPETLEDIY KEALEKVPLK DGKVAREILM
     WLCFSLRPMT AGEIAAAVGL LQPENALRIC STMLVTLIHE HTEGILQLAH FTVKEYLVVL
     RACNNTLEHQ FTEESAQDTL ARTTVSCLLE SKTLGQSTFA SPNRLLDYSA RFWYEHAIIL
     EGRDEYASLR KAIDQLFSHE YSAEYELWLK TYNPDNPYAN PYALTKEKNT PHPLYYASFL
     GFSHSVRKLL LEGGKVEEEG RPGNAFLAAV SNGHESVVKE FLERLPPPDE VEVCRVIKVL
     RRNAGNILSM YLERYTFEIT ELILMAAVES LQPEILSMLR RFGGGEVDVP EYMVQIAAVT
     AAESERKGME TLAMLLDRKG EEIKITEKVV MAAAGEKAGG SGVMAMLLDR RGEEIQITEE
     VVMAALQNRW SGQEILAVLL DRKGQEIETT KTLVTVAAMG SKRGKVILTM LLERRGEEIK
     ITEEVLIAAA KNERSGKEIL TMLLDRKGEE IKITGEVVMA AANNTESGSG IMTVLLDRKG
     DDVKITDDMV EEFVRKFDKF FMSALLGWKG GDIKITEKLL IAAAKNEQNG REVLAVLVDK
     KGEEIKITAE VIAAVSENLR NWQAIMVLLL CQKGENIQIT DDAVAEIARR FDKFIILLLL
     GRKGGLIEIT EELMISAAEN ELNGKEILAL LLDRKRKDIK ITEGIMLAAV RNQCSGNDIV
     TLLLERSEED IQITDELVTA AAENKRHAGH IKALLLGRLQ KLNERSILPK NDIAIHDEKD
     AAISGDSGDC SI
//