ID A0A220U078_9BACI Unreviewed; 661 AA.
AC A0A220U078;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Acetoacetate--CoA ligase {ECO:0000313|EMBL:ASK61489.1};
GN ORFNames=CFK37_04525 {ECO:0000313|EMBL:ASK61489.1};
OS Virgibacillus phasianinus.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Virgibacillus.
OX NCBI_TaxID=2017483 {ECO:0000313|EMBL:ASK61489.1, ECO:0000313|Proteomes:UP000198312};
RN [1] {ECO:0000313|EMBL:ASK61489.1, ECO:0000313|Proteomes:UP000198312}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LM2416 {ECO:0000313|EMBL:ASK61489.1,
RC ECO:0000313|Proteomes:UP000198312};
RA Tak E.J., Bae J.-W.;
RT "Virgibacillus sp. LM2416.";
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CP022315; ASK61489.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A220U078; -.
DR KEGG; vil:CFK37_04525; -.
DR OrthoDB; 9778383at2; -.
DR Proteomes; UP000198312; Chromosome.
DR GO; GO:0030729; F:acetoacetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0006629; P:lipid metabolic process; IEA:InterPro.
DR CDD; cd05943; AACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR005914; Acac_CoA_synth.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR01217; ac_ac_CoA_syn; 1.
DR PANTHER; PTHR42921; ACETOACETYL-COA SYNTHETASE; 1.
DR PANTHER; PTHR42921:SF1; ACETOACETYL-COA SYNTHETASE; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598, ECO:0000313|EMBL:ASK61489.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000198312}.
FT DOMAIN 41..96
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 101..476
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 544..618
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 661 AA; 74741 MW; BDAACDE81FE0B6A4 CRC64;
MARTEEGTLL WEPSEKRKQN SNIYDYMNWL KKHKDLHFDN YHSLWKWSVD ELELFWASLW
DYFQIQSKED YQTVLTSHEM PGANWFTGSK INYTEHIFQN RDRHKPAIIH TSELRDQTEI
SWDQLYQDTA ALQLTLKYLG VEKGDRIVAY VANIYESVVA FLATASLGAI WSSASPDFGT
QSVIDRFKQI EPKVMVTVDG YRYSGKDFDR TSVVENIQSE LPTLEATIAI PYLNENATFD
GLKNVTSWKH AVTSKRELTL NFERVPFNDP LWVLFSSGTT GKPKPIVQSQ GGILMEHLKA
LTFHADLDES DRFFWFTTTG WMMWNFLVGG LLTGSTIILY DGNPGYPDKK MLWKMAEQTK
MTVFGTSASY ITACMKDGLV PKEEFNLQHL KNISSTGSPL PPEGFQWCYD NVKDDLWIAS
SSGGTDVCTA FILGAPILPV YAGELQCRGL GAKIESFTDE GKPAINVVGE LVLTEPFPSM
PIYFWNDKDG SRLHDSYFDV FPGIWRHGDY LKVTDRDTCV IYGRSDATIN RGGIRIGTSE
IYRAVDQVSA VADSLIVDIP DGDGDSSVPL FVLMKENTEL TDDIKQAIKK QIRTQCSPRH
VPTAIYSVPD LPKTLNGKKL EIPVKKILKG KSVKKVVNQG SLSNPSSLDY FVEFAKKHQK
A
//
