ID A0A220VDM0_9GAMM Unreviewed; 343 AA.
AC A0A220VDM0;
DT 25-OCT-2017, integrated into UniProtKB/TrEMBL.
DT 25-OCT-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=lipopolysaccharide heptosyltransferase II {ECO:0000256|ARBA:ARBA00044042};
DE EC=2.4.99.24 {ECO:0000256|ARBA:ARBA00044042};
GN Name=waaF {ECO:0000313|EMBL:ASK78053.1};
GN ORFNames=CF386_02825 {ECO:0000313|EMBL:ASK78053.1};
OS Paraphotobacterium marinum.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Paraphotobacterium.
OX NCBI_TaxID=1755811 {ECO:0000313|EMBL:ASK78053.1, ECO:0000313|Proteomes:UP000242175};
RN [1] {ECO:0000313|EMBL:ASK78053.1, ECO:0000313|Proteomes:UP000242175}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NSCS20N07D {ECO:0000313|EMBL:ASK78053.1,
RC ECO:0000313|Proteomes:UP000242175};
RX PubMed=27154455; DOI=10.1099/ijsem.0.001142;
RA Huang Z., Dong C., Shao Z.;
RT "Paraphotobacterium marinum gen. nov., sp. nov., a member of the family
RT Vibrionaceae, isolated from surface seawater.";
RL Int. J. Syst. Evol. Microbiol. 66:3050-3056(2016).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ADP-L-glycero-beta-D-manno-heptose + an L-alpha-D-Hep-(1->5)-
CC [alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid A = ADP + an L-alpha-D-Hep-
CC (1->3)-L-alpha-D-Hep-(1->5)-[alpha-Kdo-(2->4)]-alpha-Kdo-(2->6)-lipid
CC A + H(+); Xref=Rhea:RHEA:74071, ChEBI:CHEBI:15378, ChEBI:CHEBI:61506,
CC ChEBI:CHEBI:193068, ChEBI:CHEBI:193069, ChEBI:CHEBI:456216;
CC EC=2.4.99.24; Evidence={ECO:0000256|ARBA:ARBA00043830};
CC -!- SIMILARITY: Belongs to the glycosyltransferase 9 family.
CC {ECO:0000256|ARBA:ARBA00043995}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CP022355; ASK78053.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A220VDM0; -.
DR KEGG; pmai:CF386_02825; -.
DR OrthoDB; 9797795at2; -.
DR Proteomes; UP000242175; Chromosome large.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:InterPro.
DR GO; GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:InterPro.
DR CDD; cd03789; GT9_LPS_heptosyltransferase; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR002201; Glyco_trans_9.
DR InterPro; IPR011910; RfaF.
DR NCBIfam; TIGR02195; heptsyl_trn_II; 1.
DR PANTHER; PTHR30160:SF7; ADP-HEPTOSE--LPS HEPTOSYLTRANSFERASE 2; 1.
DR PANTHER; PTHR30160; TETRAACYLDISACCHARIDE 4'-KINASE-RELATED; 1.
DR Pfam; PF01075; Glyco_transf_9; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Reference proteome {ECO:0000313|Proteomes:UP000242175};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:ASK78053.1}.
SQ SEQUENCE 343 AA; 39049 MW; 57FEEDA6DF1E0991 CRC64;
MMKSILIIAP AWLGDLVMSH ALLKKLKREQ TVQLDLAVPN WLVPVAKRIP EIRNIISIPF
KHKELKVYKR YLFSKSLRTY HYDQVIVIPK TFKSALLAYW SHVPLRTGWV GEQRYFLLND
LRKNMKKVHL NVNRYLQLGE KKNSALLNDP IPEKYYPKLM VNKKNLNHLV KKFNIPLETD
VIAICPGASG GEAKKWPKKY FSELIKDLIK KDFKILILGA PSDQARCDEI YNSINESQKD
SVINLCGSTS LEDLIDILSL CKTAVSNDSG NLFVAAAVGI NVVAIYGPTT PDYTPPLTKK
AKILHTDISC RPCHEKVCPL KHHKCMEELF PKMVSQAVLN FNS
//
