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Database: UniProt
Entry: A0A220U1P3_9BACI
LinkDB: A0A220U1P3_9BACI
Original site: A0A220U1P3_9BACI 
ID   A0A220U1P3_9BACI        Unreviewed;       271 AA.
AC   A0A220U1P3;
DT   25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT   25-OCT-2017, sequence version 1.
DT   24-JAN-2024, entry version 25.
DE   RecName: Full=Pur operon repressor {ECO:0000256|ARBA:ARBA00018449};
GN   ORFNames=CFK37_05860 {ECO:0000313|EMBL:ASK61713.1};
OS   Virgibacillus phasianinus.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Virgibacillus.
OX   NCBI_TaxID=2017483 {ECO:0000313|EMBL:ASK61713.1, ECO:0000313|Proteomes:UP000198312};
RN   [1] {ECO:0000313|EMBL:ASK61713.1, ECO:0000313|Proteomes:UP000198312}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LM2416 {ECO:0000313|EMBL:ASK61713.1,
RC   ECO:0000313|Proteomes:UP000198312};
RA   Tak E.J., Bae J.-W.;
RT   "Virgibacillus sp. LM2416.";
RL   Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the purine/pyrimidine phosphoribosyltransferase
CC       family. {ECO:0000256|ARBA:ARBA00008391}.
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DR   EMBL; CP022315; ASK61713.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A220U1P3; -.
DR   KEGG; vil:CFK37_05860; -.
DR   OrthoDB; 4213751at2; -.
DR   Proteomes; UP000198312; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR   GO; GO:0045982; P:negative regulation of purine nucleobase metabolic process; IEA:InterPro.
DR   CDD; cd06223; PRTases_typeI; 1.
DR   Gene3D; 3.40.50.2020; -; 1.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR000836; PRibTrfase_dom.
DR   InterPro; IPR029057; PRTase-like.
DR   InterPro; IPR015265; PuR_N.
DR   InterPro; IPR010078; PurR_Bsub.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   NCBIfam; TIGR01743; purR_Bsub; 1.
DR   PANTHER; PTHR43864; HYPOXANTHINE/GUANINE PHOSPHORIBOSYLTRANSFERASE; 1.
DR   PANTHER; PTHR43864:SF2; PUR OPERON REPRESSOR; 1.
DR   Pfam; PF00156; Pribosyltran; 1.
DR   Pfam; PF09182; PuR_N; 1.
DR   SUPFAM; SSF53271; PRTase-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000198312};
KW   Repressor {ECO:0000256|ARBA:ARBA00022491}.
FT   DOMAIN          2..71
FT                   /note="Bacterial purine repressor N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF09182"
FT   DOMAIN          105..248
FT                   /note="Phosphoribosyltransferase"
FT                   /evidence="ECO:0000259|Pfam:PF00156"
SQ   SEQUENCE   271 AA;  29761 MW;  DC69741C7B2F3F9E CRC64;
     MRRSDRLVAL TNYFLENPRE HVSLPYFSTL YNAAKSSISE DLDIIDRVFS DEGIGRLETV
     AGAAGGVKFI PDYTAEKSKQ FITDLCDTLE DSERLLPGGY LYMSDLLGNP ALVKEIGRIF
     ASKFTESNIE AVVTVATKGI PLAYAVATFL NVPVVIVRRD PMVTEGSSVS INYVSGSSRK
     IQTMVLPKRS LREGANVCII DDFMKAGGTI NGIVSLLGEF NANVKGIAVL AEADDEEDER
     VVEDYLSLVK ITHVDLKQKK IDVRPGNFQN K
//
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