ID   A0A219UQU2_9CAUD        Unreviewed;       252 AA.
AC   A0A219UQU2;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   08-NOV-2023, entry version 17.
DE   SubName: Full=Putative metallo-beta-lactamase superfamily protein {ECO:0000313|EMBL:ANY29282.1};
OS   Bacillus phage PK16.
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Herelleviridae; Bastillevirinae; Caeruleovirus.
OX   NCBI_TaxID=1873894 {ECO:0000313|EMBL:ANY29282.1, ECO:0000313|Proteomes:UP000226297};
RN   [1] {ECO:0000313|EMBL:ANY29282.1, ECO:0000313|Proteomes:UP000226297}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Kim K.-H., Choi T.-J.;
RL   Submitted (JUL-2016) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Counteracts the host Pycsar antiviral defense system.
CC       Phosphodiesterase that enables metal-dependent hydrolysis of host
CC       cyclic nucleotide Pycsar defense signals such as cCMP and cUMP.
CC       {ECO:0000256|ARBA:ARBA00034293}.
CC   -!- SIMILARITY: Belongs to the anti-Pycsar protein Apyc1 family.
CC       {ECO:0000256|ARBA:ARBA00034308}.
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DR   EMBL; KX495186; ANY29282.1; -; Genomic_DNA.
DR   Proteomes; UP000226297; Genome.
DR   Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   PANTHER; PTHR42663:SF6; HYDROLASE C777.06C-RELATED; 1.
DR   PANTHER; PTHR42663; HYDROLASE C777.06C-RELATED-RELATED; 1.
DR   Pfam; PF12706; Lactamase_B_2; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
PE   3: Inferred from homology;
FT   DOMAIN          16..222
FT                   /note="Metallo-beta-lactamase"
FT                   /evidence="ECO:0000259|SMART:SM00849"
SQ   SEQUENCE   252 AA;  29106 MW;  370AFF9F3E8781C3 CRC64;
     MFKFIGCGSA FNTRLGNNSA YIKEDGILFM IDCGSANFDR IMRSDLLDGV EDIVVLMTHT
     HPDHVGSLGD LIFYSYFCMG QVKVPNLTVY APYDMKISKV LQGMGVEREC YRLIQFDNSN
     EYPPGFHKDG LHLKFQVVPN RHVPELLCYG YLITYKDKTI YYSGDSNNIS PFILRMLENG
     EIDYFYQDTC QADYEGNVHL SLRKLSELIR PLHDRDKVYC MHLDEGFSRE EATKLGFNVV
     QPSYKFMIKE IE
//